El Bachir Affar

A sensitive flow cytometry-based nucleotide excision repair assay unexpectedly reveals that mitogen-activated protein kinase signaling does not regulate the removal of UV-induced DNA damage in human cells.

ATR kinase is required for global genomic nucleotide excision repair exclusively during S phase in human cells.

Ikaros and GATA-1 combinatorial effect is required for silencing of human gamma-globin genes.

The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression.

Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90.

PI 3 kinase related kinases-independent proteolysis of BRCA1 regulates Rad51 recruitment during genotoxic stress in human cells.

Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway.

Roles of ubiquitin signaling in transcription regulation.

Electron transfer dissociation (ETD): the mass spectrometric breakthrough essential for O-GlcNAc protein site assignments-a study of the O-GlcNAcylated protein host cell factor C1.

Direct protein interactions are responsible for Ikaros-GATA and Ikaros-Cdk9 cooperativeness in hematopoietic cells.

Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O.

The IKAROS interaction with a complex including chromatin remodeling and transcription elongation activities is required for hematopoiesis.

The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.

The LMO2 oncogene regulates DNA replication in hematopoietic cells.

BAP1 regulates IP3R3-mediated Ca flux to mitochondria suppressing cell transformation.

Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine.

Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1.

BAP1 regulates different mechanisms of cell death.

Opto-magnetic capture of individual cells based on visual phenotypes.