School of Biomedical Engineering,
Department of Microbiology and Immunology,
Life Sciences Institute,
Department of Microbiology and Immunology, Life Sciences Institute
Dr. Carolina Tropini is an Assistant Professor at the University of British Columbia in the Department of Microbiology and Immunology and the School of Biomedical Engineering. She is a Paul Allen Distinguished Investigator and in 2020 she was the first Canadian to be awarded the Johnson & Johnson Women in STEM2D Scholar in the field of Engineering. She is a CIFAR Fellow in the Human & the Microbiome Program (2021-2026) and a Michael Smith Foundation for Health Research Scholar (2019-2024).
The Tropini lab is investigating how a disrupted physical environment due to altered nutrition or concurrent with intestinal diseases affects the microbiota and host at a multi-scale level. They are a cross-disciplinary group that incorporates techniques from microbiology, bioengineering and biophysics to create highly parallel assays and study how bacteria and microbial communities function, with the goal of translating the knowledge gained to improve human health.
Dr. Tropini conducted her Ph.D. in Biophysics at Stanford University. Her studies in the laboratory of Dr. KC Huang combined computational and experimental techniques to investigate bacterial mechanics and morphogenesis. In 2014 she received the James S. McDonnell Foundation Postdoctoral Fellowship Award and she joined the laboratory of Dr. Justin Sonnenburg at Stanford. During her post-doc, Dr. Tropini applied her background in biophysics to study the impact of physical perturbations on host-associated microbial communities living in the gut.
Multi-nanopore force spectroscopy for DNA analysis.
Biophysical journal Mar, 2007 | Pubmed ID: 17158571
Nonexponential kinetics of DNA escape from alpha-hemolysin nanopores.
Biophysical journal Dec, 2008 | Pubmed ID: 18775965
Megapixel digital PCR.
Nature methods Jul, 2011 | Pubmed ID: 21725299
The hygiene hypothesis, the COVID pandemic, and consequences for the human microbiome.
Proceedings of the National Academy of Sciences of the United States of America 02, 2021 | Pubmed ID: 33472859
Cause or effect? The spatial organization of pathogens and the gut microbiota in disease.
Microbes and infection Mar, 2021 | Pubmed ID: 33775859
How the Physical Environment Shapes the Microbiota.
mSystems Aug, 2021 | Pubmed ID: 34427510
A bacterial record collection.
Cell host & microbe Jul, 2022 | Pubmed ID: 35834961
Gut commensal Enterocloster species host inoviruses that are secreted in vitro and in vivo.
Microbiome Mar, 2023 | Pubmed ID: 36991500
Microbial endocrinology: the mechanisms by which the microbiota influences host sex steroids.
Trends in microbiology Nov, 2023 | Pubmed ID: 37100633
Single-strain behavior predicts responses to environmental pH and osmolality in the gut microbiota.
mBio Aug, 2023 | Pubmed ID: 37432034
The gut microbiota and its biogeography.
Nature reviews. Microbiology Feb, 2024 | Pubmed ID: 37740073
Time to rethink academic publishing: the peer reviewer crisis.
mBio Nov, 2023 | Pubmed ID: 37975666
Inoviruses.
Current biology : CB Dec, 2023 | Pubmed ID: 38113833
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