Department of Molecular Virology and Microbiology,
Departments of Molecular Virology and Microbiology and Medicine
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VLA-2 (alpha2beta1) integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment.
Journal of virology Feb, 2002 | Pubmed ID: 11773387
Early response to rotavirus infection involves massive B cell activation.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2002 | Pubmed ID: 12023371
Rotavirus antigenaemia and viraemia: a common event?
Lancet (London, England) Nov, 2003 | Pubmed ID: 14602437
Kinetics of rotavirus infection in mice are not altered in a ground-based model of spaceflight.
Aviation, space, and environmental medicine Mar, 2004 | Pubmed ID: 15018288
The VP7 outer capsid protein of rotavirus induces polyclonal B-cell activation.
Journal of virology Jul, 2004 | Pubmed ID: 15194774
Host, viral, and vaccine factors that determine protective efficacy induced by rotavirus and virus-like particles (VLPs).
Vaccine Feb, 2006 | Pubmed ID: 16191453
Active viremia in rotavirus-infected mice.
Journal of virology Jul, 2006 | Pubmed ID: 16775359
Rotavirus infection enhances lipopolysaccharide-induced intussusception in a mouse model.
Journal of virology Dec, 2006 | Pubmed ID: 17005639
Rotavirus: to the gut and beyond!
Current opinion in gastroenterology Jan, 2007 | Pubmed ID: 17133083
Expression of rotavirus NSP4 alters the actin network organization through the actin remodeling protein cofilin.
Journal of virology Apr, 2007 | Pubmed ID: 17229686
Rotavirus antigenemia in children is associated with viremia.
PLoS medicine Apr, 2007 | Pubmed ID: 17439294
Differential requirements for T cells in viruslike particle- and rotavirus-induced protective immunity.
Journal of virology Mar, 2008 | Pubmed ID: 18184712
Immune mediators of rotavirus antigenemia clearance in mice.
Journal of virology Aug, 2011 | Pubmed ID: 21593155
Probiotics stimulate enterocyte migration and microbial diversity in the neonatal mouse intestine.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology May, 2012 | Pubmed ID: 22267340
Host response to probiotics determined by nutritional status of rotavirus-infected neonatal mice.
Journal of pediatric gastroenterology and nutrition Sep, 2012 | Pubmed ID: 22343914
IgA is important for clearance and critical for protection from rotavirus infection.
Mucosal immunology Nov, 2012 | Pubmed ID: 22739233
Lymphotoxin alpha-deficient mice clear persistent rotavirus infection after local generation of mucosal IgA.
Journal of virology Jan, 2013 | Pubmed ID: 23097456
FoxP3+ regulatory T cells are not important for rotavirus clearance or the early antibody response to rotavirus.
Microbes and infection Jan, 2014 | Pubmed ID: 24095866
The gastrointestinal frontier: IgA and viruses.
Frontiers in immunology Nov, 2013 | Pubmed ID: 24348474
Human enteroids as an ex-vivo model of host-pathogen interactions in the gastrointestinal tract.
Experimental biology and medicine (Maywood, N.J.) Sep, 2014 | Pubmed ID: 24719375
Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology.
Journal of virology 01, 2016 | Pubmed ID: 26446608
Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology.
The Journal of biological chemistry Feb, 2016 | Pubmed ID: 26677228
Replication of human noroviruses in stem cell-derived human enteroids.
Science (New York, N.Y.) 09, 2016 | Pubmed ID: 27562956
A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection.
Proceedings of the National Academy of Sciences of the United States of America 01, 2017 | Pubmed ID: 28069942
Human Intestinal Enteroids: New Models to Study Gastrointestinal Virus Infections.
Methods in molecular biology (Clifton, N.J.) Mar, 2017 | Pubmed ID: 28361480
Gastrointestinal microphysiological systems.
Experimental biology and medicine (Maywood, N.J.) 10, 2017 | Pubmed ID: 28534432
Epithelial WNT Ligands Are Essential Drivers of Intestinal Stem Cell Activation.
Cell reports 01, 2018 | Pubmed ID: 29386123
Novel Segment- and Host-Specific Patterns of Enteroaggregative Adherence to Human Intestinal Enteroids.
mBio 02, 2018 | Pubmed ID: 29463660
Human organoid cultures: transformative new tools for human virus studies.
