Name: synthesis of plant phenol-derived polymeric dyes for direct or mordant-based hair dyeing
Uploaded: 2016-12-01T12:00:00.000+00:00
Duration: 9 min 46 s
Description: Watch this Scientific Journal Video about Synthesis of Plant Phenol-derived Polymeric Dyes for Direct or Mordant-based Hair Dyeing at JoVE.com

This work was supported by the New Professor Research Foundation Program, funded by Gyeongsang National University (Grant Number 2015-04-020).

1.植物苯酚衍生的高分子染料的制备<ol><li> 32毫升的100mM乙酸钠缓冲液（pH5.0）和8毫升无水乙醇中的儿茶素水合物（0.1克） - 溶解儿茶酚（0.1克）和（+）。 </li><li>添加10毫克的T.云芝漆酶的catechol-和含儿茶素的缓冲区。混合大力和将溶液倒入方形培养皿。在室温下孵育皿在24小时的振荡培养箱（25转）。从透明的暗黑色溶液的显着的颜色变化可以用肉眼漆酶诱导的偶合反应之后观察到。 </li><li>离心溶液10分钟以20,000 xg离心以降速不溶的聚合物颗粒。使用进一步的脱盐深黑上清。 </li><li>脱盐用5 kDa的超滤光盘反应溶液中。浓缩反应体积至20ml通过超滤后，通过加入300毫升蒸馏水交换反应缓冲液。最后，使用过滤，浓缩溶液的体积至25ml。 </li></ol> 2.灰色头发角蛋白染色解决方案<ol><li>准备以下六个聚合物溶液:聚合物染料，聚合物染料/ 硫酸亚铁，聚合物染料/ 硫酸亚铁在pH为3的水，聚合物染料/ 硫酸亚铁在pH为11的水，聚合物染料/ 硫酸亚铁用乙酸，和聚合物染料/硫酸亚铁4与氨。 <ol><li>为聚合染料，混合溶于5ml蒸馏水用1ml脱盐聚合物染料（1.4）的。 </li><li>为媒染剂溶液，从步骤2.1.1添加0.33克的FeSO 4的混合物中。大力涡旋溶解硫酸亚铁完全。 </li><li>对于pH为3或11的水溶液，调整用1N HCl或1N的NaOH5毫升蒸馏水的pH值。再加入1毫升脱盐聚合染料（1.4）和0.33克硫酸亚铁的。 </li><li>对于乙酸 - 或氨处理的溶液，混匀1.0毫升GL的acial乙酸或1.0毫升氨水用5ml蒸馏水。再加入1毫升脱盐聚合染料（1.4）和0.33克硫酸亚铁的。 </li></ol></li><li>于6ml蒸馏水中，有或没有0.33克的FeSO 4的儿茶素水合物（0.1克），浸泡在头发-为对植物的单体，混合邻苯二酚（0.1克）和（+）。 </li><li>如从步骤2.1和2.2的染色溶液制备不久，完全浸泡在溶液5厘米长的灰色人发束（0.2克）。孵育在32℃的发束在2.5小时的摇动培养箱（160转）。 </li><li>此后，取出发束，用流水冲洗。使用电子头发干燥器以除去水分。引起的聚合物染料颜色变化可以用肉眼可视化。 <ol><li>以获得颜色参数（ 即，L *，a *和b *的 ），使用根据制造商的协议的常规色度计。揉碎头发Ťresses成一团，从而使他们能够用比色计的透镜来测量。重复在毛发上与色度计透镜的不同区域这一过程。 </li><li>测量每个染色发辫七倍的颜色参数。计算平均值和所述参数的标准偏差。使用下式计算ΔE:[（100 - L *）2 +（A *）2 +（B *）2] 1/2。 </li></ol></li></ol> 3.颜色耐久性试验<ol><li>在40毫升的蒸馏水中溶解200毫克十二烷基硫酸钠（SDS）的。完全浸泡染发在含有SDS的水，在室温下5分钟。取出发束，然后用足够的自来水冲洗一下，以除去洗涤剂。使用电子头发干燥器以除去水分。 </li><li>以获得颜色参数（ 即，L *，a *和b *的 ），采用根据厂家专业的常规色度计呃的协议。重复步骤3.1与同染发描述再次浸泡，然后再测量参数。 </li><li>溶解800毫克的SDS在40毫升的蒸馏水。如步骤3.1中所述，多重复用相同的染发浸泡两次。总体而言，共四次对待每染发束用SDS溶液。 </li></ol>

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The authors declare that they have no competing financial interests.

