这项工作由中国国家自然科学基金 (81300810 号)、上海市青年医生培训计划 (20141057 号)、上海自然科学基金 (16ZR1405100) 和上海市资助。卫生和计划生育委员会 (201740187 号)。我们感谢 LetPub (www.letpub.com) 在编写本手稿期间提供语言援助。

这一程序涉及人类的主题, 是由中国复旦大学眼科和耳鼻喉科医院的机构审查委员会批准的。所有登记的病人都提供书面知情同意。
1. 手术准备
<ol><li>手术前, 检查病人的鼻腔与前 rhinoscopy, 内窥镜, 和计算机断层扫描 (CT), 以确认和定位的偏差和确定的迹象15。</li>
	<li>让病人评估整个鼻子的通畅性, 并在手术前用视觉模拟量表 (VAS) 表示这一点。 注: 总长度的比例是10厘米, 一个极端是一个完全清晰的鼻子 (即0 厘米评分 0%), 另一种极端完全阻断鼻子 (10 厘米评分 100%), 和中心鼻子与50% 堵塞。</li>
	<li>手术前1天切除两鼻门廊的触须。</li>
	<li>手术当天, 对病人进行全身麻醉后, 将其放置在手术台上16。 注: 诱导麻醉与 2-2.5 毫克/千克丙泊酚, 0.2 µg/公斤 sulfentanyl, 0.6 毫克/千克罗库溴铵。持续静脉输注瑞芬太尼0.1 µg/千克/分, 吸入七氟醚 (0.8 最小肺泡浓度), 保持麻醉。</li>
	<li>将手术台的位置倾斜 (到背高的部位), 将病人的头部置于中性位置 (既不弯曲也不伸展)。</li>
</ol>2. 手术方法
注: 在整个手术过程中使用0度内窥镜。
<ol><li>陡峭的8片纱布 (6 厘米 x 60 厘米), 混合溶液为20毫升1% 丁卡因和4毫升的0.1% 肾上腺素。将1根纱布浸泡在每个鼻腔内5分钟, 收缩鼻腔粘膜。</li>
	<li>在手术结束时, 用电梯将下鼻甲朝向鼻腔侧壁。</li>
	<li>在隔膜两侧的 subperichondrial 和骨膜平面上, 用一根针附着在5毫升注射器上, 用几毫升混合溶液的20毫升0.9% 氯化钠和0.05 毫升0.1% 肾上腺素, 渗入隔膜。 注: 如果隔膜偏离两侧, 我们将凸侧定义为前偏移侧。</li>
	<li>在间隔软骨的最大偏差 (即凸侧) 的一侧, 在黏膜交界处 ipsilaterally 基利安切口, 15 刀片。垂直切口在隔膜上尽可能高, 继续到鼻腔的底部, 当它到达鼻腔的底部时, 曲线向后。 注: 切口需要穿透鼻中隔粘膜软骨膜构建。</li>
	<li>在 subperichondrial 平面上用吸入式升降机在出血时提高粘膜瓣。不流血, 用2毫米或5毫米的电梯抬起皮瓣。将海拔尽可能高的高度伸展至鼻腔底部, 以充分暴露凸侧的软骨和骨隔膜。</li>
	<li>垂直切口使用2毫米升降机的尖端, 或15刀片的软骨, 低于背侧和筛骨的四角软骨和垂直板的交界处 (即, 第一行2LoRs). 同样, 在软骨上进行水平切口, 使其优于四角软骨、犁骨骨和上颌嵴 (即第二行) 的交界处 (图 2A)。 注: 以这种方式, 间隔软骨从其后部和下附着体被动员至骨间隔, 前、上级附着保持完好。</li>
	<li>提高对侧 mucoperiosteum, 以暴露与吸入电梯双边的骨质隔膜。</li>
	<li>切除间隔软骨和相邻骨间隔的后缘和下边缘两条 (图 1B)。<ol>
<li>切除1/4 到 1/3 (偶尔地1/3 到 1/2) 软骨的原始的宽度在前后维度在第一条线 (图 2B)。</li>
		<li>切除1/4 到 1/3 (偶尔地1/3 到 1/2) 软骨的原始的高度在第二条线的垂直维度 (图 2C)。</li>
	</ol>
</li>
	<li>除去增厚的骨间隔偏差, 并进行部分骨折移位, 将偏差移回中线。 注: 广泛切除后和下骨间隔是清除该地区的所有厚度和畸形。</li>
	<li>通过电凝控制术中出血。</li>
	<li>用可吸收材料对两条间断缝合的粘膜瓣进行近似 (图 2D)。<ol>
<li>开始缝合后的切口, 通过他们通过隔膜到相反的一侧, 然后拉他们从皮肤前到切口部位。</li>
		<li>分别缝合缝线。将两条缝合线平行, 一个以上。</li>
	</ol>
</li>
</ol>3. 手术后的程序和评估
<ol><li>用 nasopore 包鼻腔。</li>
	<li>在手术后1周复查患者检查是否有血肿或隔膜感染。</li>
	<li>用前 rhinoscopy 和0度内窥镜检查鼻腔, 并要求患者在手术后6月内用输精管对其鼻通畅进行评估。</li>
	<li>记录术后鼻中隔血肿, 暂时性牙疼, hypesthesia, 粘连, 鼻出血, 鼻中隔脓肿, 鼻中隔摆动, 间隔穿孔, 背部塌陷为手术并发症。</li>
</ol>

