Frank Sobott

Combining density functional theory (DFT) and collision cross-section (CCS) calculations to analyze the gas-phase behaviour of small molecules and their protonation site isomers.

Opposite Structural Effects of Epigallocatechin-3-gallate and Dopamine Binding to α-Synuclein.

Conformational Space and Stability of ETD Charge Reduction Products of Ubiquitin.

Proton Dynamics in Protein Mass Spectrometry.

Analyzing complex mixtures of drug-like molecules: Ion mobility as an adjunct to existing liquid chromatography-(tandem) mass spectrometry methods.

Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics.

AtaT blocks translation initiation by N-acetylation of the initiator tRNA.

Specific sequences in the N-terminal domain of human small heat-shock protein HSPB6 dictate preferential hetero-oligomerization with the orthologue HSPB1.

Native Mass Spectrometry for the Characterization of Structure and Interactions of Membrane Proteins.

Apparent activation energies of protein-protein complex dissociation in the gas-phase determined by electrospray mass spectrometry.

Advances in native high-performance liquid chromatography and intact mass spectrometry for the characterization of biopharmaceutical products.

A homologue of the Parkinson's disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover.

Analysis of the natively unstructured RNA/protein-recognition core in the Escherichia coli RNA degradosome and its interactions with regulatory RNA/Hfq complexes.

Evaluation of ion mobility for the separation of glycoconjugate isomers due to different types of sialic acid linkage, at the intact glycoprotein, glycopeptide and glycan level.

The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere.

Fixed-Charge Trimethyl Pyrilium Modification for Enabling Enhanced Top-Down Mass Spectrometry Sequencing of Intact Protein Complexes.

Radical solutions: Principles and application of electron-based dissociation in mass spectrometry-based analysis of protein structure.

Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.

The effect of reactive oxygen and nitrogen species on the structure of cytoglobin: A potential tumor suppressor.

Editorial and Review: 30th ASMS Sanibel Conference on Mass Spectrometry-Computational Modelling in Mass Spectrometry and Ion Mobility: Methods for Ion Structure and Reactivity Determination.

masstodon: A Tool for Assigning Peaks and Modeling Electron Transfer Reactions in Top-Down Mass Spectrometry.

Recommendations for reporting ion mobility Mass Spectrometry measurements.

Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure.

A dual role in regulation and toxicity for the disordered N-terminus of the toxin GraT.

Cyclized NDGA modifies dynamic α-synuclein monomers preventing aggregation and toxicity.

Thermodynamic Stability of the Transcription Regulator PaaR2 from Escherichia coli O157:H7.

First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study.

Native Ion Mobility-Mass Spectrometry Reveals the Formation of β-Barrel Shaped Amyloid-β Hexamers in a Membrane-Mimicking Environment.

MIND: A Double-Linear Model To Accurately Determine Monoisotopic Precursor Mass in High-Resolution Top-Down Proteomics.

Structural mechanism of synergistic activation of Aurora kinase B/C by phosphorylated INCENP.

How metal cofactors drive dimer-dodecamer transition of the M42 aminopeptidase TmPep1050 of .

A cryo-EM grid preparation device for time-resolved structural studies.

Enhanced oligomerization of full-length RAGE by synergy of the interaction of its domains.

The Escherichia coli RnlA-RnlB toxin-antitoxin complex: production, characterization and crystallization.

Styrene maleic-acid lipid particles (SMALPs) into detergent or amphipols: An exchange protocol for membrane protein characterisation.

Allosteric modulation of the GTPase activity of a bacterial LRRK2 homolog by conformation-specific Nanobodies.

Sample deposition onto cryo-EM grids: from sprays to jets and back.

Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity.

Software Requirements for the Analysis and Interpretation of Native Ion Mobility Mass Spectrometry Data.

Computational Strategies and Challenges for Using Native Ion Mobility Mass Spectrometry in Biophysics and Structural Biology.

M42 aminopeptidase catalytic site: the structural and functional role of a strictly conserved aspartate residue.

Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry.

Need for Speed: Examining Protein Behavior during CryoEM Grid Preparation at Different Timescales.

Metal ions shape α-synuclein.

Toward Increased Reliability, Transparency, and Accessibility in Cross-linking Mass Spectrometry.

Effects of Detergent on α-Synuclein Structure. A Native MS-Ion Mobility Study.

Do Aptamers Always Bind? The Need for a Multifaceted Analytical Approach When Demonstrating Binding Affinity between Aptamer and Low Molecular Weight Compounds.

Further insights from structural mass spectrometry into endocytosis adaptor protein assemblies.

Aptamer-ligand recognition studied by native ion mobility-mass spectrometry.

Discriminative SKP2 Interactions with CDK-Cyclin Complexes Support a Cyclin A-Specific Role in p27KIP1 Degradation.

Cryo-EM structure of human mitochondrial HSPD1.

Unveiling the binding mode of perfluorooctanoic acid to human serum albumin.

Interrogating Membrane Protein Structure and Lipid Interactions by Native Mass Spectrometry.

Brazilin Removes Toxic Alpha-Synuclein and Seeding Competent Assemblies from Parkinson Brain by Altering Conformational Equilibrium.

A model of full-length RAGE in complex with S100B.

Structural modeling of a novel membrane-bound globin-coupled sensor in .

Structure of the endocytic adaptor complex reveals the basis for efficient membrane anchoring during clathrin-mediated endocytosis.

Entropic pressure controls the oligomerization of the Vibrio cholerae ParD2 antitoxin.

Profiling Dopamine-Induced Oxidized Proteoforms of β-synuclein by Top-Down Mass Spectrometry.

Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops.

On-grid and in-flow mixing for time-resolved cryo-EM.

Nanobody-aided crystallization of the transcription regulator PaaR2 from Escherichia coli O157:H7.