有趣的是，我们的方法减少花染的头发角蛋白具有天然酚类物质氧化引起的聚合反应的时间。它还通过聚合物染料的简单的操作，如改变pH值和施加媒染剂诱导的毛发颜色多样。 在头发角蛋白与植物酚类的漆酶催化氧化的原位培养过于需要很长的培育时间以达到有效的染色7。这种缓染动力学可能是由于植物酚类的差结合能力，并具有非常低的分子量，?...

漆酶是氧化酶是对酚和多酚化合物的活性。他们已经在各种生物体，包括植物，真菌，昆虫和细菌被确定。他们的行动酶有助于几种形态的现象1。酶催化底物的单电子氧化，导致在被进一步耦合到小的有机物和固体表面自由基的形成。这种耦合过程导致的低聚物和聚合物的合成和表面functionalizations 2,3。当漆酶底物是从天然来源，如植物酚类，酶促反应是相对于绿色化学的极大兴趣。这里，两种反应物和催化剂是从天然来源。此外，所得到的产品类似于天然产物，因为整个反应模拟天然酚的体内合成聚合物，包括植物木质素，聚（flavono编号），和腐殖质其中小植物酚类化合物是高度交联通过氧化酶诱导的自由基偶合4。 从植物衍生的酚的漆酶催化的偶联反应衍生的产品可以用于通过原位孵育染灰发，并且可以开发作为替代市售染料1。这样的替代是重要的，因为是基于对苯二胺（PPD）商业染发剂，PPD相关二胺化合物，以及过氧化氢，这已被证明是有毒的，致癌和过敏人类5,6在漆酶催化的偶联反应中，漆酶和植物酚类功能替换分别过氧化氢和对苯二胺，7。但是，基于漆酶系统的染色速度比商用一个慢得多。在一般情况下，基于PPD-染色剂需要不到一小时，以实现在角蛋白毛发有效的颜色变化，而基于漆酶反应需要过夜温育7。缓慢染色动力学可以通过两种可能的现象进行说明。第一，使用低pH值缓冲液（ 例如，pH值为5），以最大限度地提高漆酶活性已被观察到降低在角蛋白基质溶胀，从而抑制染料成矩阵的深穿透程度。实际上，代理允许染色反应在高pH条件下进行已被证明是不可或缺的商用头发染色产品8。其次，聚合反应过程中表现出很强的吸附到角质表面可能发色团分子的数量已经被证明是成比例的孵育时间（ 即，聚合的程度）。例如，多巴胺聚多巴胺的转化显示出诱导到许多表面，这是伴随着黑色9的形成强粘合力。&lt;/ P&gt; 在目前的工作中，预合成由T.获得的聚合物产品云芝儿茶素和儿茶酚的漆酶催化氧化反应被用来治疗头发角蛋白染色。我们推测的聚合物的吸附能力将比单体植物酚的强得多，他们将最初形成的低分子量的低聚物。结果表明，使用预先合成的聚合物时，酶促氧化电源不再需要。这表明，pH值可被控制，并且金属离子可以染发处理中使用，而不管酶的活性。这个协议提供了一个简单而快速的方法，同时使用生态友好的和可再生的来自植物的酚（ 图1）的染料在颜色的各种色调角蛋白毛发。

