David S. Warner

Ambulatory discharge after long-acting peripheral nerve blockade: 2382 blocks with ropivacaine.

Peripheral nerve blockade with long-acting local anesthetics: a survey of the Society for Ambulatory Anesthesia.

Apolipoprotein E affects the central nervous system response to injury and the development of cerebral edema.

A randomized, double-blind comparison of ondansetron versus placebo for prevention of nausea and vomiting after infratentorial craniotomy.

Pharmacological correction of hypothermic P(50) shift does not alter outcome from focal cerebral ischemia in rats.

Differential cerebral gene expression during cardiopulmonary bypass in the rat: evidence for apoptosis?

Mouse model of subarachnoid hemorrhage associated cerebral vasospasm: methodological analysis.

Allopregnanolone attenuates N-methyl-D-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture.

Brain oxygenation and energy metabolism: part I-biological function and pathophysiology.

Attenuation of cerebral vasospasm after subarachnoid hemorrhage in mice overexpressing extracellular superoxide dismutase.

Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia.

Paravertebral somatic nerve block compared with peripheral nerve blocks for outpatient inguinal herniorrhaphy.

A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke.

Serum von Willebrand factor, matrix metalloproteinase-9, and vascular endothelial growth factor levels predict the onset of cerebral vasospasm after aneurysmal subarachnoid hemorrhage.

Apolipoprotein E protects against NMDA excitotoxicity.

Simvastatin increases endothelial nitric oxide synthase and ameliorates cerebral vasospasm resulting from subarachnoid hemorrhage.

A comparison of the remifentanil and fentanyl adverse effect profile in a multicenter phase IV study.

Hemodynamic effects of metalloporphyrin catalytic antioxidants: structure-activity relationships and species specificity.

Possible role for vascular cell proliferation in cerebral vasospasm after subarachnoid hemorrhage.

The difficulties of ambulatory interscalene and intra-articular infusions for rotator cuff surgery: a preliminary report.

Catalytic Antioxidants as Novel Pharmacologic Approaches to Treatment of Ischemic Brain Injury.

gamma-Aminobutyric acid-A receptors contribute to isoflurane neuroprotection in organotypic hippocampal cultures.

Apolipoprotein E protects against oxidative stress in mixed neuronal-glial cell cultures by reducing glutamate toxicity.

APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response.

The neuroprotective effect of xenon administration during transient middle cerebral artery occlusion in mice.

Altered perceptions after upper and lower extremity blocks: an initial investigation.

Severe hypotension is not essential for isoflurane neuroprotection against forebrain ischemia in mice.

Pharmacologic protection from ischemic neuronal injury.

Perioperative neuroprotection: are we asking the right questions?

Effects of isoflurane versus fentanyl-nitrous oxide anesthesia on long-term outcome from severe forebrain ischemia in the rat.

A no-laminectomy spinal cord compression injury model in mice.

Mouse spinal cord compression injury is ameliorated by intrathecal cationic manganese(III) porphyrin catalytic antioxidant therapy.

Oxidants, antioxidants and the ischemic brain.

Intraischemic nitrous oxide alters neither neurologic nor histologic outcome: a comparison with dizocilpine.

Treatment of traumatic brain injury: one size does not fit all.

Changes in magnetization transfer MRI correlate with spreading depression-induced astroglial reactivity and increased protein expression in mice.

Anesthetics provide limited but real protection against acute brain injury.

Apoptosis is not enhanced in primary mixed neuronal/glial cultures protected by isoflurane against N-methyl-D-aspartate excitotoxicity.

A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injury.

Analysis of the brain bioavailability of peripherally administered magnesium sulfate: A study in humans with acute brain injury undergoing prolonged induced hypermagnesemia.

Intrathecal administration of a novel apoE-derived therapeutic peptide improves outcome following perinatal hypoxic-ischemic injury.

A retrospective analysis of a remifentanil/propofol general anesthetic for craniotomy before awake functional brain mapping.

Simvastatin reduces vasospasm after aneurysmal subarachnoid hemorrhage: results of a pilot randomized clinical trial.

Isoflurane-induced neuronal degeneration: an evaluation in organotypic hippocampal slice cultures.

