Robert H. Edwards

Glutamine uptake by neurons: interaction of protons with system a transporters.

Regulation of the glutamine transporter SN1 by extracellular pH and intracellular sodium ions.

The glutamine commute: take the N line and transfer to the A.

Cell-specific expression of the glutamine transporter SN1 suggests differences in dependence on the glutamine cycle.

Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis.

The identification of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamate.

Vesicular neurotransmitter transporter expression in developing postnatal rodent retina: GABA and glycine precede glutamate.

Postnatal development of the glutamate vesicular transporter VGLUT1 in rat cerebral cortex.

The H+-coupled electrogenic lysosomal amino acid transporter LYAAT1 localizes to the axon and plasma membrane of hippocampal neurons.

Organic anion transport is the primary function of the SLC17/type I phosphate transporter family.

Cellular localization of three vesicular glutamate transporter mRNAs and proteins in rat spinal cord and dorsal root ganglia.

Complementary distribution of vesicular glutamate transporters 1 and 2 in the nucleus accumbens of rat: Relationship to calretinin-containing extrinsic innervation and calbindin-immunoreactive neurons.

Plasma membrane and vesicular glutamate transporter mRNAs/proteins in hypothalamic neurons that regulate body weight.

Expression of plasma membrane GABA transporters but not of the vesicular GABA transporter in dentate granule cells after kainic acid seizures.

Complementary distribution of type 1 cannabinoid receptors and vesicular glutamate transporter 3 in basal forebrain suggests input-specific retrograde signalling by cholinergic neurons.

Electrochemical monitoring of transport by a vesicular monoamine transporter expressed in Xenopus oocytes.

VGLUTs define subsets of excitatory neurons and suggest novel roles for glutamate.

Vesicular glutamate transporters 1 and 2 target to functionally distinct synaptic release sites.

Endocannabinoid-independent retrograde signaling at inhibitory synapses in layer 2/3 of neocortex: involvement of vesicular glutamate transporter 3.

Lipid rafts mediate the synaptic localization of alpha-synuclein.

Vesicular glutamate transporter 3 expression identifies glutamatergic amacrine cells in the rodent retina.

Evidence that certain retinal bipolar cells use both glutamate and GABA.

The effect of rare human sequence variants on the function of vesicular monoamine transporter 2.

Normal biogenesis and cycling of empty synaptic vesicles in dopamine neurons of vesicular monoamine transporter 2 knockout mice.

Expression of the vesicular glutamate transporters during development indicates the widespread corelease of multiple neurotransmitters.

Antidepressants and the monoamine masquerade.

A combinatorial code for the interaction of alpha-synuclein with membranes.

Sorting of vesicular monoamine transporter 2 to the regulated secretory pathway confers the somatodendritic exocytosis of monoamines.

Neural activity controls the synaptic accumulation of alpha-synuclein.

Functional implications of neurotransmitter co-release: glutamate and GABA share the load.

Changes in purinergic signaling after cerebral injury -- involvement of glutamatergic mechanisms?

Structural variants in the vesicular monoamine transporter do not contribute to sporadic Parkinson's disease.

PharmGKB submission update: VI. PMT submissions of genetic variations in neurotransmitter transporters (SLC6, SLC17, and SLC18) to the PharmGKB network.

Vesicular glutamate transporter 3 (VGLUT3) identifies spatially segregated excitatory terminals in the rat substantia nigra.

Distribution of vesicular glutamate transporters 1 and 2 in the rat spinal cord, with a note on the spinocervical tract.

Distinct endocytic pathways control the rate and extent of synaptic vesicle protein recycling.

Synaptic vesicles: half full or half empty?

Alpha-synuclein overexpression increases cytosolic catecholamine concentration.

Secretion of L-glutamate from osteoclasts through transcytosis.

Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis.

Do different endocytic pathways make different synaptic vesicles?

Thyronamines inhibit plasma membrane and vesicular monoamine transport.

Vesicular glutamate transporter 1 is required for photoreceptor synaptic signaling but not for intrinsic visual functions.

Physiology versus pathology in Parkinson's disease.

The neurotransmitter cycle and quantal size.

Vesicular neurotransmitter transporters as targets for endogenous and exogenous toxic substances.

Pharmacology of neurotransmitter transport into secretory vesicles.

Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3.

Expression and function of the rat vesicular monoamine transporter 2.

Vesicular glutamate and GABA transporters sort to distinct sets of vesicles in a population of presynaptic terminals.

Vesicular glutamate transporter 3-immunoreactive pericellular baskets ensheath a distinct population of neurons in the lateral septum.

Fast subplasma membrane Ca2+ transients control exo-endocytosis of synaptic-like microvesicles in astrocytes.

Optical reporters for the conformation of alpha-synuclein reveal a specific interaction with mitochondria.

Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons.

Synaptic and extrasynaptic factors governing glutamatergic retinal waves.

Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals.

Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors.

Glutamate co-release at GABA/glycinergic synapses is crucial for the refinement of an inhibitory map.

Localized topological changes of the plasma membrane upon exocytosis visualized by polarized TIRFM.

Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis.

The behavior of alpha-synuclein in neurons.

Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo.

Vesicular monoamine and glutamate transporters select distinct synaptic vesicle recycling pathways.

Dopaminergic terminals in the nucleus accumbens but not the dorsal striatum corelease glutamate.

Metabolic control of vesicular glutamate transport and release.

VGLUT2 expression in primary afferent neurons is essential for normal acute pain and injury-induced heat hypersensitivity.

RNAi screen identifies a role for adaptor protein AP-3 in sorting to the regulated secretory pathway.

Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein.

Cholinergic interneurons mediate fast VGluT3-dependent glutamatergic transmission in the striatum.

Pathway-specific genetic attenuation of glutamate release alters select features of competition-based visual circuit refinement.

Expression of vesicular glutamate transporters type 1 and 2 in sensory and autonomic neurons innervating the mouse colorectum.

v-SNARE composition distinguishes synaptic vesicle pools.

Genetic targeting and physiological features of VGLUT3+ amacrine cells.

Presynaptic regulation of quantal size: K+/H+ exchange stimulates vesicular glutamate transport.

Neurotransmitter corelease: mechanism and physiological role.

Vesicular and plasma membrane transporters for neurotransmitters.

Dopamine dysregulation in a mouse model of paroxysmal nonkinesigenic dyskinesia.