<table><tbody><tr><td>Sodium dodecyl Sulfate</td><td>Promega</td><td>H5114</td><td></td></tr><tr><td>Laccase from Trametes versicolor</td><td>Sigma</td><td>38429-1G</td><td>Enzyme activity is denoted as 0.53 U/mg</td></tr><tr><td>(+)-catechin hydrate</td><td>Sigma</td><td>C1251-5G</td><td></td></tr><tr><td>1,2-dihydroxybenzene (catechol)</td><td>Sigma</td><td>135011-5G</td><td></td></tr><tr><td>Ammonia water&amp;nbsp;</td><td>Duksan</td><td>701</td><td>Ammonia contents is denoted as 25 ~ 30%</td></tr><tr><td>Acetic acid, glacial</td><td>Duksan</td><td>448</td><td></td></tr><tr><td>Iron(II) sulfate heptahydrate</td><td>JUNSEI</td><td>83380-1250</td><td></td></tr><tr><td>Ultracell 5 kDa</td><td>Amicon</td><td>PLCC06210</td><td></td></tr><tr><td>Stirred ultrafiltration cells</td><td>Millipore</td><td>Model 8200</td><td></td></tr><tr><td>Human gray hair</td><td>PheonixKorea</td><td>Not available</td><td></td></tr><tr><td>Colorimeter</td><td>SPEC</td><td>JCS-10</td><td></td></tr><tr><td>Square dish</td><td>SPL</td><td>10125</td><td>125 * 125 * 20 (mm)</td></tr></tbody></table>

synthesis of plant phenol-derived polymeric dyes for direct or mordant-based hair dyeing

有效的头发染色通过在角蛋白毛发与植物酚的真菌漆酶催化的聚合的产物的原位孵育先前已经证明。然而，染色过程需要较长的时间相比，商业的染发产品来完成。为了克服这一瓶颈，预先合成的栓的云芝上儿茶素和儿茶酚漆酶氧化反应的聚合物产品，无论是有或没有媒剂（ 例如， 硫酸亚铁），这里被用来实现永久角蛋白毛发染色的各种颜色和色调。在酸性醋酸钠缓冲液漆酶耦合作用厂酚之间的反应后，导致了深黑的颜色。然后将着色染料产物脱盐并浓缩，之后用超滤。染料，有或没有媒剂，导致在灰色人类头发的WiΔE值（ 即，色差值）显著增加薄2.5小时。此外，不同的角蛋白颜色和色调取决于媒染和pH值的变化被诱导。染色的毛发还表现出对洗涤剂处理有很强的抵抗力，表明我们的方法可以产生永久染发。总的来说，我们的工作提供了新颖的洞察显影生态友好的染发方法以替代商业有毒二胺类染料。

首先，聚合物染料的染色能力相比，来自植物的单体（ 即，儿茶素和儿茶酚）的。的聚合物染料诱导的灰色角蛋白毛发（ 图2A和图3）的颜色显著变化，而头发的先天灰色保持与植物的单体非常稳定的（ 数据未显示 ）。然后媒染对聚合物产品的染色能力剂的作用进行了评价。如在图2A中看到的，除了Fe离子导致的灰...

Watch this Scientific Journal Video about Synthesis of Plant Phenol-derived Polymeric Dyes for Direct or Mordant-based Hair Dyeing at JoVE.com

Synthesis of Plant Phenol-derived Polymeric Dyes for Direct or Mordant-based Hair Dyeing

Here, we present a protocol to use pre-synthesized polymeric products derived from fungal laccase-catalyzed polymerization of plant phenols, either with or without mordant agents (e.g., FeSO4), to induce detergent-resistant keratin hair dyeing within 2.5 hours.

对于直接或媒介为基础的头发染色厂苯酚衍生的高分子染料的合成

Effective hair dyeing through in situ incubation of keratin hair with the products of fungal laccase-catalyzed polymerization of plant phenols has been ...

synthesis-plant-phenol-derived-polymeric-dyes-for-direct-or-mordant

Research

JoVE Journal

Chemistry

9.2K 次观看.  Gyeongsang National University. Here, we present a protocol to use pre-synthesized polymeric products derived from fungal laccase-catalyzed polymerization of plant phenols, either with or without mordant agents (e.g., FeSO4), to induce detergent-resistant keratin hair dyeing within 2.5 hours.

