Missouri State University
2 ARTICLES PUBLISHED IN JoVE
Chemistry
Synthesis of Cd-free InP/ZnS Quantum Dots Suitable for Biomedical Applications
Matthew A. Ellis 1, Giovanna Grandinetti 2, Katye M. Fichter 1
1Department of Chemistry, Missouri State University, 2Center for Molecular Microscopy, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research
In this protocol, the synthesis of Cd-free InP/ZnS quantum dots (QDs) is detailed. InP-based QDs are gaining popularity due to the toxicity of Cd2+ ions that may be released through nanoparticle degradation. After synthesis, QDs are solubilized in water using an amphiphilic polymer for use in biomedical applications.
Labeling Neuronal Morphology Using Custom Diolistic Techniques
Lyon Hough 1, Michael E. Brown 2
1Department of Biomedical Sciences, Missouri State University, 2Department of Pathology, Saint Louis University School of Medicine
Here, we present a protocol for custom diolistic labeling. The customization of this fluorescent neuronal labeling method provides a modifiable technique that can be adapted to a wide variety of research goals and applications in the analysis of neuronal morphology.
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