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Missouri State University

2 ARTICLES PUBLISHED IN JoVE

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Chemistry

Synthesis of Cd-free InP/ZnS Quantum Dots Suitable for Biomedical Applications
Matthew A. Ellis 1, Giovanna Grandinetti 2, Katye M. Fichter 1
1Department of Chemistry, Missouri State University, 2Center for Molecular Microscopy, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research

In this protocol, the synthesis of Cd-free InP/ZnS quantum dots (QDs) is detailed. InP-based QDs are gaining popularity due to the toxicity of Cd2+ ions that may be released through nanoparticle degradation. After synthesis, QDs are solubilized in water using an amphiphilic polymer for use in biomedical applications.

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Labeling Neuronal Morphology Using Custom Diolistic Techniques
Lyon Hough 1, Michael E. Brown 2
1Department of Biomedical Sciences, Missouri State University, 2Department of Pathology, Saint Louis University School of Medicine

Here, we present a protocol for custom diolistic labeling. The customization of this fluorescent neuronal labeling method provides a modifiable technique that can be adapted to a wide variety of research goals and applications in the analysis of neuronal morphology.

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