视频: Synthesis of Plant Phenol-derived Polymeric Dyes for Direct or Mordant-based Hair Dyeing

Microwave-assisted Intramolecular Dehydrogenative Diels-Alder Reactions for the Synthesis of Functionalized Naphthalenes/Solvatochromic Dyes

Functionalized naphthalenes have applications in a variety of research fields ranging from the synthesis of natural or biologically active molecules to the preparation of new organic dyes. Although numerous strategies have been reported to access naphthalene scaffolds, many procedures still present limitations in terms of incorporating functionality, which in turn narrows the range of available substrates. The development of versatile methods for direct access to substituted naphthalenes is therefore highly desirable.
The Diels-Alder (DA) cycloaddition reaction is a powerful and attractive method for the formation of saturated and unsaturated ring systems from readily available starting materials. A new microwave-assisted intramolecular dehydrogenative DA reaction of styrenyl derivatives described herein generates a variety of functionalized cyclopenta[b]naphthalenes that could not be prepared using existing synthetic methods. When compared to conventional heating, microwave irradiation accelerates reaction rates, enhances yields, and limits the formation of undesired byproducts.
The utility of this protocol is further demonstrated by the conversion of a DA cycloadduct into a novel solvatochromic fluorescent dye via a Buchwald-Hartwig palladium-catalyzed cross-coupling reaction. Fluorescence spectroscopy, as an informative and sensitive analytical technique, plays a key role in research fields including environmental science, medicine, pharmacology, and cellular biology. Access to a variety of new organic fluorophores provided by the microwave-assisted dehydrogenative DA reaction allows for further advancement in these fields.

Microwave-assisted intramolecular dehydrogenative Diels-Alder (DA) reactions provide concise access to functionalized cyclopenta[b]naphthalene building blocks. The utility of this methodology is demonstrated by one-step conversion of the dehydrogenative DA cycloadducts into novel solvatochromic fluorescent dyes via Buchwald-Hartwig palladium-catalyzed cross-coupling reactions.

微波辅助分子内Diels-Alder反应的功能化萘/变色染料的合成脱氢

Functionalized naphthalenes have applications in a variety of research fields ranging from the synthesis of natural or biologically active molecules to ...

科研

化学

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles

In this protocol, we first describe a procedure to synthesize lanthanide doped upconverting nanoparticles (UCNPs). We then demonstrate how to generate amphiphilic polymers in situ, and describe a protocol to encapsulate the prepared UCNPs and different organic dye molecules (porphyrins and diarylethenes) using polymer shells to form stable water-dispersible nanoassemblies. The nanoassembly samples containing both the UCNPs and the diarylethene organic dyes have interesting photochemical and photophysical properties. Upon 365 nm UV irradiation, the diarylethene group undergoes a visual color change. When the samples are irradiated with visible light of another specific wavelength, the color fades and the samples return to the initial colorless state. The samples also emit visible light from the UCNPs upon irradiation with 980 nm near-infrared light. The emission intensity of the samples can be tuned through alternate irradiation with UV and visible light. Modulation of fluorescence can be performed for many cycles without observable degradation of the samples. This versatile encapsulation procedure allows for the transfer of hydrophobic molecules and nanoparticles from an organic solvent to an aqueous medium. The polymer helps to maintain a lipid-like microenvironment for the organic molecules to aid in preservation of their photochemical behavior in water. Thus this method is ideal to prepare water-dispersible photoresponsive systems. The use of near-infrared light to activate upconverting nanoparticles allows for lower energy light to be used to activate photoreactions instead of more harmful ultraviolet light.

Organic dye molecules and oleic acid coated upconverting nanoparticles are not water-soluble. This protocol describes a &#8216;plug and play&#8217; method that enables the transfer of organic dye molecules and upconverting particles from their initial hydrophobic solvent to water.

A&#39;即插即用&#39;的方法来创建水分散性Nanoassemblies包含两亲聚合物，有机染料和上变频纳米粒子

In this protocol, we first describe a procedure to synthesize lanthanide doped upconverting nanoparticles (UCNPs). We then demonstrate how to generate ...

