Chang-Gung University College of Medicine
2 ARTICLES PUBLISHED IN JoVE
Immunology and Infection
Murine Full-thickness Skin Transplantation
Chih-Hsien Cheng *1,2, Chen-Fang Lee *1,2, Madeline Fryer *3, Georg J. Furtmüller 3, Byoungchol Oh 3, Jonathan D. Powell 1, Gerald Brandacher 3
1Sidney-Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, 2Department of Liver and Transplantation Surgery, Chang-Gung Transplantation Institute, Chang-Gung Memorial Hospital, Chang-Gung University College of Medicine, 3Vascularized Composite Allotransplantation Laboratory, Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine
Murine full-thickness skin transplantation is a well-established model to study rejection in an alloimmune setting. Here, we provide a tutorial of each step involved in performing a BALB/c-->C57BL/6 full-thickness skin transplant.
Medicine
Ex Vivo and In Vivo Animal Models for Mechanical and Chemical Injuries of Corneal Epithelium
Kuo Hsuan Hung 1,2,3, Lung Kun Yeh 1,2
1Department of Ophthalmology, Chang-Gung Memorial Hospital, 2Chang-Gung University College of Medicine, 3Institute of Clinical Medicine, National Yang Ming Chiao Tung University
Here, animal models based on mouse and rabbit are developed for mechanical and chemical injury of corneal epithelium to screen new therapeutics and the underlying mechanism.