Magnesium neuroprotection is limited in humans with acute brain injury.

Peripheral nerve block techniques for ambulatory surgery.

The effect of age on sciatic nerve block duration.

Effects of a manganese (III) porphyrin catalytic antioxidant in a mouse closed head injury model.

A comparison of hyperbaric oxygen versus hypoxic cerebral preconditioning in neonatal rats.

A novel apoE-derived therapeutic reduces vasospasm and improves outcome in a murine model of subarachnoid hemorrhage.

Changing outcome from aneurysmal subarachnoid hemorrhage: another step closer.

Induction of hypothermia after intraoperative hypoxic brain insult.

Cardiac glycosides provide neuroprotection against ischemic stroke: discovery by a brain slice-based compound screening platform.

Selective gamma-aminobutyric acid type A receptor antagonism reverses isoflurane ischemic neuroprotection.

Levetiracetam is neuroprotective in murine models of closed head injury and subarachnoid hemorrhage.

NMDA-induced apoptosis in mixed neuronal/glial cortical cell cultures: the effects of isoflurane and dizocilpine.

Dissociation between vasospasm and functional improvement in a murine model of subarachnoid hemorrhage.

Isoflurane provides long-term protection against focal cerebral ischemia in the rat.

Superparamagnetic iron oxide labeling and transplantation of adipose-derived stem cells in middle cerebral artery occlusion-injured mice.

Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury.

Transient global cerebral ischemia induces a massive increase in protein sumoylation.

Preclinical models of intracerebral hemorrhage: a translational perspective.

Hypertonic saline for craniotomy?

Statins in acute brain injury: getting the cart before the horse.

Transient focal cerebral ischemia induces a dramatic activation of small ubiquitin-like modifier conjugation.

Cerebral ischemia/stroke and small ubiquitin-like modifier (SUMO) conjugation--a new target for therapeutic intervention?

Long-term cognitive dysfunction following experimental subarachnoid hemorrhage: new perspectives.

The use of S100B as a biomarker in subarachnoid hemorrhage: clarity in its promise and limits.

2008 in review: advancing medicine in anesthesiology.

Filling in the blanks.

Perioperative hypothermia: use and therapeutic implications.

Effect of lipophilicity of Mn (III) ortho N-alkylpyridyl- and diortho N, N'-diethylimidazolylporphyrins in two in-vitro models of oxygen and glucose deprivation-induced neuronal death.

Drowning: a cry for help.

Oxygen and glucose deprivation in an organotypic hippocampal slice model of the developing rat brain: the effects on N-methyl-D-aspartate subunit composition.

Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat.

Simvastatin treatment duration and cognitive preservation in experimental subarachnoid hemorrhage.

Metalloporphyrin antioxidants ameliorate normal tissue radiation damage in rat brain.

Development of a simplified spinal cord ischemia model in mice.

Adenosine-induced transient asystole for intracranial aneurysm surgery: a retrospective review.

Pharmacologically augmented S-nitrosylated hemoglobin improves recovery from murine subarachnoid hemorrhage.

Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrins.

Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage.

Statins improve outcome in murine models of intracranial hemorrhage and traumatic brain injury: A translational approach.

A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity.

Lack of evidence for a remote effect of renal ischemia/reperfusion acute kidney injury on outcome from temporary focal cerebral ischemia in the rat.

Brain resuscitation in the drowning victim.

Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators.

Xenon neuroprotection in experimental stroke: interactions with hypothermia and intracerebral hemorrhage.

Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP5+.

Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4.

Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology.

Metalloporphyrins as therapeutic catalytic oxidoreductants in central nervous system disorders.

Drowning resuscitation requires another state of mind.

Mr. Piano Man: reflections on the life of physician, scientist, and humanitarian, William L. Young, MD (1954-2013).

Volatile anesthetic sedation during therapeutic hypothermia after cardiac arrest in the ICU: a journey of a thousand miles begins with a single step.

Anesthetic Neuroprotection: Antecedents and An Appraisal of Preclinical and Clinical Data Quality.

ApoE mimetic ameliorates motor deficit and tissue damage in rat spinal cord injury.