Ethylene Polymerizations Using Parallel Pressure Reactors and a Kinetic Analysis of Chain Transfer Polymerization

We demonstrate a method for high-throughput catalyst screening using a parallel pressure reactor starting from the initial synthesis of a nickel &#945;-diimine ethylene polymerization catalyst. Initial polymerizations with the catalyst lead to optimized reaction conditions, including catalyst concentration, ethylene pressure and reaction time. Using gas-uptake data for these reactions, a procedure to calculate the initial rate of propagation (kp) is presented. Using the optimized conditions, the ability of the nickel &#945;-diimine polymerization catalyst to undergo chain transfer with diethylzinc (ZnEt2) during ethylene polymerization was investigated. A procedure to assess the ability of the catalyst to undergo chain transfer (from molecular weight and 13C NMR data), calculate the degree of chain transfer, and calculate chain transfer rates (ke) is presented.

A protocol for the high-throughput analysis of polymerization catalyst, chain transfer polymerizations, polyethylene characterization, and reaction kinetic analysis is presented.

乙烯聚合中使用并联电抗器的压力和链转移聚合的动力学分析

We demonstrate a method for high-throughput catalyst screening using a parallel pressure reactor starting from the initial synthesis of a nickel ...

Genetic Incorporation of Biosynthesized L-dihydroxyphenylalanine (DOPA) and Its Application to Protein Conjugation

L-dihydroxyphenylalanine (DOPA) is an amino acid found in the biosynthesis of catecholamines in animals and plants. Because of its particular biochemical properties, the amino acid has multiple uses in biochemical applications. This report describes a protocol for the genetic incorporation of biosynthesized DOPA and its application to protein conjugation. DOPA is biosynthesized by a tyrosine phenol-lyase (TPL) from catechol, pyruvate, and ammonia, and the amino acid is directly incorporated into proteins by the genetic incorporation method using an evolved aminoacyl-tRNA and aminoacyl-tRNA synthetase pair. This direct incorporation system efficiently incorporates DOPA with little incorporation of other natural amino acids and with better protein yield than the previous genetic incorporation system for DOPA. Protein conjugation with DOPA-containing proteins is efficient and site-specific and shows its usefulness for various applications. This protocol provides protein scientists with detailed procedures for the efficient biosynthesis of mutant proteins containing DOPA at desired sites and their conjugation for industrial and pharmaceutical applications.

Genetic Incorporation of Biosynthesized L-dihydroxyphenylalanine DOPA and Its Application to Protein Conjugation

Here, we present a protocol for the genetic incorporation of L-dihydroxyphenylalanine biosynthesized from simple starting materials and its application to protein conjugation.

Biosynthesized l-dihydroxyphenylalanine (多巴) 的遗传合并及其在蛋白质共轭中的应用

L-dihydroxyphenylalanine (DOPA) is an amino acid found in the biosynthesis of catecholamines in animals and plants. Because of its particular biochemical ...

生物化学

Scale-up Chemical Synthesis of Thermally-activated Delayed Fluorescence Emitters Based on the Dibenzothiophene-S,S-Dioxide Core

We report a procedure to linearly scale-up the synthesis of 2,8-bis(3,6-di-tert-butyl-9H-carbazol-9-yl)dibenzothiophene-S,S-dioxide (compound 4) and 2,8-bis(10H-phenothiazin-10-yl)dibenzothiophene-S,S-dioxide (compound 5) using Buchwald-Hartwig cross-coupling reaction conditions. In addition, we demonstrate a scaled-up synthesis of all non-commercially available starting materials that are required for the amination cross-coupling reaction. In the present article, we provide the detailed synthetic procedures for all of the described compounds, alongside their spectral characterization. This work shows the possibility to produce organic molecules for optoelectronic applications on a large scale, which facilitates their implementation into real world devices.

Scale-up synthesis of highly efficient thermally activated delayed fluorescence emitters is described in the presented article.

基于吩 s-二氧化硫核的热活化延迟荧光发射器的放大化学合成

We report a procedure to linearly scale-up the synthesis of 2,8-bis(3,6-di-tert-butyl-9H-carbazol-9-yl)dibenzothiophene-S,S-dioxide (compound 4) and ...

