Rodrigo Pacheco

Role of dopamine in the physiology of T-cells and dendritic cells.

Emerging evidence for the role of neurotransmitters in the modulation of T cell responses to cognate ligands.

Stimulation of dopamine receptor D5 expressed on dendritic cells potentiates Th17-mediated immunity.

Dopamine receptor D3 expressed on CD4+ T cells favors neurodegeneration of dopaminergic neurons during Parkinson's disease.

Modulation of T-cell mediated immunity by dopamine receptor d5.

The dopaminergic system in autoimmune diseases.

Monoacylglycerol lipase inhibitor JZL184 is neuroprotective and alters glial cell phenotype in the chronic MPTP mouse model.

Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases.

Dopamine receptor D3 deficiency results in chronic depression and anxiety.

T-cell-mediated regulation of neuroinflammation involved in neurodegenerative diseases.

Regulation of the Neurodegenerative Process Associated to Parkinson's Disease by CD4+ T-cells.

Dopamine receptors D3 and D5 regulate CD4(+)T-cell activation and differentiation by modulating ERK activation and cAMP production.

Dopamine receptor D5 deficiency results in a selective reduction of hippocampal NMDA receptor subunit NR2B expression and impaired memory.

Increased expression with differential subcellular location of cytidine deaminase APOBEC3G in human CD4(+) T-cell activation and dendritic cell maturation.

Dopamine Receptor D3 Signaling on CD4+ T Cells Favors Th1- and Th17-Mediated Immunity.

Purinergic Signaling as a Regulator of Th17 Cell Plasticity.

The histone demethylase inhibitor GSK-J4 limits inflammation through the induction of a tolerogenic phenotype on DCs.

Pharmacologic antagonism of dopamine receptor D3 attenuates neurodegeneration and motor impairment in a mouse model of Parkinson's disease.

Inhibition of dopamine receptor D3 signaling in dendritic cells increases antigen cross-presentation to CD8 T-cells favoring anti-tumor immunity.

Targeting dopamine receptor D3 signalling in inflammation.

Galectin-8 as an immunosuppressor in experimental autoimmune encephalomyelitis and a target of human early prognostic antibodies in multiple sclerosis.

Caveolin-1 Expression Increases upon Maturation in Dendritic Cells and Promotes Their Migration to Lymph Nodes Thereby Favoring the Induction of CD8 T Cell Responses.

Myeloid CD11c Antigen-Presenting Cells Ablation Prevents Hypertension in Response to Angiotensin II Plus High-Salt Diet.

Dopaminergic Stimulation of Myeloid Antigen-Presenting Cells Attenuates Signal Transducer and Activator of Transcription 3-Activation Favouring the Development of Experimental Autoimmune Encephalomyelitis.

Smoking promotes exacerbated inflammatory features in dendritic cells of Chilean rheumatoid arthritis patients.

Dopamine Receptor D5 Signaling Plays a Dual Role in Experimental Autoimmune Encephalomyelitis Potentiating Th17-Mediated Immunity and Favoring Suppressive Activity of Regulatory T-Cells.

The ArcAB two-component regulatory system promotes resistance to reactive oxygen species and systemic infection by Salmonella Typhimurium.

Targeting the Dopaminergic System in Autoimmunity.

IRE1α Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8 T Cell Priming.

T-Cell-Driven Inflammation as a Mediator of the Gut-Brain Axis Involved in Parkinson's Disease.

Dendritic cells are crucial for cardiovascular remodeling and modulate neutrophil gelatinase-associated lipocalin expression upon mineralocorticoid receptor activation.

Dopamine Receptor D3 Expression Is Altered in CD4 T-Cells From Parkinson's Disease Patients and Its Pharmacologic Inhibition Attenuates the Motor Impairment in a Mouse Model.

STAT3 Activation in Combination with NF-KappaB Inhibition Induces Tolerogenic Dendritic Cells with High Therapeutic Potential to Attenuate Collagen-Induced Arthritis.

Cross-talk between T-cells and gut-microbiota in neurodegenerative disorders.

Editorial: Peripheral Immunity in Parkinson's Disease: Emerging Role and Novel Target for Therapeutics.

Dopamine receptor D3 signalling in astrocytes promotes neuroinflammation.

The Cross-Talk Between the Dopaminergic and the Immune System Involved in Schizophrenia.

Involvement of dopaminergic signaling in the cross talk between the renin-angiotensin system and inflammation.

Dopaminergic signalling limits suppressive activity and gut homing of regulatory T cells upon intestinal inflammation.

The demethylase inhibitor GSK-J4 limits inflammatory colitis by promoting de novo synthesis of retinoic acid in dendritic cells.

The Heteromeric Complex Formed by Dopamine Receptor D and CCR9 Leads the Gut Homing of CD4 T Cells Upon Inflammation.

Prenatal fluoxetine impairs non-hippocampal but not hippocampal memory in adult male rat offspring.

Allergens of the urushiol family promote mitochondrial dysfunction by inhibiting the electron transport at the level of cytochromes b and chemically modify cytochrome c.

Dopaminergic stimulation leads B-cell infiltration into the central nervous system upon autoimmunity.

Neuropilin-1 is present on Foxp3+ T regulatory cell-derived small extracellular vesicles and mediates immunity against skin transplantation.

Dopaminergic Inhibition of Human Neutrophils is Exerted Through D1-Like Receptors and Affected By Bacterial Infection.