Current opinion in virology 04, 2018 | Pubmed ID: 29656244
Engineered Human Gastrointestinal Cultures to Study the Microbiome and Infectious Diseases.
Cellular and molecular gastroenterology and hepatology Mar, 2018 | Pubmed ID: 29675450
The Next MacGyver: A Platform to Study Intestinal Organoids Using High-Throughput Computer-Driven Microinjection.
Cellular and molecular gastroenterology and hepatology , 2018 | Pubmed ID: 30182047
Human Norovirus Cultivation in Nontransformed Stem Cell-Derived Human Intestinal Enteroid Cultures: Success and Challenges.
Viruses Jul, 2019 | Pubmed ID: 31336765
Use of organoids to study regenerative responses to intestinal damage.
American journal of physiology. Gastrointestinal and liver physiology 12, 2019 | Pubmed ID: 31589468
Gut Bacterial Bouncers: Keeping Viral Pathogens out of the Epithelium.
Cell host & microbe 11, 2019 | Pubmed ID: 31726023
Models of the Small Intestine: Engineering Challenges and Engineering Solutions.
Tissue engineering. Part B, Reviews 08, 2020 | Pubmed ID: 32046599
Human norovirus exhibits strain-specific sensitivity to host interferon pathways in human intestinal enteroids.
Proceedings of the National Academy of Sciences of the United States of America 09, 2020 | Pubmed ID: 32907944
Enteropathogenic Escherichia coli Infection in Cancer and Immunosuppressed Patients.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 05, 2021 | Pubmed ID: 32930708
Telomere dysfunction activates YAP1 to drive tissue inflammation.
Nature communications 09, 2020 | Pubmed ID: 32958778
Enteroaggregative E. coli Adherence to Human Heparan Sulfate Proteoglycans Drives Segment and Host Specific Responses to Infection.
PLoS pathogens 09, 2020 | Pubmed ID: 32986782
Epithelial WNT2B and Desert Hedgehog Are Necessary for Human Colonoid Regeneration after Bacterial Cytotoxin Injury.
iScience Oct, 2020 | Pubmed ID: 33089106
Intestinal stem cell-derived enteroids from morbidly obese patients preserve obesity-related phenotypes: Elevated glucose absorption and gluconeogenesis.
Molecular metabolism 02, 2021 | Pubmed ID: 33246140
Protein-Functionalized Poly(ethylene glycol) Hydrogels as Scaffolds for Monolayer Organoid Culture.
Tissue engineering. Part C, Methods 01, 2021 | Pubmed ID: 33334213
Organoids to Dissect Gastrointestinal Virus-Host Interactions: What Have We Learned?
Viruses 05, 2021 | Pubmed ID: 34071878
Telomere dysfunction instigates inflammation in inflammatory bowel disease.
Proceedings of the National Academy of Sciences of the United States of America 07, 2021 | Pubmed ID: 34253611
Use of human tissue stem cell-derived organoid cultures to model enterohepatic circulation.
American journal of physiology. Gastrointestinal and liver physiology 09, 2021 | Pubmed ID: 34288725
Drivers of transcriptional variance in human intestinal epithelial organoids.
Physiological genomics Nov, 2021 | Pubmed ID: 34612061
Organoid Models for Infectious Disease.
Annual review of medicine Jan, 2022 | Pubmed ID: 34644153
Single-cell sequencing of rotavirus-infected intestinal epithelium reveals cell-type specific epithelial repair and tuft cell infection.
Proceedings of the National Academy of Sciences of the United States of America 11, 2021 | Pubmed ID: 34732579
Looking on the horizon; potential and unique approaches to developing radiation countermeasures for deep space travel.
Life sciences in space research Nov, 2022 | Pubmed ID: 36336356
Infant and Adult Human Intestinal Enteroids are Morphologically and Functionally Distinct.
bioRxiv : the preprint server for biology Feb, 2024 | Pubmed ID: 37292968
Multiomic Investigations into Lung Health and Disease.
Microorganisms Aug, 2023 | Pubmed ID: 37630676
Human intestinal organoids from Cronkhite-Canada syndrome patients reveal link between serotonin and proliferation.
The Journal of clinical investigation Nov, 2023 | Pubmed ID: 37909332
Pediatric human nose organoids demonstrate greater susceptibility, epithelial responses, and cytotoxicity than adults during RSV infection.
bioRxiv : the preprint server for biology Feb, 2024 | Pubmed ID: 38352333
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