Kyungpook National University

5 ARTICLES PUBLISHED IN JoVE

Bioengineering

Mansik Jeon^1,2, Jeehyun Kim³, Chulhong Kim^1,2

¹Department of Biomedical Engineering, University at Buffalo, The State University of New York, ²Department of Creative IT Engineering, Pohang University of Science and Technology (POSTECH) , ³School of Electrical Engineering and Computer Science, Kyungpook National University

Photoacoustic cystography (PAC) has a great potential to map urinary bladders, a radiation sensitive internal organ in pediatric patients, without using any ionizing radiation or toxic contrast agent. Here we demonstrate the use of PAC for mapping urinary bladders with an injection of optical-opaque tracers in rats in vivo.

Neuroscience

Acrylic Resin Molding Based Head Fixation Technique in Rodents

Mootaek Roh¹, Kyungmin Lee¹, Il-Sung Jang², Kyoungho Suk³, Maan-Gee Lee³

¹Department of Anatomy, School of Medicine and Brain Science and Engineering Institute, Kyungpook National University, ²Department of Pharmacology, School of Dentistry and Brain Science and Engineering Institute, Kyungpook National University, ³Department of Pharmacology, School of Medicine and Brain Science and Engineering Institute, Kyungpook National University

Traditional head fixation techniques have used metallic frames attached on the skull as an interface for head fixation apparatus. This protocol demonstrates a frameless, acrylic resin molding based head fixation technique for behavioral tasks in rodents.

Chemistry

An Optimized Protocol for the Efficient Radiolabeling of Gold Nanoparticles by Using a ¹²⁵I-labeled Azide Prosthetic Group

Jongho Jeon^1,2, Ha Eun Shim¹, Sajid Mushtaq^1,2, Mi Hee Choi¹, Sang Hyun Park^1,2, Dae Seong Choi¹, Beom-Su Jang^1,2

¹Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, ²Department of Radiation Biotechnology and Applied Radioisotope Science, University of Science and Technology

A detailed procedure for the synthesis of a ¹²⁵I-labeled azide and the radiolabeling of dibenzocyclooctyne (DBCO)-group-conjugated, 13-nm-sized gold nanoparticles using a copper-free click reaction is described.

Engineering

An Efficient Method for Selective Desalination of Radioactive Iodine Anions by Using Gold Nanoparticles-Embedded Membrane Filter

Ha Eun Shim^*1,2, Sajid Mushtaq^*1,3, Jongho Jeon^1,3

¹Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, ²Department of Chemistry, Kyungpook National University, ³Department of Radiation Biotechnology and Applied Radioisotope Science, University of Science and Technology

An efficient method for the rapid and ion-selective desalination of radioactive iodine in several aqueous solutions is described by using gold nanoparticles-immobilized cellulose acetate membrane filters.

Neuroscience

Three-Dimensional Shape Modeling and Analysis of Brain Structures

Jaeil Kim¹, Maria del Carmen Valdés Hernández², Jinah Park³

¹School of Computer Science and Engineering, Kyungpook National University, ²Centre for Clinical Brain Sciences, University of Edinburgh, ³School of Computing and KI for Health Science and Technology (KIHST), Korea Advanced Institute of Science and Technology (KAIST)

We introduce a semi-automatic protocol for shape analysis on brain structures, including image segmentation using open software, and further group-wise shape analysis using an automated modeling package. Here, we demonstrate each step of the 3D shape analysis protocol with hippocampal segmentation from brain MR images.