London Regional Cancer Program
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Triple-Negative Primary Breast Tumors Induce Supportive Premetastatic Changes in the Extracellular Matrix and Soluble Components of the Lung Microenvironment.
Cancers Jan, 2020 | Pubmed ID: 31936750
Detection and quantification of circulating tumor cells in mouse models of human breast cancer using immunomagnetic enrichment and multiparameter flow cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology May, 2005 | Pubmed ID: 15810015
A new model for lymphatic metastasis: development of a variant of the MDA-MB-468 human breast cancer cell line that aggressively metastasizes to lymph nodes.
Clinical & experimental metastasis , 2005 | Pubmed ID: 16170671
Role of the integrin-binding protein osteopontin in lymphatic metastasis of breast cancer.
The American journal of pathology Jul, 2006 | Pubmed ID: 16816376
Tumor dormancy and the role of metastasis suppressor genes in regulating ectopic growth.
Future oncology (London, England) Oct, 2006 | Pubmed ID: 17026454
Tumor dormancy and cancer stem cells: implications for the biology and treatment of breast cancer metastasis.
Breast disease , 2006-2007 | Pubmed ID: 17473368
Osteopontin overexpression in breast cancer: knowledge gained and possible implications for clinical management.
Journal of cellular biochemistry Nov, 2007 | Pubmed ID: 17721886
The thrombin inhibitor Argatroban reduces breast cancer malignancy and metastasis via osteopontin-dependent and osteopontin-independent mechanisms.
Breast cancer research and treatment Nov, 2008 | Pubmed ID: 18097747
Downregulation of osteopontin contributes to metastasis suppression by breast cancer metastasis suppressor 1.
International journal of cancer. Journal international du cancer Aug, 2008 | Pubmed ID: 18470911
High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability.
Journal of cellular and molecular medicine Aug, 2009 | Pubmed ID: 18681906
Characterization of tumor cell dissemination patterns in preclinical models of cancer metastasis using flow cytometry and laser scanning cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology Apr, 2009 | Pubmed ID: 18855920
Lymphatic metastasis of breast cancer cells is associated with differential gene expression profiles that predict cancer stem cell-like properties and the ability to survive, establish and grow in a foreign environment.
International journal of oncology Aug, 2009 | Pubmed ID: 19578743
Circulating tumor cell analysis: technical and statistical considerations for application to the clinic.
Journal of oncology , 2010 | Pubmed ID: 20049168
Deletion of the thrombin cleavage domain of osteopontin mediates breast cancer cell adhesion, proteolytic activity, tumorgenicity, and metastasis.
BMC cancer , 2011 | Pubmed ID: 21247495
Migratory strategies of normal and malignant stem cells.
Methods in molecular biology (Clifton, N.J.) , 2011 | Pubmed ID: 21618081
Image cytometry analysis of circulating tumor cells.
Methods in cell biology , 2011 | Pubmed ID: 21704842
The Role of Cancer Stem Cells in the Organ Tropism of Breast Cancer Metastasis: A Mechanistic Balance between the "Seed" and the "Soil"?
International journal of breast cancer , 2012 | Pubmed ID: 22295241
User-defined protein marker assay development for characterization of circulating tumor cells using the CellSearch® system.
Cytometry. Part A : the journal of the International Society for Analytical Cytology Nov, 2012 | Pubmed ID: 22899576
Recent advances in the molecular characterization of circulating tumor cells.
Cancers , 2014 | Pubmed ID: 24633084
Lung-derived factors mediate breast cancer cell migration through CD44 receptor-ligand interactions in a novel ex vivo system for analysis of organ-specific soluble proteins.
Neoplasia (New York, N.Y.) Feb, 2014 | Pubmed ID: 24709425
Aldehyde dehydrogenase as a marker and functional mediator of metastasis in solid tumors.
Clinical & experimental metastasis Jan, 2016 | Pubmed ID: 26445849
Central, But Not Peripheral, Circulating Tumor Cells are Prognostic in Patients Undergoing Resection of Colorectal Cancer Liver Metastases.
Annals of surgical oncology Jul, 2016 | Pubmed ID: 26714949
Circulating Tumor Cells (CTC) and Cell-Free DNA (cfDNA) Workshop 2016: Scientific Opportunities and Logistics for Cancer Clinical Trial Incorporation.
International journal of molecular sciences Sep, 2016 | Pubmed ID: 27618023
Epithelial-to-mesenchymal transition leads to disease-stage differences in circulating tumor cell detection and metastasis in pre-clinical models of prostate cancer.
Oncotarget Nov, 2016 | Pubmed ID: 27764810
Soluble bone-derived osteopontin promotes migration and stem-like behavior of breast cancer cells.
PloS one , 2017 | Pubmed ID: 28498874
Differential Functional Roles of ALDH1A1 and ALDH1A3 in Mediating Metastatic Behavior and Therapy Resistance of Human Breast Cancer Cells.
International journal of molecular sciences Sep, 2017 | Pubmed ID: 28937653
Circulating Tumor Cells and Implications of the Epithelial-to-Mesenchymal Transition.
Advances in clinical chemistry , 2018 | Pubmed ID: 29304900
Self-assembled amphiphilic zein-lactoferrin micelles for tumor targeted co-delivery of rapamycin and wogonin to breast cancer.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V Jul, 2018 | Pubmed ID: 29689288
Circulating Tumor Cell Analysis in Preclinical Mouse Models of Metastasis.
Diagnostics (Basel, Switzerland) Apr, 2018 | Pubmed ID: 29710776
Assessment of the Validity of Nuclear-Localized Androgen Receptor Splice Variant 7 in Circulating Tumor Cells as a Predictive Biomarker for Castration-Resistant Prostate Cancer.
JAMA oncology 09, 2018 | Pubmed ID: 29955787
Magnetically Guided Self-Assembled Protein Micelles for Enhanced Delivery of Dasatinib to Human Triple-Negative Breast Cancer Cells.
Journal of pharmaceutical sciences 05, 2019 | Pubmed ID: 30528944
A Phase II Study of PX-866 in Patients With Recurrent or Metastatic Castration-resistant Prostate Cancer: Canadian Cancer Trials Group Study IND205.
Clinical genitourinary cancer 06, 2019 | Pubmed ID: 31056399
Molecular Mechanisms of Breast Cancer Metastasis to the Lung: Clinical and Experimental Perspectives.
International journal of molecular sciences May, 2019 | Pubmed ID: 31071959
On-Chip Preparation of Amphiphilic Nanomicelles-in-Sodium Alginate Spheroids as a Novel Platform Against Triple-Negative Human Breast Cancer Cells: Fabrication, Study of Microfluidics Flow Hydrodynamics and Proof of Concept for Anticancer and Drug Delivery Applications.
Journal of pharmaceutical sciences 11, 2019 | Pubmed ID: 31351864
Role of the Microenvironment in Regulating Normal and Cancer Stem Cell Activity: Implications for Breast Cancer Progression and Therapy Response.
Cancers Aug, 2019 | Pubmed ID: 31450577
1London Regional Cancer Program, London Health Sciences Centre,
2Department of Anatomy & Cell Biology, Schulich School of Medicine and Dentistry, Western University,
3Special Hematology/Flow Cytometry, London Health Sciences Centre,
4, Lawson Health Research Institute,
5Department of Oncology, Western University
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