Swedish Medical Center

3 ARTICLES PUBLISHED IN JoVE

Biology

Imaging of Estrogen Receptor-α in Rat Pial Arterioles using a Digital Immunofluorescent Microscope

Niloofar Rezvani¹, Andrei V. Blokhin¹, Emil Zeynalov¹, Marguerite T. Littleton-Kearney¹

¹Graduate School of Nursing, Uniformed Services University of the Health Sciences

The goal of this article is to demonstrate a method to optimize immunofluorescent detection of estrogen receptor-α (ERα) in rat pial arterial slices using a digital immunofluorescent microscope.

Medicine

Continuous IV Infusion is the Choice Treatment Route for Arginine-vasopressin Receptor Blocker Conivaptan in Mice to Study Stroke-evoked Brain Edema

Emil Zeynalov¹, Susan M. Jones¹, J. Paul Elliott²

¹Neurotrauma Research, Swedish Medical Center, ²Neurosurgery, Colorado Brain and Spine Institute

Our studies have revealed that the beneficial effects of conivaptan are dependent on the method of delivery after experimental stroke in mice. We have developed a research protocol for delivery of the receptor blocker via IV catheter on stroke-evoked brain edema formation in mice.

Medicine

Surgical Approach and Complications of Stand-alone Lateral Trans-Psoas Interbody Fusion

Julius Gerstmeyer^1,2,3, Periklis Godolias⁴, Thomas A. Schildhauer⁵, Clifford Pierre^1,2, Neel Patel^1,2, Donald David Davis^1,2,5, Bryan Anderson^1,2,5, Amir Abdul-Jabbar¹, Jens R. Chapman¹, Rod J. Oskouian¹

¹Swedish Neuroscience Institute, Swedish Medical Center, ²Seattle Science Foundation, ³Department of Orthopedics and Trauma Surgery, BG University Hospital Bergmannsheil, Ruhr University Bochum, ⁴Department of Orthopedics and Trauma Surgery, St. Josef Hospital Essen-Werden, ⁵Orthopaedic Institute of Southern Illinois

Interbody fusion of the lumbar spine can be achieved surgically using different techniques. Minimally invasive techniques, including lateral interbody fusion, have been developed within recent decades to reduce rates of complications and allow for quicker patient recovery. We provide insight into stand-alone lateral trans-psoas interbody fusion, highlighting potential complications and pitfalls.