<ol>
	<li>Chung, B. J., Batra, P. S., Citardi, M. J., Lanza, D. C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Endoscopic+septoplasty:+revisitation+of+the+technique,+indications,+and+outcomes.">Endoscopic septoplasty: revisitation of the technique, indications, and outcomes.</a> The American Journal of Rhinology. 21 (3), 307-311 (2007).</li><li>Hwang, P. H., McLaughlin, R. B., Lanza, D. C., Kennedy, D. W. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Endoscopic+septoplasty:+indications,+technique,+and+results.">Endoscopic septoplasty: indications, technique, and results.</a> Otolaryngology-Head and Neck Surgery. 120 (5), 678-682 (1999).</li><li>Fettman, N., Sanford, T., Sindwani, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Surgical+management+of+the+deviated+septum:+techniques+in+septoplasty.">Surgical management of the deviated septum: techniques in septoplasty.</a> Otolaryngologic Clinics of North America. 42 (2), 241-252 (2009).</li><li>Killian, G. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+submucous+window+resection+of+the+nasal+septum.">The submucous window resection of the nasal septum.</a> Annals of Otology, Rhinology &amp; Laryngology. 14, 363-393 (1905).</li><li>Freer, O. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+correction+of+deflections+of+the+nasal+septum+with+a+minimum+of+traumatism.">The correction of deflections of the nasal septum with a minimum of traumatism.</a> The Journal of The American Medical Association. 38, 636-642 (1902).</li><li>Aaronson, N. L., Vining, E. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Correction+of+the+deviated+septum:+from+ancient+Egypt+to+the+endoscopic+era.">Correction of the deviated septum: from ancient Egypt to the endoscopic era.</a> International Forum of Allergy &amp; Rhinology. 4 (11), 931-936 (2014).</li><li>Bloom, J. D., Kaplan, S. E., Bleier, B. S., Goldstein, S. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Septoplasty+complications:+avoidance+and+management.">Septoplasty complications: avoidance and management.</a> Otolaryngologic Clinics of North America. 42 (3), 463-481 (2009).</li><li>Rettinger, G., Kirsche, H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Complications+in+septoplasty.">Complications in septoplasty.</a> Facial Plastic Surgery. 22 (4), 289-297 (2006).</li><li>Cottle, M. H., Loring, R. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Newer+concepts+of+septum+surgery;+present+status.">Newer concepts of septum surgery; present status.</a> Eye, Ear, Nose &amp; Throat Monthly. 27 (9), 403-406 (1948).</li><li>Gibson, T., Davis, W. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+distortion+of+autogenous+cartilage+grafts:+Its+causes+and+prevention.">The distortion of autogenous cartilage grafts: Its causes and prevention.</a> British Journal of Plastic Surgery. 10, 257-274 (1958).</li><li>Kenedi, R. M., Gibson, T., Abrahams, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Mechanical+characteristics+of+skin+and+cartilage.">Mechanical characteristics of skin and cartilage.</a> Human Factors. 5, 525-529 (1963).</li><li>Stenstroem, S. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+&amp;#34;natural&amp;#34;+technique+for+correction+of+congenitally+prominent+ears.">A &amp;#34;natural&amp;#34; technique for correction of congenitally prominent ears.</a> Plastic and Reconstructive Surgery. 32, 509-518 (1963).</li><li>Fry, H. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Interlocked+stresses+in+human+nasal+septal+cartilage.">Interlocked stresses in human nasal septal cartilage.</a> British Journal of Plastic Surgery. 19 (3), 276-278 (1966).</li><li>Wang, T., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+modified+septoplasty+with+three+high+tension+lines+resection.">A modified septoplasty with three high tension lines resection.</a> Acta Oto-Laryngologica. 130 (5), 593-599 (2010).</li><li>Trimarchi, M., Bellini, C., Toma, S., Bussi, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Back-and-forth+endoscopic+septoplasty:+analysis+of+the+technique+and+outcomes.">Back-and-forth endoscopic septoplasty: analysis of the technique and outcomes.</a> International Forum of Allergy &amp; Rhinology. 2 (1), 40-44 (2012).</li><li>Kilicaslan, A., Acar, G. O., Tekin, M., Ozdamar, O. I. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Assessment+the+long-term+effects+of+septoplasty+surgery+on+olfactory+function.">Assessment the long-term effects of septoplasty surgery on olfactory function.</a> Acta Oto-Laryngologica. 136 (10), 1079-1084 (2016).</li><li>Meeuwis, J., Verwoerd-Verhoef, H. L., Verwoerd, C. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Normal+and+abnormal+nasal+growth+after+partial+submucous+resection+of+the+cartilaginous+septum.">Normal and abnormal nasal growth after partial submucous resection of the cartilaginous septum.</a> Acta Oto-Laryngologica. 113 (3), 379-382 (1993).</li><li>Lopatin, A. S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Do+laws+of+biomechanics+work+in+reconstruction+of+the+cartilaginous+nasal+septum.">Do laws of biomechanics work in reconstruction of the cartilaginous nasal septum.</a> European Archives of Oto-Rhino-Laryngology. 253 (4-5), 309-312 (1996).</li><li>D'Ascanio, L., Manzini, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Quick+septoplasty:+surgical+technique+and+learning+curve.">Quick septoplasty: surgical technique and learning curve.</a> Aesthetic Plastic Surgery. 33 (6), 814-818 (2009).</li></ol>