Using Cyclic Voltammetry, UV-Vis-NIR, and EPR Spectroelectrochemistry to Analyze Organic Compounds

Cyclic voltammetry (CV) is a technique used in the analysis of organic compounds. When this technique is combined with electron paramagnetic resonance (EPR) or ultraviolet-visible and near-infrared (UV-Vis-NIR) spectroscopies, we obtain useful information such as electron affinity, ionization potential, band-gap energies, the type of charge carriers, and degradation information that can be used to synthesize stable organic electronic devices. In this study, we present electrochemical and spectroelectrochemical methods to analyze the processes occurring in active layers of an organic device as well as the generated charge carriers.

In this article, we describe electrochemical, electron paramagnetic resonance, and ultraviolet-visible and near-infrared spectroelectrochemical methods to analyze organic compounds for application in organic electronics.

利用循环伏安法、紫外-近红外光谱和 EPR 光谱电化学对有机化合物进行分析

Cyclic voltammetry (CV) is a technique used in the analysis of organic compounds. When this technique is combined with electron paramagnetic resonance ...

Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions

The interest on nitrogen-containing heterocycles has expanded rapidly in the synthetic community since they are important motifs for new drugs. Traditionally, they were synthesized through thermal cycloaddition reactions, whereas today, photocatalysis is preferred due to the mild and efficient conditions. With this focus, a new photocatalytic method for the synthesis of nitrogen-containing heterocycles is highly desired. Here, we report a protocol for the biosynthesis of cercosporin, which could function as a metal-free photocatalyst. We then illustrate cercosporin-photocatalyzed protocols for the synthesis of nitrogen-containing heterocycles 1,2,3-thiadiazoles through annulation of azoalkenes with KSCN, and synthesis of 1,4,5,6-tetrahydropyridazines [4+2] through cyclodimerization of azoalkenes under mild conditions, respectively. As a result, there is a new bridge between the microbial fermentation method and organic synthesis in a mild, cost-effective, environmentally friendly and sustainable manner.

New routes for the synthesis of nitrogen-containing heterocycles utilizing cercosporin as a metal-free photocatalyst were developed.

神经素-光催化 [4]1]- 和 [4]2]- 在轻度条件下对阿佐尔克内斯的无效

The interest on nitrogen-containing heterocycles has expanded rapidly in the synthetic community since they are important motifs for new drugs. ...

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach

Methine-bridged conjugated bicyclic aromatic compounds are common constituents of a range of biologically relevant molecules such as porphyrins, dipyrrinones, and pharmaceuticals. Additionally, restricted rotation of these systems often results in highly to moderately fluorescent systems as observed in 3H,5H-dipyrrolo[1,2-c:2',1'-f]pyrimidin-3-ones, xanthoglows, pyrroloindolizinedione analogs, BODIPY analogs, and the phenolic and imidazolinone ring systems of Green Fluorescent Protein (GFP). This manuscript describes an inexpensive and operationally simple method of performing a Claisen-Schmidt condensation to generate a series of fluorescent pH dependent pyrazole/imidazole/isoindolone dipyrrinone analogs. While the methodology illustrates the synthesis of dipyrrinone analogs, it can be translated to produce a wide range of conjugated bicyclic aromatic compounds. The Claisen-Schmidt condensation reaction utilized in this method is limited in scope to nucleophiles and electrophiles that are enolizable under basic conditions (nucleophile component) and non-enolizable aldehydes (electrophile component). Additionally, both the nucleophilic and electrophilic reactants must contain functional groups that will not inadvertently react with hydroxide. Despite these limitations, this methodology offers access to completely novel systems that can be employed as biological or molecular probes.

The Claisen-Schmidt condensation reaction is an important methodology for the generation of methine-bridged conjugated bicyclic aromatic compounds. Through utilizing a base-mediated variant of the aldol reaction, a range of fluorescent and/or biologically relevant molecules can be accessed through a generally inexpensive and operationally simple synthetic approach.

