Yibin Wang

Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure.

RelB modulation of IkappaBalpha stability as a mechanism of transcription suppression of interleukin-1alpha (IL-1alpha), IL-1beta, and tumor necrosis factor alpha in fibroblasts.

Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery.

Stress-activated MAP kinases in cardiac remodeling and heart failure; new insights from transgenic studies.

Return of calcium: manipulating intracellular calcium to prevent cardiac pathologies.

Nitric oxide donors protect murine myocardium against infarction via modulation of mitochondrial permeability transition.

Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load.

p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes.

Molecular and functional signature of heart hypertrophy during pregnancy.

Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptor.

JNK activation decreases PP2A regulatory subunit B56alpha expression and mRNA stability and increases AUF1 expression in cardiomyocytes.

Overexpression of bone morphogenetic protein 10 in myocardium disrupts cardiac postnatal hypertrophic growth.

Role of an alternatively spliced form of alphaII-spectrin in localization of connexin 43 in cardiomyocytes and regulation by stress-activated protein kinase.

A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development.

Gi alpha 1-mediated cardiac electrophysiological remodeling and arrhythmia in hypertrophic cardiomyopathy.

Mitogen-activated protein kinases in heart development and diseases.

Inducible and cardiac specific PTEN inactivation protects ischemia/reperfusion injury.

Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models.

Post-translational regulation of calsarcin-1 during pressure overload-induced cardiac hypertrophy.

Compensatory hypertrophy induced by ventricular cardiomyocyte-specific COX-2 expression in mice.

Specific regulation of noncanonical p38alpha activation by Hsp90-Cdc37 chaperone complex in cardiomyocyte.

MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart.

An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria.

Targeted disruption of Mapk14 (p38MAPKalpha) in granulosa cells and cumulus cells causes cell-specific changes in gene expression profiles that rescue COC expansion and maintain fertility.

Differential regulation of proteasome function in isoproterenol-induced cardiac hypertrophy.

Electrochemical properties and myocyte interaction of carbon nanotube microelectrodes.

Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale.

Absence of progeria-like disease phenotypes in knock-in mice expressing a non-farnesylated version of progerin.

Proteomic insights into cardiac cell death and survival.

Restriction of big hearts by a small RNA.

Analysis of transcriptome complexity through RNA sequencing in normal and failing murine hearts.

Cdc37/Hsp90 protein-mediated regulation of IRE1α protein activity in endoplasmic reticulum stress response and insulin synthesis in INS-1 cells.

Systems-based approaches to cardiovascular disease.

p38γ activity is required for maintenance of slow skeletal muscle size.

Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth.

Zebrafish as a model for cardiovascular development and disease.

Prostaglandin E2 in remote control of myocardial remodeling.

Global impact of RNA splicing on transcriptome remodeling in the heart.

Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits.

Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome.

Nuclear phosphatase PPM1G in cellular survival and neural development.

Mechanism-based engineering against anthracycline cardiotoxicity.

Systems proteomics of cardiac chromatin identifies nucleolin as a regulator of growth and cellular plasticity in cardiomyocytes.

Interferon regulatory factors in heart: stress response beyond inflammation.

Decoding the noncoding transcripts in human heart failure.

Blind dates in sciences: dealing with rejection in peer review.

IRE1 phosphatase PP2Ce regulates adaptive ER stress response in the postpartum mammary gland.

Mapping genetic contributions to cardiac pathology induced by Beta-adrenergic stimulation in mice.

Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.

Dawn of the Epi-LncRNAs: new path from Myheart.

Genetics of common forms of heart failure: challenges and potential solutions.

Hypertrophic preconditioning: short-term tricks for long-term gain.

The Genetic Basis of Coronary Artery Disease and Atrial Fibrillation: A Search for Disease Mechanisms and Therapeutic Targets.

A H(a)rd Way to Adapt in Cardiac Hypertrophy.

Deletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptation.

Activation of Notch3 promotes pulmonary arterial smooth muscle cells proliferation via Hes1/p27Kip1 signaling pathway.

p38 MAP kinases in the heart.

The elusive philosopher's stone in young blood.

M1 of Murine Gamma-Herpesvirus 68 Induces Endoplasmic Reticulum Chaperone Production.

DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States.

Positive Role for a Negative Calcineurin Regulator in Cardiac Hypertrophy.

Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure.

The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits.

Photochemical Generation of Benzyl Cations That Selectively Cross-Link Guanine and Cytosine in DNA.

Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model.

Decoding the Long Noncoding RNA During Cardiac Maturation: A Roadmap for Functional Discovery.

The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy.

Branched chain amino acid metabolic reprogramming in heart failure.

The chromatin-binding protein Smyd1 restricts adult mammalian heart growth.

Deconvolution of the Human Endothelial Transcriptome.

Operationalizing Precision Cardiovascular Medicine: Three Innovations.

Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice.

Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification.

A systems genetics approach identifies as a link between cardiomyocyte glucose utilization and hypertrophic response.

Inflammatory and apoptotic remodeling in autonomic nervous system following myocardial infarction.

A Path to Implement Precision Child Health Cardiovascular Medicine.

Cardiac myocyte p38α kinase regulates angiogenesis via myocyte-endothelial cell cross-talk during stress-induced remodeling in the heart.

High-Resolution Mapping of Chromatin Conformation in Cardiac Myocytes Reveals Structural Remodeling of the Epigenome in Heart Failure.

The Calcineurin-FoxO-MuRF1 signaling pathway regulates myofibril integrity in cardiomyocytes.

Untangle a Broken Heart via Janus Kinase 1.

Wnt11 regulates cardiac chamber development and disease during perinatal maturation.

A Sarcoplasmic Reticulum Localized Protein Phosphatase Regulates Phospholamban Phosphorylation and Promotes Ischemia Reperfusion Injury in the Heart.

A personalized, multiomics approach identifies genes involved in cardiac hypertrophy and heart failure.

The serine/threonine-protein kinase/endoribonuclease IRE1α protects the heart against pressure overload-induced heart failure.

Humanin analog enhances the protective effect of dexrazoxane against doxorubicin-induced cardiotoxicity.

Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis.

Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans.

EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs.

Epigenomic regulation of heart failure: integrating histone marks, long noncoding RNAs, and chromatin architecture.

Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure.

RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure.

Epigenetics in dilated cardiomyopathy.

Effects of branched-chain amino acids on glucose metabolism in obese, prediabetic men and women: a randomized, crossover study.

Glucagon Receptor Antagonism Ameliorates Progression of Heart Failure.

Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance.

Western Diet-Fed, Aortic-Banded Ossabaw Swine: A Preclinical Model of Cardio-Metabolic Heart Failure.

Isoproterenol-Induced Cardiac Diastolic Dysfunction in Mice: A Systems Genetics Analysis.