NYU Grossman School of Medicine
2 ARTICLES PUBLISHED IN JoVE
Cancer Research
A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
Arman Alberto Sorin Shadaloey 1,2, Alcida Karz 1,2, Rana S. Moubarak 1,2, Praveen Agrawal 1,2, Grace Levinson 1,2, Kevin Kleffman 1,2, Orlando Aristizabal 3,4, Iman Osman 2,5, Youssef Z. Wadghiri 3,4, Eva Hernando 1,2
1Department of Pathology, NYU Grossman School of Medicine, 2Interdisciplinary Melanoma Cooperative Group, Perlmutter Cancer Center, 3Department of Radiology, NYU Grossman School of Medicine, 4Preclinical Imaging Core, NYU Grossman School of Medicine, 5Ronald Perelman Department of Dermatology, NYU Grossman School of Medicine
This article describes a workflow of techniques employed for testing novel candidate mediators of melanoma metastasis and their mechanism(s) of action.
Biology
Visualizing Single-Stranded DNA Foci in the G1 Phase of the Cell Cycle
Qingyue Zhang 1,2, Marc A. Kerzhnerman 1,2, Nelson García-Vázquez 1,2,3, Gergely Rona 1,2,4,5
1Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, 2The Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, 3Department of Cell Biology, NYU Grossman School of Medicine, 4Howard Hughes Medical Institute, NYU Grossman School of Medicine, 5Institute of Enzymology, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN Research Centre for Natural Sciences
The following protocol presents the detection of single-stranded DNA foci in the G1 phase of the cell cycle utilizing cell cycle synchronization followed by RPA2 immunofluorescent staining.
