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Chapter 6

Drugs Acting on Autonomic Nervous System: Adrenergic Agonists and Antagonists Agents

肾上腺素能神经元:神经传递
肾上腺素能神经元:神经传递
Postganglionic sympathetic fibers (except those supplying the sweat glands) releasing noradrenaline or norepinephrine are called noradrenergic or ...
肾上腺素能受体(Adrenoceptors):分类
肾上腺素能受体(Adrenoceptors):分类
Adrenergic receptors, or adrenoceptors, respond to the autonomic neurotransmitter noradrenaline and other endogenous catecholamine agonists. They are ...
肾上腺素能受体: ɑ 亚型
肾上腺素能受体: ɑ 亚型
Adrenoceptors are classified into α and ꞵ classes based on their potencies to catecholamine agonists. α-adrenoceptors show the following ...
肾上腺素能受体:β 亚型
肾上腺素能受体:β 亚型
β-adrenoceptors have varied sensitivities towards adrenaline, noradrenaline, and isoprenaline. The order of agonist potency is as follows: ...
肾上腺素能激动剂:直接作用剂
肾上腺素能激动剂:直接作用剂
Drugs that mimic the action of endogenous catecholamines like noradrenaline and adrenaline are called adrenergic agonists or sympathomimetics. Based on ...
肾上腺素能激动剂:间接作用剂
肾上腺素能激动剂:间接作用剂
Indirect-acting adrenergic agonists potentiate the effects of endogenous catecholamines through different mechanisms without directly binding to ...
肾上腺素能激动剂:混合作用剂
肾上腺素能激动剂:混合作用剂
Mixed-action adrenergic agonists, like ephedrine and pseudoephedrine, directly and indirectly affect adrenergic receptors. These agents stimulate ...
肾上腺素能激动剂:化学和构效关系
肾上腺素能激动剂:化学和构效关系
Adrenergic agonists' structure-activity relationship (SAR) determines their selectivity and efficacy. These agonists comprise a phenylethylamine ...
肾上腺素能激动剂的治疗分类
肾上腺素能激动剂的治疗分类
Adrenergic agonists can be classified based on their therapeutic uses and mechanisms of action. They serve various purposes in clinical applications. ...
肾上腺素能激动剂:治疗用途
肾上腺素能激动剂:治疗用途
Adrenergic agonists have diverse therapeutic uses across various medical conditions and emergencies. Emergency and Intensive Care Unit (ICU) applications: ...
肾上腺素能拮抗剂: ɑ 受体阻滞剂的化学和分类
肾上腺素能拮抗剂: ɑ 受体阻滞剂的化学和分类
Adrenergic antagonists, or sympatholytics, inhibit adrenoceptor activation driven by catecholamines or agonists. Based on their adrenoceptor specificity, ...
肾上腺素能拮抗剂: ɑ-受体阻滞剂的药理作用
肾上腺素能拮抗剂: ɑ-受体阻滞剂的药理作用
α-Adrenergic antagonists, known as α-blockers, exert their effects by inhibiting α-adrenoceptors, leading to specific physiological ...
肾上腺素能拮抗剂的化学和 β 受体阻滞剂的分类
肾上腺素能拮抗剂的化学和 β 受体阻滞剂的分类
β-adrenergic antagonists, or β-blockers, modulate the sympathetic nervous system by targeting β-adrenoceptors and inhibiting ...
肾上腺素能拮抗剂: β受体阻滞剂的药理作用
肾上腺素能拮抗剂: β受体阻滞剂的药理作用
β-receptor blockers significantly impact the cardiovascular system by counteracting catecholamine-induced sympathetic responses. These medications ...
肾上腺素能拮抗剂:ɑ 和 β 受体阻滞剂
肾上腺素能拮抗剂:ɑ 和 β 受体阻滞剂
Third-generation β-blockers, such as labetalol and carvedilol, represent a significant advancement in managing cardiovascular conditions. Unlike ...
影响神经递质合成的药物
影响神经递质合成的药物
Drugs affecting neurotransmitter synthesis can impact the adrenergic neuron and the synthesis of neurotransmitters. For example, α-methyltyrosine and ...
影响神经递质释放或摄取的药物
影响神经递质释放或摄取的药物
Certain drugs can affect how neurotransmitters called catecholamines, are released or taken back up in the adrenergic neuron. They can have different ...
青光眼:概述
青光眼:概述
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if ...
开角型青光眼:治疗
开角型青光眼:治疗
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This ...
闭角型青光眼:治疗
闭角型青光眼:治疗
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup ...
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