Department of Immunology
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Ras mediates effector pathways responsible for pre-B cell survival, which is essential for the developmental progression to the late pre-B cell stage.
The Journal of experimental medicine Jul, 2000 | Pubmed ID: 10899904
Isotype-specific selection of high affinity memory B cells in nasal-associated lymphoid tissue.
The Journal of experimental medicine Dec, 2001 | Pubmed ID: 11733574
Studies on the generation and maintenance of mucosal cytotoxic T lymphocytes against human immunodeficiency virus type 1 Gag in mice.
AIDS research and human retroviruses Jun, 2003 | Pubmed ID: 12882656
Germinal center-associated nuclear protein contributes to affinity maturation of B cell antigen receptor in T cell-dependent responses.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2004 | Pubmed ID: 14715907
A subcutaneously injected UV-inactivated SARS coronavirus vaccine elicits systemic humoral immunity in mice.
International immunology Oct, 2004 | Pubmed ID: 15314040
Two waves of memory B-cell generation in the primary immune response.
International immunology May, 2005 | Pubmed ID: 15824068
Immunological detection of severe acute respiratory syndrome coronavirus by monoclonal antibodies.
Japanese journal of infectious diseases Apr, 2005 | Pubmed ID: 15858286
Novel role of the Ras cascade in memory B cell response.
Immunity Aug, 2005 | Pubmed ID: 16111632
Formalin-treated UV-inactivated SARS coronavirus vaccine retains its immunogenicity and promotes Th2-type immune responses.
Japanese journal of infectious diseases May, 2007 | Pubmed ID: 17515642
Memory B cells in systemic and mucosal immune response: implications for successful vaccination.
Bioscience, biotechnology, and biochemistry Oct, 2007 | Pubmed ID: 17928717
Protective immunity afforded by inactivated H5N1 (NIBRG-14) vaccine requires antibodies against both hemagglutinin and neuraminidase in mice.
The Journal of infectious diseases Jun, 2009 | Pubmed ID: 19385735
CD22 expression mediates the regulatory functions of peritoneal B-1a cells during the remission phase of contact hypersensitivity reactions.
Journal of immunology (Baltimore, Md. : 1950) May, 2010 | Pubmed ID: 20335532
Inactivated and adjuvanted whole-virion clade 2.3.4 H5N1 pre-pandemic influenza vaccine possesses broad protective efficacy against infection by heterologous clades of highly pathogenic H5N1 avian influenza virus in mice.
Vaccine Oct, 2011 | Pubmed ID: 21911027
Newly established monoclonal antibodies for immunological detection of H5N1 influenza virus.
Japanese journal of infectious diseases , 2012 | Pubmed ID: 22274153
Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2012 | Pubmed ID: 22308386
Primary and secondary B-cell responses to pulmonary virus infection.
Infectious disorders drug targets Jun, 2012 | Pubmed ID: 22394179
Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.
The Journal of experimental medicine Oct, 2012 | Pubmed ID: 23027924
Influenza A whole virion vaccine induces a rapid reduction of peripheral blood leukocytes via interferon-α-dependent apoptosis.
Vaccine Apr, 2013 | Pubmed ID: 23434386
Both mutated and unmutated memory B cells accumulate mutations in the course of the secondary response and develop a new antibody repertoire optimally adapted to the secondary stimulus.
International immunology Dec, 2013 | Pubmed ID: 24021876
Oral administration of Lactobacillus plantarum strain AYA enhances IgA secretion and provides survival protection against influenza virus infection in mice.
PloS one , 2014 | Pubmed ID: 24466081
Epitope mapping of the hemagglutinin molecule of A/(H1N1)pdm09 influenza virus by using monoclonal antibody escape mutants.
Journal of virology Nov, 2014 | Pubmed ID: 25122788
Distinct germinal center selection at local sites shapes memory B cell response to viral escape.
The Journal of experimental medicine Sep, 2015 | Pubmed ID: 26324444
EAF2 mediates germinal centre B-cell apoptosis to suppress excessive immune responses and prevent autoimmunity.
Nature communications Mar, 2016 | Pubmed ID: 26935903
Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis.
Nature communications Apr, 2016 | Pubmed ID: 27046227
Whole-Virion Influenza Vaccine Recalls an Early Burst of High-Affinity Memory B Cell Response through TLR Signaling.
Journal of immunology (Baltimore, Md. : 1950) 05, 2016 | Pubmed ID: 27053762
Regulated selection of germinal-center cells into the memory B cell compartment.
Nature immunology 07, 2016 | Pubmed ID: 27158841
Protective neutralizing influenza antibody response in the absence of T follicular helper cells.
Nature immunology Dec, 2016 | Pubmed ID: 27798619
Boosting of post-exposure human T-cell and B-cell recall responses in vivo by Burkholderia pseudomallei-related proteins.
Immunology 05, 2017 | Pubmed ID: 28066900
Role of germinal centers for the induction of broadly-reactive memory B cells.
Current opinion in immunology Apr, 2017 | Pubmed ID: 28355576
A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines.
Scientific reports 04, 2017 | Pubmed ID: 28455520
Adaptive B Cell Responses to Influenza Virus Infection in the Lung.
Viral immunology Jul/Aug, 2017 | Pubmed ID: 28661720
A unique nanoparticulate TLR9 agonist enables a HA split vaccine to confer FcγR-mediated protection against heterologous lethal influenza virus infection.
International immunology Feb, 2019 | Pubmed ID: 30535055
Efficient protection of mice from influenza A/H1N1pdm09 virus challenge infection via high avidity serum antibodies induced by booster immunizations with inactivated whole virus vaccine.
Heliyon Jan, 2019 | Pubmed ID: 30623129
Lin Sun1,
Naoko Kono2,
Hiroyuki Toh3,
Hanbing Xue1,
Kaori Sano4,5,
Tadaki Suzuki4,
Akira Ainai4,
Yasuko Orba6,
Junya Yamagishi7,8,
Hideki Hasegawa4,5,
Yoshimasa Takahashi9,
Shigeyuki Itamura2,
Kazuo Ohnishi9,10
1Graduate School of Life and Environmental Sciences, University of Tsukuba,
2Center for Influenza Virus Research, National Institute of Infectious Diseases,
3School of Science and Technology, Kwansei Gakuin University,
4Department of Pathology, National Institute of Infectious Diseases,
5Division of Infectious Diseases Pathology, Department of Global Infectious Diseases, Tohoku University Graduate School of Medicine,
6Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University,
7Division of Collaboration and Education, Research Center for Zoonosis Control, Hokkaido University,
8Global Station for Zoonosis Control, GI-CoRE, Hokkaido University,
9Department of Immunology, National Institute of Infectious Diseases,
10Faculty of Life and Environmental Sciences, University of Tsukuba
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