作者没有什么可透露的。

2LoRs 程序是基于胚胎和解剖知识的歪鼻隔膜。鼻中隔由三种不同成分组成: 前膜、中间软骨、后骨和下骨骼。在鼻中隔发育过程中, 不同的组分僵化不同的时间序列。通常认为, 当软骨仍在生长时, 骨骼就能完成伸展。因此, 应力堆积在相邻的骨间隔软骨的边缘, 导致最初的力量, 可能会变形的鼻中隔。因此, 在大多数情况下, 鼻中隔偏离一定程度从中线位置14。因此, 2LoRs 的原则是改...

内镜鼻中隔成形术是耳鼻咽喉部常见的手术方法, 用于治疗鼻中隔偏1引起的鼻气道梗阻。鼻中隔成形术鼻气道梗阻的目的是为鼻气道通畅提供功能性改善, 其原则是矫正间隔偏差, 以最小的手术侵袭率2。
鼻中隔成形术的起点, 今天仍然使用的做法, 追溯到自由和基利安出版的技术在第二十世纪初, 叫黏膜下切除 (SMR)3。SMR 的特点是它直接去除了 subperichondrial 平面上的鼻软骨的偏差, 留下一个 L 形的支撑结构支持鼻子4,5的外观。SMR 在当时的技术上表现出优势, 因此逐渐得到了认可。二十世纪九十年代, 内窥镜应用于鼻中隔成形术1。手术现场的光照和可视化程度均有明显提高, 切除术可直接、准确地进行6。在此之后, 对 SMR 的适应症进行了扩展, 并开发了各种鼻中隔成形术技术。虽然这些技术可以在切口、皮瓣抬高、切除、缝合或包装等方面多样化, 但直接去除的本质并没有改变。因此, 一旦软骨明显切除, 并发症如大间隔穿孔或鞍鼻畸形将发生7,8。
正如卡托和洛林在1948年提出的, 偏软骨切除术应保守9。不同于直接去除软骨的偏差, 软骨的生物力学应用于鼻中隔成形术需要利用软骨的固有弹性特性, 以矫正软骨的偏差由有限的手术干预, 如部分切口 (如划伤或薄片) 和全切口 (例如, 全切或楔形)。在 1958年, 吉布森和戴维斯首次报道, 由于其生长模式10, 软骨有一个内部的自锁应力系统。部分切口在凹边将释放重音, 从而减少软骨的鞠躬, 而凸边切口将增加鞠躬。在 1963年, Kenedi, 吉布森和亚伯拉罕进一步展示了自锁应力系统通过一系列的研究绘制的力量分布在肋骨软骨截面11。同年, 史丹斯壮验证了部分切口对 antihelix12的影响。几年后, 南联盟公布的结果, 在人鼻中隔软骨, 是一致的13。换句话说, 软骨的生物力学可以通过释放软骨中的力量来改变软骨的形态。在此基础上, 提出了利用软骨生物力学特征的外科手术方法14。
结合以前的手术程序与鼻中隔的胚胎和解剖学知识, 在这里, 一个改良内镜鼻中隔成形术程序与技术的有限两线切除 (2LoRs) 在后和下连接软骨和骨间隔 (图 1) 详细介绍。本程序建议在外部鼻畸形缺席时矫正鼻中隔偏鼻, 改善鼻腔通畅, 或改善进入中鼻道或中部鼻甲腋区作为术前手术的途径。这一程序也可以用于儿童纠正间隔偏差, 因为它的微创方法。