使用克莱森-施密特凝结方法合成pH依赖皮拉佐尔、伊米达佐尔和伊森多龙二苯酮氟磷

Methine-bridged conjugated bicyclic aromatic compounds are common constituents of a range of biologically relevant molecules such as porphyrins, ...

Designed for Molecular Recycling: A Lignin-Derived Semi-aromatic Biobased Polymer

The development of chemically recyclable biopolymers offers opportunities within the pursuit of a circular economy. Chemically recyclable biopolymers make a positive effort to solve the issue of polymer materials in the disposal phase after the use phase. In this paper, the production of biobased semi-aromatic polyesters, which can be extracted entirely from biomass such as lignin, is described and visualized. The polymer poly-S described in this paper has thermal properties similar to certain commonly used plastics, such as PET. We developed a Green Knoevenagel reaction, which can efficiently produce monomers from aromatic aldehydes and malonic acid. This reaction has been proven to be scalable and has a remarkably low calculated E-factor. These polyesters with ligno-phytochemicals as a starting point show an efficient molecular recycling with minimal losses. The polyester poly(dihydrosinapinic acid) (poly-S) is presented as an example of these semi-aromatic polyesters, and the polymerization, depolymerization, and re-polymerization are described.

An example of a closed-loop approach towards a circular materials economy is described here. A whole sustainable cycle is presented where biobased semi-aromatic polyesters are designed by polymerization, depolymerization, and then re-polymerized with only slight changes in their yields or final properties.

专为分子回收而设计:一种褐宁衍生的半芳烃生物基聚合物

The development of chemically recyclable biopolymers offers opportunities within the pursuit of a circular economy. Chemically recyclable biopolymers make ...

基于多元醇的微波辅助萃取，可获得酚类和抗氧化剂的收率

Microwave-Assisted Extraction of Phenolic Compounds and Antioxidants for Cosmetic Applications Using Polyol-Based Technology

The utilization of polyols as green solvents for extracting bioactive compounds from plant materials has gained attention due to their safety and inert behavior with plant bioactive chemicals. This study explores the sustainable extraction of phenolic compounds and natural antioxidants from coffee silverskin using the microwave-assisted extraction (MAE) method with polyol-based solvents: glycerin, propylene glycol (PG), butylene glycol (BG), methylpropanediol (MPD), isopentyldiol (IPD), pentylene glycol, 1,2-hexanediol, and hexylene glycol (HG). A comparative analysis was conducted on conventional and non-conventional solvent extractions, focusing on their impact on the bioactive compounds of MAE, encompassing parameters such as total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activities like the 1,1-diphenyl-2-picrylhydrazyl radical scavenging assay (DPPH), the 2,2&#8242;-azino-bis(-3-ethylbenzothiazoline-6-sulphonic acid) radical scavenging assay (ABTS), and the ferric reducing antioxidant power assay (FRAP). The highest values were observed for TPC with aqueous-1,2-hexanediol extraction (52.0 &#177; 3.0 mg GAE/g sample), TFC with aqueous-1,2-hexanediol extraction (20.0 &#177; 1.7 mg QE/g sample), DPPH with aqueous-HG&#160;extraction (13.6 &#177; 0.3 mg TE/g sample), ABTS with aqueous-pentylene glycol extraction (8.2 &#177; 0.1 mg TE/g sample), and FRAP with aqueous-HG extraction (21.1 &#177; 1.3 mg Fe (II) E/g sample). This research aims to advance eco-friendly extraction technology through natural plant components, promoting sustainability by minimizing hazardous chemical use while reducing time and energy consumption, with potential applications in cosmetics.

作者聚焦：使用基于多元醇的微波辅助技术对生物活性化合物进行环保萃取

This protocol details the utilization of a polyol-based microwave-assisted extraction method for extracting phenolic compounds and natural antioxidants, representing a practical and environmentally sustainable approach to the development of ready-to-use extracts.

使用基于多元醇的技术微波辅助萃取用于化妆品应用的酚类化合物和抗氧化剂

The utilization of polyols as green solvents for extracting bioactive compounds from plant materials has gained attention due to their safety and inert ...