Results: Localized Effects of Blood Flow Manipulation in Near-Term and Preterm Fetus and Sheep
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Conclusion
副本
Previously, the chief method to examine the effect of chemicals on arterial contractility was by ex vivo wire myography in organ baths. The significance of this technique is that the effects of chemicals and gene manipulation on a vessel's segment
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The present protocol describes a method to deliver drugs and gene expression-modifying agents perivascularly in an in utero developing fetus. Importantly, the effect of drugs/agents on blood flow can be measured with the progression of pregnancy.
