Chapter 6
Drugs Acting on Autonomic Nervous System: Adrenergic Agonists and Antagonists Agents
Neuroni adrenergici: neurotrasmissione
Postganglionic sympathetic fibers (except those supplying the sweat glands) releasing noradrenaline or norepinephrine are called noradrenergic or ...
Recettori adrenergici (Adrenocettori): Classificazione
Adrenergic receptors, or adrenoceptors, respond to the autonomic neurotransmitter noradrenaline and other endogenous catecholamine agonists. They are ...
Recettori adrenergici: ɑ Sottotipo
Adrenoceptors are classified into α and ꞵ classes based on their potencies to catecholamine agonists. α-adrenoceptors show the following ...
Recettori adrenergici: sottotipo β
β-adrenoceptors have varied sensitivities towards adrenaline, noradrenaline, and isoprenaline. The order of agonist potency is as follows:
...
Agonisti adrenergici: agenti ad azione diretta
Drugs that mimic the action of endogenous catecholamines like noradrenaline and adrenaline are called adrenergic agonists or sympathomimetics. Based on ...
Agonisti adrenergici: agenti ad azione indiretta
Indirect-acting adrenergic agonists potentiate the effects of endogenous catecholamines through different mechanisms without directly binding to ...
Agonisti adrenergici: agenti ad azione mista
Mixed-action adrenergic agonists, like ephedrine and pseudoephedrine, directly and indirectly affect adrenergic receptors. These agents stimulate ...
Agonisti adrenergici: chimica e relazione struttura-attività
Adrenergic agonists' structure-activity relationship (SAR) determines their selectivity and efficacy. These agonists comprise a phenylethylamine ...
Agonisti adrenergici: classificazione terapeutica
Adrenergic agonists can be classified based on their therapeutic uses and mechanisms of action. They serve various purposes in clinical applications.
...
Agonisti adrenergici: usi terapeutici
Adrenergic agonists have diverse therapeutic uses across various medical conditions and emergencies.
Emergency and Intensive Care Unit (ICU) applications: ...
Antagonisti adrenergici: chimica e classificazione dei bloccanti del recettore ɑ
Adrenergic antagonists, or sympatholytics, inhibit adrenoceptor activation driven by catecholamines or agonists. Based on their adrenoceptor specificity, ...
Antagonisti adrenergici: azioni farmacologiche dei bloccanti del recettore ɑ
α-Adrenergic antagonists, known as α-blockers, exert their effects by inhibiting α-adrenoceptors, leading to specific physiological ...
Antagonisti adrenergici: chimica e classificazione dei bloccanti del β-recettore
β-adrenergic antagonists, or β-blockers, modulate the sympathetic nervous system by targeting β-adrenoceptors and inhibiting ...
Antagonisti adrenergici: azioni farmacologiche dei bloccanti del β-recettore
β-receptor blockers significantly impact the cardiovascular system by counteracting catecholamine-induced sympathetic responses. These medications ...
Antagonisti adrenergici: ɑ e bloccanti dei recettori β
Third-generation β-blockers, such as labetalol and carvedilol, represent a significant advancement in managing cardiovascular conditions. Unlike ...
Farmaci che influenzano la sintesi dei neurotrasmettitori
Drugs affecting neurotransmitter synthesis can impact the adrenergic neuron and the synthesis of neurotransmitters. For example, α-methyltyrosine and ...
Farmaci che influenzano il rilascio o l'assorbimento dei neurotrasmettitori
Certain drugs can affect how neurotransmitters called catecholamines, are released or taken back up in the adrenergic neuron. They can have different ...
Glaucoma: Panoramica
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if ...
Glaucoma ad angolo aperto: trattamento
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This ...
Glaucoma ad angolo chiuso: trattamento
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup ...
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