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2 ARTICLES PUBLISHED IN JoVE

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Chemistry

Exfoliation and Analysis of Large-area, Air-Sensitive Two-Dimensional Materials
Josh P. Thompson 1, M. Hasan Doha 1, Peter Murphy 1,2, Jin Hu 1,3, Hugh O.H. Churchill 1,3
1Department of Physics, University of Arkansas, 2Department of Physics, SUNY Geneseo, 3Institute for Nanoscale Science and Engineering, University of Arkansas

A method for exfoliating large thin flakes of air sensitive two-dimensional materials and safely transporting them for analysis outside of a glovebox is presented.

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Biochemistry

The Automated Crystallography Pipelines at the EMBL HTX Facility in Grenoble
Irina Cornaciu 1,2, Raphael Bourgeas 1, Guillaume Hoffmann 1, Florine Dupeux 1,3, Anne-Sophie Humm 1, Vincent Mariaule 1, Andrea Pica 1,2, Damien Clavel 1,2, Gael Seroul 1,2, Peter Murphy 1, José Antonio Márquez 1,2
1European Molecular Biology Laboratory, 2ALPX S.A.S., 3Institut de Biologie Structurale

Here, we describe how to use the automated macromolecular crystallography pipelines for protein-to-structure, rapid ligand-protein complex analysis and large-scale fragment screening based on the CrystalDirect technology at the HTX Laboratory in EMBL Grenoble.

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