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Swedish Medical Center

2 ARTICLES PUBLISHED IN JoVE

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Biology

Imaging of Estrogen Receptor-α in Rat Pial Arterioles using a Digital Immunofluorescent Microscope
Niloofar Rezvani 1, Andrei V. Blokhin 1, Emil Zeynalov 1, Marguerite T. Littleton-Kearney 1
1Graduate School of Nursing, Uniformed Services University of the Health Sciences

The goal of this article is to demonstrate a method to optimize immunofluorescent detection of estrogen receptor-α (ERα) in rat pial arterial slices using a digital immunofluorescent microscope.

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Medicine

Continuous IV Infusion is the Choice Treatment Route for Arginine-vasopressin Receptor Blocker Conivaptan in Mice to Study Stroke-evoked Brain Edema
Emil Zeynalov 1, Susan M. Jones 1, J. Paul Elliott 2
1Neurotrauma Research, Swedish Medical Center, 2Neurosurgery, Colorado Brain and Spine Institute

Our studies have revealed that the beneficial effects of conivaptan are dependent on the method of delivery after experimental stroke in mice. We have developed a research protocol for delivery of the receptor blocker via IV catheter on stroke-evoked brain edema formation in mice.

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