<table><tbody><tr><td>Nasal Endoscopy (0&lt;sup&gt;o&lt;/sup&gt;)</td><td>Karl Storz-Endoskope</td><td>7230 AA</td><td></td></tr><tr><td>Tetracaine</td><td>Eye &amp;amp; ENT Hospital of Fudan University</td><td>180130</td><td></td></tr><tr><td>Epinephrine Hydrochloride Injection</td><td>Shanghai Harvest Pharmaceutical Co., Ltd</td><td>10170405</td><td></td></tr><tr><td>Number 15 blade</td><td>Shanghai Pudong Jinhuan Medical Products Co., Ltd</td><td>35T1205</td><td></td></tr><tr><td>Suction Elevator</td><td>Zhejiang Tian Song Medical Products Co., Ltd</td><td>B2117.1</td><td>Width: 4 mm</td></tr><tr><td>Electrocoagulation</td><td>Shanghai Hutong Electronics. Co.,Ltd</td><td>GD350-B5</td><td></td></tr><tr><td>4-0 Brided Absorbable Suture</td><td>Covidien Healthcare</td><td>SL-691</td><td></td></tr><tr><td>Rongeur forcep</td><td>Zhejiang Tian Song Medical Products Co., Ltd</td><td>B2300.3</td><td></td></tr><tr><td>Nasopore</td><td>Nasopore, Stryker, USA</td><td></td><td>Lengh: 8 cm</td></tr><tr><td>Gauze</td><td>Ningbo Shenyuan Medical Material Co., Ltd</td><td></td><td>6 cm x 60 cm</td></tr><tr><td>5mm Elevator</td><td>Zhejiang Tian Song Medical Products Co., Ltd</td><td>B2067</td><td>Width: 5 mm</td></tr><tr><td>2mm Elevator</td><td>Shanghai Medical Instruments (Group) Ltd., Corp. Surgical Instruments Factory</td><td>HBL020</td><td>Width: 2 mm</td></tr></tbody></table>

endoscopic septoplasty with limited two-line resection: minimally invasive surgery for septal deviation

内镜鼻中隔成形术是耳鼻喉科的一种外科手术, 通常用于治疗鼻中隔偏压引起的鼻气道梗阻。它的历史悠久, 有多种变体。本文以胚胎和解剖知识为基础, 采用有限的双线切除 (2LoRs) 技术, 在软骨和骨间隔的后、下交界处进行了改良的内镜鼻中隔成形术手术。鼻中隔和软骨行为的生物力学。采用此方法可以尽可能地保留四边形软骨, 有利于保留隔膜的支撑框架和刚度。2LoRs. 经证实, 鼻间隔偏差的矫正与少见的并发症是有效和合理的。本修改后的程序可适用于矫正鼻中隔不存在任何外部鼻畸形, 以改善鼻腔通畅或改善进入中道或腋窝地区的中鼻甲。它也可能被用来扩大鼻中隔成形术的迹象, 因为它的微创方法的儿童和青少年。

本研究包括成人患者 (> 18 岁) 鼻中隔偏差。鼻间隔偏差患者伴有慢性鼻窦炎、鼻肿瘤、外鼻畸形以及以前鼻中隔成形术手术史的病人除外。患者的直背部, 但谁有骶部软骨脱臼的大鼻翼, 已突出成一个鼻门廊也排除了。
本研究包括三十二例患者。患者的平均年龄为44.7 岁 (19-72 岁), 68% 为男性, 32% 为女性。输精管评分显示为平均?...

Watch this Scientific Journal Video about Endoscopic Septoplasty with Limited Two-line Resection: Minimally Invasive Surgery for Septal Deviation at JoVE.com

Endoscopic Septoplasty with Limited Two-line Resection: Minimally Invasive Surgery for Septal Deviation

内镜鼻中隔成形术是一种具有多种变异的具有悠久历史的外科手术方法。本文的重点是一步一步的手术方法执行一项改良的鼻中隔成形术程序称为有限的两线切除术。这种手术技术可用于矫正鼻中隔偏歪, 在没有外部鼻畸形。

内镜下鼻中隔成形术有限双线切除: 间隔偏差微创手术

Endoscopic septoplasty is a surgical procedure in otolaryngology that is commonly performed to treat nasal airway obstruction caused by nasal septal ...

