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Chapter 17

Pharmacotherapy of the Epilepsies

下肢动脉
下肢动脉
Epilepsy is a chronic neurological disorder characterized by recurrent, unpredictable seizures. Seizures result from abnormal electrical discharges in the ...
癫痫发作:分类
癫痫发作:分类
Epilepsy is a chronic neurological disorder characterized by unpredictable seizures. Seizures can be provoked by identifiable factors or occur ...
抗癫痫药物:钠通道阻滞剂
抗癫痫药物:钠通道阻滞剂
Antiepileptic drugs, essential in managing epilepsy, effectively prevent seizures by blocking the movement of sodium ions through channels in the ...
抗癫痫药物:GABA能途径增强剂
抗癫痫药物:GABA能途径增强剂
γ-aminobutyric acid or GABA pathway potentiators are drugs used to manage epilepsy by enhancing GABA neurotransmission, a critical inhibitory pathway ...
抗癫痫药物:钙通道阻滞剂
抗癫痫药物:钙通道阻滞剂
Calcium channel blockers, primarily known for cardiovascular use, have also shown potential as antiepileptic drugs. They exert their effects by modulating ...
抗癫痫药物:谷氨酸拮抗剂
抗癫痫药物:谷氨酸拮抗剂
Glutamate is the primary excitatory neurotransmitter in the brain, essential for neuronal communication. It plays a crucial role in synaptic transmission, ...
抗癫痫药物: SV2A 蛋白介导的神经递质释放调节剂
抗癫痫药物: SV2A 蛋白介导的神经递质释放调节剂
Antiepileptic drugs, like levetiracetam and brivaracetam, leverage the synaptic vesicle protein SV2A to mitigate seizures. SV2A is a transmembrane ...
抗癫痫药物:钾通道激活剂
抗癫痫药物:钾通道激活剂
The Antiepileptic drug ezogabine functions as a potassium channel activator by enhancing transmembrane potassium currents mediated by the KCNQ subtype of ...
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