Benjamin D. Hedley

Therapeutic targets for antimetastatic therapy.

Tumor dormancy and the role of metastasis suppressor genes in regulating ectopic growth.

The thrombin inhibitor Argatroban reduces breast cancer malignancy and metastasis via osteopontin-dependent and osteopontin-independent mechanisms.

Downregulation of osteopontin contributes to metastasis suppression by breast cancer metastasis suppressor 1.

BRMS1 suppresses breast cancer metastasis in multiple experimental models of metastasis by reducing solitary cell survival and inhibiting growth initiation.

High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability.

Tumor dormancy and metastasis.

The synthetic triterpenoid CDDO-Imidazolide suppresses experimental liver metastasis.

The role of erythropoietin and erythropoiesis-stimulating agents in tumor progression.

Recombinant human erythropoietin in combination with chemotherapy increases breast cancer metastasis in preclinical mouse models.

User-defined protein marker assay development for characterization of circulating tumor cells using the CellSearch® system.

Response to Rossi et al.

Determination of optimal replicate number for validation of imprecision using fluorescence cell based assays: Proposed practical method.

Determination of optimal replicate number for validation of imprecision using fluorescence cell-based assays: Proposed practical method.