endoscopic-septoplasty-with-limited-two-line-resection-minimally

Research

Education

JoVE Core

JoVE Journal

Anatomy and Physiology

Medicine

Unit 1

The Axial Skeleton

SCIENTISTS IN ACTION

16.5K 次观看.  Fudan University. 内镜鼻中隔成形术是一种具有多种变异的具有悠久历史的外科手术方法。本文的重点是一步一步的手术方法执行一项改良的鼻中隔成形术程序称为有限的两线切除术。这种手术技术可用于矫正鼻中隔偏歪, 在没有外部鼻畸形。

视频: Endoscopic Septoplasty with Limited Two-line Resection: Minimally Invasive Surgery for Septal Deviation

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function

We describe a novel esophagogastric anastomotic technique (&ldquo;side-to-side: staple line-on-staple line&rdquo;, STS) for intrathoracic anastomoses designed to create a large diameter anastomosis while simultaneously maintaining conduit blood supply. This technique aims to minimize the incidence of anastomotic leaks and strictures, which is a frequent source of morbidity and occasional mortality after esophagectomy. We analyze the results of this STS technique on 368 patients and compared outcomes to 112 patients who underwent esophagogastric anastomoses using an end-to-end stapler (EEA) over an 8-year time interval at our institution.
The STS technique involves aligning the remaining intrathoracic esophagus over the tip of the lesser curve staple line of a stomach tube, created as a replacement conduit for the esophagus. A linear stapling device cuts through and restaples the conduit staple line to the lateral wall of the esophagus in a side-to-side fashion. The open common lumen is then closed in two layers of sutures.
There was a total of 12 (3.8%) anastomotic leaks in patients who underwent STS esophagogastric anastomosis. Two of eight patients (25%) had anastomotic leaks after esophagectomy for end-stage achalasia as compared to a 2.8% leak rate (10/336) after esophagectomy for other conditions. Eighteen (5.2%) patients required a median of 2 dilatations for anastomotic stricture after STS anastomosis. Supplemental jejunostomy feedings were required in only 11.1% of patients undergoing STS anastomoses following hospital discharge. In contrast, patients undergoing EEA anastomoses demonstrated anastomotic leak and stricture rates of 16.1% and 14.3% respectively (p&lt;0.01). Time analysis of postoperative contrast studies following the STS technique typically demonstrated a straight/uniform diameter conduit with essentially complete contrast emptying into the small bowel within 3 minutes in 88.4% of patients.
The incidence of esophagogastric anastomotic leaks and strictures were extremely low using this novel anastomotic technique. Additionally we believe that based on time and qualitative analyses of postoperative contrast studies, this technique appears to optimize postoperative upper gastrointestinal tract function; however, further comparative studies are needed.

We describe a novel intrathoracic esophagogastric anastomotic technique designed to create a large diameter anastomosis while simultaneously maintaining conduit blood supply to minimize the incidence of anastomotic leaks and strictures. Construction and orientation of the stomach conduit designed to optimize upper gastrointestinal tract function is also described.

静脉造影切除术，旨在最大限度地减少麻醉并发症和优化导管功能

We describe a novel esophagogastric anastomotic technique (&ldquo;side-to-side: staple line-on-staple line&rdquo;, STS) for intrathoracic anastomoses ...

科研

癌症研究

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Endoscopic endonasal trans-sphenoidal surgery has become the gold standard for the surgical treatment of pituitary adenomas and many other pituitary lesions. Refinements in surgical techniques, technological advancements, and incorporation of neuronavigation have rendered this surgery minimally invasive. The complication rates of this surgery are very low while excellent results are consistently obtained through this approach.
This paper focuses on the step-by-step surgical approach to pituitary adenomas, which is based on personal experience, and details the results obtained with this minimally invasive surgery.

The aim of this paper is to describe the different steps of the endoscopic endonasal approach to the sella turcica.

内镜下鼻跨蝶入路: 垂体腺瘤的微创手术

Endoscopic endonasal trans-sphenoidal surgery has become the gold standard for the surgical treatment of pituitary adenomas and many other pituitary ...

