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Ernest Gallo Clinic and Research Center, University of California, San Francisco

1 ARTICLES PUBLISHED IN JoVE

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Medicine

Mouse Model of Middle Cerebral Artery Occlusion
Terrance Chiang 1, Robert O. Messing 1, Wen-Hai Chou 1,2
1Department of Neurology, Ernest Gallo Clinic and Research Center, University of California, San Francisco, 2Department of Biological Sciences, Kent State University

We demonstrate in the video a method for producing a middle cerebral artery occlusion in adult mice using an intraluminal monofilament. We also show how to evaluate the extent of cerebral infarction by 2,3,5-triphenyltetrazolium chloride (TTC) staining.

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