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Noninvasive and targeted delivery of therapeutics to the brain using focused ultrasound.
Neuropharmacology Jul, 2017 | Pubmed ID: 26907805
Time course of focused ultrasound effects on β-amyloid plaque pathology in the TgCRND8 mouse model of Alzheimer's disease.
Scientific reports 09, 2018 | Pubmed ID: 30232364
Evaluating the safety profile of focused ultrasound and microbubble-mediated treatments to increase blood-brain barrier permeability.
Expert opinion on drug delivery 02, 2019 | Pubmed ID: 30628455
Neutrophil recruitment and leukocyte response following focused ultrasound and microbubble mediated blood-brain barrier treatments.
Theranostics , 2021 | Pubmed ID: 33408773
Sunnybrook Research Institute
University of Toronto
Charissa Poon1,2,
Melina Mühlenpfordt*,3,
Marieke Olsman*,3,
Spiros Kotopoulis4,5,
Catharina de Lange Davies3,
Kullervo Hynynen1,2,6
1Physical Sciences Platform, Sunnybrook Research Institute,
2Institute of Biomedical Engineering, University of Toronto,
3Department of Physics, Norwegian University of Science and Technology,
4Department of Clinical Medicine, University of Bergen,
5, Exact Therapeutics AS,
6Department of Medical Biophysics, University of Toronto
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