神经科学

Transcanalicular Diode Laser-assisted Dacryocystorhinostomy for the Treatment of Primary Acquired Nasolacrimal Duct Obstruction

Today&#39;s gold standard in the treatment of infrasaccal primary acquired nasolacrimal duct obstruction (PANDO) is external dacryocystorhinostomy (DCR), a relatively invasive procedure that can be performed after failure of recanalizing treatments. However, with progress in the field of diode laser technology, new approaches have emerged. Laser-assisted transcanalicular DCR with subsequent bicanalicular silicon intubation is a new option showing great promise as a viable minimally invasive procedure. Under permanent endoscopic visual control from the nasal cavity, a diode laser fiber is inserted into the lacrimal sac and laser energy is applied to create a bony ostium between the lacrimal sac and the nasal cavity. Since no skin incision needs to be made, advantages of this method comprise the sparing of the skin as well as the medial palpebral structures and the physiological palpebral-canalicular pump mechanism. The duration of surgery as well as reconvalescence is generally shorter than with external DCR. Complications include silicon tube prolapse, mild swelling and, rarely, canalicular infection and thermal injury. One-year functional success rates, defined as complete resolution of symptoms and ostium patency, are high, yet still range behind those of external DCR. However, secondary external DCR after failure of laser-assisted DCR can be performed without difficulty. Thus, laser-assisted transcanalicular DCR is a valid option that should be considered as a second-step procedure after failure of recanalization procedures and before external DCR.

The goal of this protocol is to present transcanalicular laser-assisted dacryocystorhinostomy as a minimally invasive approach in the treatment of primary acquired nasolacrimal duct obstruction.

Transcanalicular 二极管激光辅助泪囊鼻腔吻合术治疗原发性鼻泪管阻塞

Today&#39;s gold standard in the treatment of infrasaccal primary acquired nasolacrimal duct obstruction (PANDO) is external dacryocystorhinostomy (DCR), ...

医学

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Despite the obvious advantages of the preservation of a normal aortic valve during aortic root replacement, the complexity of valve sparing procedures prevents a number of cardiac surgeons from incorporating them into their practice. The aim of this protocol is to describe a simplified and user-friendly technique of an aortic valve-sparing root replacement (VSRR) procedure by re-implantation of the aortic valve. Proper selection of patients and limitations of the technique are discussed.
In 54 consecutive patients, normal appearing aortic valves were re-implanted in a commercially available polyester prosthesis with pre-shaped sinuses by a simplified and standardized technique. Placement of the first row of the proximal suture line, choice of the prosthesis size, and adjustment of the height of the commissures of the patient to the fixed height of the sinus portion of the prosthesis were slightly modified from the reference techniques with the aim of increasing its feasibility for use by other cardiac surgeons. Early mortality and morbidity as well as 5-year survival, freedom from aortic valve reoperation, and freedom from recurrent moderate regurgitation were collected in all patients.
Thirty-day mortality, re-sternotomy for bleeding, re-sternotomy for mediastinitis, and the incidence of stroke were very low, 1.8% for each (1 of 54). No patient required permanent pace-maker implantation. At 5 years, survival, freedom from aortic valve reoperation, and freedom from recurrent moderate regurgitation were 97.5%, 95.2%, and 91.6%, respectively.
Mid-term results of our standardized technique of re-implantation of the aortic valve for valve-sparing aortic root replacement are very good and compare with more complex techniques reported by experienced surgeons. By following the present protocol of the standardized re-implantation technique, a greater number of cardiac surgeons can perform this procedure with comparable good results.

Valve-sparing aortic root replacement has the advantage of preserving the patient&#39;s own aortic valve. The complexity of the reported techniques to date restricts their use to a limited number of cardiac surgeons. This protocol describes step-by-step a standardized technique reproducible by a greater number of cardiac surgeons.

主动脉瓣重置术治疗瓣膜备用主动脉根置换的规范化技术

Despite the obvious advantages of the preservation of a normal aortic valve during aortic root replacement, the complexity of valve sparing procedures ...

Combined Endoscopic and Transoral Approach for Total Maxillectomy

The technique of maxillectomy has been revised since it was first described in the 1820s. During the past decade, the endoscopic approach has been widely practiced for resecting maxilla. Compared with the traditional approaches, the combined endoscopic and transoral approach has many advantages such as avoiding facial incisions and postoperative scars and better visualization of the surgical margin. However, this technique is complicated to master and possess several challenges. Here, we demonstrate this approach step-by-step to show how to perform a total maxillectomy. We also reported nine cases with malignant tumors originating from the maxilla, and for all of them total maxillectomy was performed with combined endoscopic and transoral approach. Our data showed that the combination of the endoscopic and transoral approach could be used to resect the total maxilla successfully, though the tumor extended to the infratemporal and pterygopalatine fossa should be treated very carefully to avoid its spread in the local area. Furthermore, besides denture, other reconstruction methods should be attempted to improve the postoperative quality of life after the total maxillectomy.

The technique of maxillectomy has been revised since it was first described in the 1820s. During the past decade, the endoscopic approach has been widely ...

