Transduction of Endothelial Cells with E6 and E7 Papillomavirus Genes
5:41
Infection of Transduced Endothelial Cells with KSHV
7:38
Results: Phenotypic Changes in KSHV-infected Endothelial Cells
9:15
Conclusion
副本
The overall goal of this procedure is to prepare age-and passage-matched mock in KSHV infected endothelial cells to enable the study of KSHV-associated changes in host cell gene expression including alterations driving malignant transformation in
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Kaposi sarcoma (KS) is a tumor induced by infection with the oncogenic virus human herpesvirus-8/KS herpesvirus (HHV-8/KSHV). The endothelial cell culture model described here is uniquely suited for studying the mechanisms by which KSHV transforms host cells.
