Department of Neurology
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Protein kinase C epsilon regulates gamma-aminobutyrate type A receptor sensitivity to ethanol and benzodiazepines through phosphorylation of gamma2 subunits.
The Journal of biological chemistry Nov, 2007 | Pubmed ID: 17875639
Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKC epsilon knockout mouse hearts.
American journal of physiology. Heart and circulatory physiology Jun, 2002 | Pubmed ID: 12003800
Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cepsilon.
The Journal of clinical investigation Oct, 2002 | Pubmed ID: 12370278
Conditional rescue of protein kinase C epsilon regulates ethanol preference and hypnotic sensitivity in adult mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2002 | Pubmed ID: 12427847
Protein kinase C-epsilon-null mice have decreased hypoxic pulmonary vasoconstriction.
American journal of physiology. Heart and circulatory physiology Apr, 2003 | Pubmed ID: 12505875
Genetic approaches to studying protein kinase C: an introduction.
Methods in molecular biology (Clifton, N.J.) , 2003 | Pubmed ID: 12840528
Animal models in the study of protein kinase C isozymes.
Methods in molecular biology (Clifton, N.J.) , 2003 | Pubmed ID: 12840529
Preservation of base-line hemodynamic function and loss of inducible cardioprotection in adult mice lacking protein kinase C epsilon.
The Journal of biological chemistry Jan, 2004 | Pubmed ID: 14600145
The mouse RACK1 gene is regulated by nuclear factor-kappa B and contributes to cell survival.
Molecular pharmacology Dec, 2003 | Pubmed ID: 14645685
Protein kinase C isozymes and addiction.
Molecular neurobiology Apr, 2004 | Pubmed ID: 15126682
Neutrophil protein kinase Cdelta as a mediator of stroke-reperfusion injury.
The Journal of clinical investigation Jul, 2004 | Pubmed ID: 15232611
The type 1 equilibrative nucleoside transporter regulates ethanol intoxication and preference.
Nature neuroscience Aug, 2004 | Pubmed ID: 15258586
Deletion of N-type calcium channels alters ethanol reward and reduces ethanol consumption in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2004 | Pubmed ID: 15525770
The mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine decreases ethanol consumption via a protein kinase C epsilon-dependent mechanism.
Molecular pharmacology Feb, 2005 | Pubmed ID: 15548766
Specific modulation of Na+ channels in hippocampal neurons by protein kinase C epsilon.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2005 | Pubmed ID: 15647496
Chronic ethanol exposure induces an N-type calcium channel splice variant with altered channel kinetics.
FEBS letters Jan, 2005 | Pubmed ID: 15670827
Protein kinase C isozymes in stroke.
Trends in cardiovascular medicine Feb, 2005 | Pubmed ID: 15885569
Role of the protein kinase C-epsilon-Raf-1-MEK-1/2-p44/42 MAPK signaling cascade in the activation of signal transducers and activators of transcription 1 and 3 and induction of cyclooxygenase-2 after ischemic preconditioning.
Circulation Sep, 2005 | Pubmed ID: 16172266
Acute functional tolerance to ethanol mediated by protein kinase Cepsilon.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Jan, 2007 | Pubmed ID: 16541084
PKCepsilon increases endothelin converting enzyme activity and reduces amyloid plaque pathology in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America May, 2006 | Pubmed ID: 16698938
Ethanol withdrawal induces hyperalgesia mediated by PKCepsilon.
The European journal of neuroscience Jul, 2006 | Pubmed ID: 16800864
Early editorial manuscript screening versus obligate peer review: a randomized trial.
Annals of neurology Apr, 2007 | Pubmed ID: 17444512
A semisynthetic epitope for kinase substrates.
Nature methods Jun, 2007 | Pubmed ID: 17486086
nPKCepsilon, a P2Y2-R downstream effector in regulated mucin secretion from airway goblet cells.
American journal of physiology. Cell physiology Nov, 2007 | Pubmed ID: 17728398
Alcohol-induced stress in painful alcoholic neuropathy.
The European journal of neuroscience Jan, 2008 | Pubmed ID: 18093169
Hypertensive encephalopathy and the blood-brain barrier: is deltaPKC a gatekeeper?
The Journal of clinical investigation Jan, 2008 | Pubmed ID: 18097480
The identification and characterization of novel PKCepsilon phosphorylation sites provide evidence for functional cross-talk within the PKC superfamily.
The Biochemical journal Apr, 2008 | Pubmed ID: 18237277
Neurotoxic catecholamine metabolite in nociceptors contributes to painful peripheral neuropathy.
The European journal of neuroscience Sep, 2008 | Pubmed ID: 18783367
A blocker of N- and T-type voltage-gated calcium channels attenuates ethanol-induced intoxication, place preference, self-administration, and reinstatement.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2008 | Pubmed ID: 18987207
Protein kinases and addiction.
Annals of the New York Academy of Sciences Oct, 2008 | Pubmed ID: 18991950
Protein kinase Cdelta regulates ethanol intoxication and enhancement of GABA-stimulated tonic current.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2008 | Pubmed ID: 19005054
PKCepsilon regulates behavioral sensitivity, binding and tolerance to the CB1 receptor agonist WIN55,212-2.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Jun, 2009 | Pubmed ID: 19158669
The role of the equilibrative nucleoside transporter 1 (ENT1) in transport and metabolism of ribavirin by human and wild-type or Ent1-/- mouse erythrocytes.
The Journal of pharmacology and experimental therapeutics Apr, 2009 | Pubmed ID: 19164463
The N-type calcium channel is a novel target for treating alcohol use disorders.
Channels (Austin, Tex.) Mar-Apr, 2009 | Pubmed ID: 19372737
Neurobiological mechanisms contributing to alcohol-stress-anxiety interactions.
Alcohol (Fayetteville, N.Y.) Nov, 2009 | Pubmed ID: 19913194
Status report: the Annals in 2010.
Annals of neurology Jan, 2010 | Pubmed ID: 20186980
The substrates and binding partners of protein kinase Cepsilon.
The Biochemical journal Apr, 2010 | Pubmed ID: 20350291
PKC-delta promotes renal tubular cell apoptosis associated with proteinuria.
Journal of the American Society of Nephrology : JASN Jul, 2010 | Pubmed ID: 20395372
GABAA receptor trafficking is regulated by protein kinase C(epsilon) and the N-ethylmaleimide-sensitive factor.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2010 | Pubmed ID: 20962217
Should the reorganization of addiction-related research across all the National Institutes of Health be structural?--The devil is truly in the details.
Alcoholism, clinical and experimental research Apr, 2011 | Pubmed ID: 21443646
How Should Addiction-Related Research at the National Institutes of Health be Reorganized?
Frontiers in psychiatry / Frontiers Research Foundation , 2011 | Pubmed ID: 21629835
Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer.
The Journal of clinical investigation Jul, 2011 | Pubmed ID: 21633170
Signaling Pathways Mediating Alcohol Effects.
Current topics in behavioral neurosciences Aug, 2011 | Pubmed ID: 21877259
Protein kinase C epsilon modulates nicotine consumption and dopamine reward signals in the nucleus accumbens.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2011 | Pubmed ID: 21911393
Fighting decision fatigue.
Annals of neurology Jan, 2012 | Pubmed ID: 22275264
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