Low-Cost Single-Port (LoCoSP) Device for a Transcervical Approach in Minimally Invasive Transhiatal Esophagectomy

Esophagectomy remains the preferred option to achieve curative treatment in advanced esophageal cancer, but the choice of surgical approach remains controversial. A transthoracic approach may improve lymph node dissection, but it has considerable morbidity and respiratory complications. Transhiatal access has been demonstrated as an efficient means of minimizing post-operative complications. Minimally invasive transhiatal esophagectomy may reduce operative trauma and morbidity as well as enhance postoperative recovery with no compromise in cancer recurrence or survival. Nevertheless, it has a technical limitation in terms of cervical esophagus dissection. Thus, a low-cost single-port device was developed to complete upper mediastinal dissection by a transcervical approach during minimally invasive transhiatal esophagectomy. This device uses a nasogastric tube, a number-eight sterile glove, a sterile sponge, and 3 permanent 5-mm trocars. The step-by-step process of transhiatal esophagectomy and the development of this device are described. This technique allows for the dissection of the upper mediastinum, as well as the esophagus over the aortic arch and behind the superior portion of the trachea. The harvesting of lymph nodes along the left recurrent laryngeal nerve and paratracheals was improved.

Low-Cost Single-Port LoCoSP Device for a Transcervical Approach in Minimally Invasive Transhiatal Esophagectomy

Here, we describe a step-by-step description of transhiatal esophagectomy and the development of a low-cost single-port device for a transcervical approach in a minimally invasive transhiatal esophagectomy.

低成本单端口 （LoCoSP） 设备，用于微创性跨侵入性食管切除术中的内脏方法

Esophagectomy remains the preferred option to achieve curative treatment in advanced esophageal cancer, but the choice of surgical approach remains ...

Endoscopic Cholesteatoma Surgery

Implementation of endoscopes in cholesteatoma surgery resulted in considerable changes in the management of cholesteatoma in the last two decades. Compared to the microscopic approach with an excellent but straight-line view and limited illumination, the introduction of endoscopes provides a wide-angled panoramic view. Moreover, angled lenses allow the surgeon to visualize the middle ear and its hidden recesses through a transcanal, minimally-invasive approach. The endoscope enables the surgeon to remove limited cholesteatoma of the middle ear and its recesses using an exclusive endoscopic technique by taking advantage of these benefits. This reduces the rate of residual disease and sparing external incisions and excessive temporal bone drilling as in a transmastoid approach. Since transcanal endoscopic access is mainly a one-handed technique, it implies the need for specific procedures and technical refinements. This article describes a step-by-step guide as a surgical manual for endoscopic removal of epitympanic cholesteatoma. Different techniques for cholesteatoma dissection and bone removal for epitympanectomy, including curettage and powered instruments such as drills and ultrasonic devices with their outcomes, are discussed. This may offer ear surgeons insight into technical refinements and the latest technological developments and open the horizon for different techniques.

The present protocol describes a step-by-step guide for the complete endoscopic removal of epitympanic cholesteatoma with different techniques for cholesteatoma dissection and bone removal for epitympanectomy.

内窥镜胆脂瘤手术

Implementation of endoscopes in cholesteatoma surgery resulted in considerable changes in the management of cholesteatoma in the last two decades. ...

Full-Endoscopic Interlaminar Approach for Decompression of Lateral Recess Stenosis

For lateral recess stenosis, extensive decompression with laminectomy is still performed in most centers. However, tissue-sparing surgeries are becoming more common. Full-endoscopic spinal surgeries have the advantages of being less invasive and offering a shorter recovery time. Here, we describe the technique of the full-endoscopic interlaminar approach for the decompression of lateral recess stenosis. The full-endoscopic interlaminar approach for the lateral recess stenosis procedure took approximately 51 min (range of 39-66 min). Blood loss could not be measured due to continuous irrigation. However, no drainage was required. There were no dura mater injuries reported in our institution. Furthermore, there were no injuries to the nerves, no cauda equine syndrome, and no hematoma formation. The patients were mobilized on the same day as surgery and discharged the next day. Therefore, the full-endoscopic technique for lateral recess stenosis decompression is a feasible procedure that lowers the operational time, complications, traumatization, and rehabilitation duration.

Technical advances and increased experience in full-endoscopic spinal surgeries enable these procedures to be performed with minimal incision, muscle retraction, and bone removal.

For lateral recess stenosis, extensive decompression with laminectomy is still performed in most centers. However, tissue-sparing surgeries are becoming ...

