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A Simple Bioassay for the Evaluation of Vascular Endothelial Growth Factors

DOI :

10.3791/53867-v

March 15th, 2016

March 15th, 2016

9,500 Views

1Tumour Angiogenesis Program, Peter MacCallum Cancer Centre

We describe a simple cell-based bioassay for detecting, quantifying and monitoring the activity of members of the vascular endothelial growth factor family of ligands. The assay uses chimeric receptors expressed in a factor-dependent cell line to provide a semi-quantitative or quantitative assessment of receptor binding and cross-linking by the ligand.

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Simple Bioassay

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