El Bachir Affar
Maisonneuve-Rosemont Hospital Research Center and Department of Medicine
University of Montréal
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A sensitive flow cytometry-based nucleotide excision repair assay unexpectedly reveals that mitogen-activated protein kinase signaling does not regulate the removal of UV-induced DNA damage in human cells.
The Journal of biological chemistry Feb, 2008 | Pubmed ID: 18093981
ATR kinase is required for global genomic nucleotide excision repair exclusively during S phase in human cells.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2008 | Pubmed ID: 19004803
Ikaros and GATA-1 combinatorial effect is required for silencing of human gamma-globin genes.
Molecular and cellular biology Mar, 2009 | Pubmed ID: 19114560
The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression.
Molecular and cellular biology Nov, 2010 | Pubmed ID: 20805357
Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90.
The Journal of experimental medicine Nov, 2010 | Pubmed ID: 21041454
PI 3 kinase related kinases-independent proteolysis of BRCA1 regulates Rad51 recruitment during genotoxic stress in human cells.
PloS one , 2010 | Pubmed ID: 21103343
Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2011 | Pubmed ID: 21285374
Roles of ubiquitin signaling in transcription regulation.
Cellular signalling Feb, 2012 | Pubmed ID: 22033037
Electron transfer dissociation (ETD): the mass spectrometric breakthrough essential for O-GlcNAc protein site assignments-a study of the O-GlcNAcylated protein host cell factor C1.
Proteomics Mar, 2013 | Pubmed ID: 23335398
Direct protein interactions are responsible for Ikaros-GATA and Ikaros-Cdk9 cooperativeness in hematopoietic cells.
Molecular and cellular biology Aug, 2013 | Pubmed ID: 23732910
Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O.
Molecular cell May, 2014 | Pubmed ID: 24703950
The IKAROS interaction with a complex including chromatin remodeling and transcription elongation activities is required for hematopoiesis.
PLoS genetics Dec, 2014 | Pubmed ID: 25474253
The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.
The Journal of biological chemistry Nov, 2015 | Pubmed ID: 26416890
The LMO2 oncogene regulates DNA replication in hematopoietic cells.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2016 | Pubmed ID: 26764384
BAP1 regulates IP3R3-mediated Ca flux to mitochondria suppressing cell transformation.
Nature 06, 2017 | Pubmed ID: 28614305
Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine.
Cell death and differentiation 11, 2018 | Pubmed ID: 30323273
Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1.
Nature communications 10, 2018 | Pubmed ID: 30349006
BAP1 regulates different mechanisms of cell death.
Cell death & disease Nov, 2018 | Pubmed ID: 30455474
Opto-magnetic capture of individual cells based on visual phenotypes.
eLife Apr, 2019 | Pubmed ID: 30969169
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