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Reduced-port laparoscopic surgery (RPLS) has been widely used for the radical resection of gastrointestinal tumors. Single-surgeon, three-port, laparoscopic radical resection for sigmoid colon or high rectal cancer with natural orifice specimen extraction surgery (NOSES) has the advantage of a small incision, quick postoperative recovery, and short hospital stay. Yet, there are still only a few reports on NOSES. This paper describes the indications, preoperative preparations, surgical steps, and precautions for single-surgeon, three-port, laparoscopic radical resection of the sigmoid colon and high rectal cancer, and intraoperative specimen collection through the natural orifice. 
The protocol focuses on the steps of radical dissection and the main technical points of resection and reconstruction. At the same time, a procedure for fixing an anvil seat by self-traction of extracorporeal silk thread, used for purse-string suture fixation after the proximal anvil was placed in the abdominal cavity, was creatively improved. This operation could effectively avoid problems such as an insufficient proximal intestinal tube, shaking off the anvil seat, and weak purse-string suture during a single operation. The surgical care had less variability and was easy to perform, effectively avoiding postoperative anastomotic leakage and bleeding due to excessive intraoperative anastomotic tissue. This surgery could be widely promoted in primary hospitals.

Here, we present a protocol to successfully perform single-surgeon, three-port, laparoscopic resection for colorectal cancer with natural orifice specimen extraction.

单外科医生、三孔腹腔镜切除术自然孔口标本提取治疗结直肠癌的临床应用

Reduced-port laparoscopic surgery (RPLS) has been widely used for the radical resection of gastrointestinal tumors. Single-surgeon, three-port, ...

<meta charset="utf8"></head><body>独家内窥镜听球成形术的综合分步指南

Techniques of Endoscopic Ossiculoplasty

The utilization of endoscopes in modern otology has evolved from diagnostic purposes to the development of exclusive endoscopic ear surgery. This technique offers a panoramic view of the middle ear and provides an optimal magnification of the oval window region, the stapes' suprastructure, and the footplate, allowing great precision in prosthesis positioning during ossiculoplasty (OPL). Various techniques for ossicular chain reconstruction have been described in the literature. Either autologous or synthetic materials can be used for reconstruction. The use of a patient's own tissue minimizes the risk of implant rejection or extrusion of the prosthesis through the tympanic membrane. On the other hand, synthetic materials like titanium are light and rigid and do not require time-consuming prosthesis remodeling. The main objective of this article is to present a comprehensive step-by-step guide that serves as a surgical manual for exclusive endoscopic OPL. This guide will explain various forms of OPL using synthetic and autologous materials. The goal is to provide a comprehensive understanding of the various surgical techniques and support the integration into clinical practice.

<meta charset="utf8"></head><body>作者聚焦:推进内窥镜听球成形术 – 临床整合的技术、创新和实践指导

Exclusive Endoscopic ossiculoplasty (EEO) is a promising and minimally invasive approach for the treatment of conductive hearing loss due to ossicular chain disruptions and associated middle ear pathologies. Herein, step-by-step instructions and a discussion of various endoscopic ossiculoplasty techniques are presented.

内镜下鼻中隔成形术有限双线切除: 间隔偏差微创手术

摘要

探索更多视频

此视频中的章节

静脉造影切除术，旨在最大限度地减少麻醉并发症和优化导管功能

内镜下鼻跨蝶入路: 垂体腺瘤的微创手术

Transcanalicular 二极管激光辅助泪囊鼻腔吻合术治疗原发性鼻泪管阻塞

主动脉瓣重置术治疗瓣膜备用主动脉根置换的规范化技术

Combined Endoscopic and Transoral Approach for Total Maxillectomy

低成本单端口（LoCoSP）设备，用于微创性跨侵入性食管切除术中的内脏方法

内窥镜胆脂瘤手术

Full-Endoscopic Interlaminar Approach for Decompression of Lateral Recess Stenosis

单外科医生、三孔腹腔镜切除术自然孔口标本提取治疗结直肠癌的临床应用

内窥镜听骨成形术的技术

内镜下鼻中隔成形术有限双线切除: 间隔偏差微创手术

摘要

探索更多视频

此视频中的章节

静脉造影切除术，旨在最大限度地减少麻醉并发症和优化导管功能

内镜下鼻跨蝶入路: 垂体腺瘤的微创手术

Transcanalicular 二极管激光辅助泪囊鼻腔吻合术治疗原发性鼻泪管阻塞

主动脉瓣重置术治疗瓣膜备用主动脉根置换的规范化技术

Combined Endoscopic and Transoral Approach for Total Maxillectomy

低成本单端口 （LoCoSP） 设备，用于微创性跨侵入性食管切除术中的内脏方法

内窥镜胆脂瘤手术

Full-Endoscopic Interlaminar Approach for Decompression of Lateral Recess Stenosis

单外科医生、三孔腹腔镜切除术自然孔口标本提取治疗结直肠癌的临床应用

内窥镜听骨成形术的技术

低成本单端口（LoCoSP）设备，用于微创性跨侵入性食管切除术中的内脏方法