Manfred Auer

Fluorescent Fingerprinting of Molecular Recognition Landscapes J.J.L. thanks Wolfgang Rettig (Humboldt University) for his generosity during the preparation of this manuscript and the Uebbing Foundation for support. M.A. thanks Jan E. de Vries for continuous support and encouragement.

Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli.

Three-dimensional crystallization of the Escherichia coli glycerol-3-phosphate transporter: a member of the major facilitator superfamily.

Volumetric feature extraction and visualization of tomographic molecular imaging.

Confocal fluorescence detection expanded to UV excitation: the first continuous fluorimetric assay of human steroid sulfatase in nanoliter volume.

The chemical hunt for the identification of drugable targets.

mRNA openers and closers: modulating AU-rich element-controlled mRNA stability by a molecular switch in mRNA secondary structure.

The effect of RNA secondary structures on RNA-ligand binding and the modifier RNA mechanism: a quantitative model.

Multi-photon excitation of intrinsic protein fluorescence and its application to pharmaceutical drug screening.

Structural and biophysical characterization of the EphB4*ephrinB2 protein-protein interaction and receptor specificity.

High-pressure freezing, cellular tomography, and structural cell biology.

Beyond dimerization: a membrane-dependent activation model for interleukin-4 receptor-mediated signalling.

Pseudomonas aeruginosa forms biofilms in acute infection independent of cell-to-cell signaling.

Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR.

Genetic evidence for three unique components in primary cell-wall cellulose synthase complexes in Arabidopsis.

Electron tomography: a 3D view of the subcellular world.

Three-dimensional architecture of hair-bundle linkages revealed by electron-microscopic tomography.

Covalent fluorescence labeling of His-tagged proteins on the surface of living cells.

Single-bead, single-molecule, single-cell fluorescence: technologies for drug screening and target validation.

Natural acidophilic biofilm communities reflect distinct organismal and functional organization.

Terminal adenosyl transferase activity of posttranscriptional regulator HuR revealed by confocal on-bead screening.

Electron tomography, three-dimensional Fourier analysis and colour prediction of a three-dimensional amorphous biophotonic nanostructure.

Three-dimensional macromolecular organization of cryofixed Myxococcus xanthus biofilms as revealed by electron microscopic tomography.

A highly potent and cellularly active beta-peptidic inhibitor of the p53/hDM2 interaction.

Confocal nanoscanning, bead picking (CONA): PickoScreen microscopes for automated and quantitative screening of one-bead one-compound libraries.

Single bead labeling method for combining confocal fluorescence on-bead screening and solution validation of tagged one-bead one-compound libraries.

Mutations in UDP-Glucose:sterol glucosyltransferase in Arabidopsis cause transparent testa phenotype and suberization defect in seeds.

Plant cell walls throughout evolution: towards a molecular understanding of their design principles.

Comparison of dilute acid and ionic liquid pretreatment of switchgrass: Biomass recalcitrance, delignification and enzymatic saccharification.

The x-ray crystal structure of the first RNA recognition motif and site-directed mutagenesis suggest a possible HuR redox sensing mechanism.

Biofilms: structures that may facilitate cell-cell interactions.

Identification of a small molecule inhibitor of importin β mediated nuclear import by confocal on-bead screening of tagged one-bead one-compound libraries.

Analysis of protein-small molecule interactions by microscale equilibrium dialysis and its application as a secondary confirmation method for on-bead screening.

Deep-sea oil plume enriches indigenous oil-degrading bacteria.

High-throughput enzymatic hydrolysis of lignocellulosic biomass via in-situ regeneration.

A direct way of redox sensing.

The cooperative activities of CSLD2, CSLD3, and CSLD5 are required for normal Arabidopsis development.

Surface multiheme c-type cytochromes from Thermincola potens and implications for respiratory metal reduction by Gram-positive bacteria.

Mammary collective cell migration involves transient loss of epithelial features and individual cell migration within the epithelium.

Loss of Cellulose synthase-like F6 function affects mixed-linkage glucan deposition, cell wall mechanical properties, and defense responses in vegetative tissues of rice.

Isolation and proteomic characterization of the Arabidopsis Golgi defines functional and novel components involved in plant cell wall biosynthesis.

Deep-sea bacteria enriched by oil and dispersant from the Deepwater Horizon spill.

Perivascular-resident macrophage-like melanocytes in the inner ear are essential for the integrity of the intrastrial fluid-blood barrier.

On-bead screens sample narrower affinity ranges of protein-ligand interactions compared to equivalent solution assays.

Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection.

Understanding changes in lignin of Panicum virgatum and Eucalyptus globulus as a function of ionic liquid pretreatment.

Engineering secondary cell wall deposition in plants.

Inactivation of OsIRX10 leads to decreased xylan content in ricestem cell walls and improved biomass saccharification.

Engineering of plants with improved properties as biofuels feedstocks by vessel-specific complementation of xylan biosynthesis mutants.

The role of bacterial outer membrane vesicles for intra- and interspecies delivery.

Towards mimicking short linear peptide motifs: identification of new mixed α,β-peptidomimetic ligands for SLAM-Associated Protein (SAP) by confocal on-bead screening.

Molecular architecture of the chick vestibular hair bundle.

Survey of renewable chemicals produced from lignocellulosic biomass during ionic liquid pretreatment.

Isolation and culture of endothelial cells, pericytes and perivascular resident macrophage-like melanocytes from the young mouse ear.

Three Novel Rice Genes Closely Related to the Arabidopsis IRX9, IRX9L, and IRX14 Genes and Their Roles in Xylan Biosynthesis.

Correlative microscopy for phylogenetic and ultrastructural characterization of microbial communities.

Community dynamics of cellulose-adapted thermophilic bacterial consortia.

Bacterial social networks: structure and composition of Myxococcus xanthus outer membrane vesicle chains.

CSBB-ConeExclusion, adapting structure based solution virtual screening to libraries on solid support.

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin.

ACF7 is a hair-bundle antecedent, positioned to integrate cuticular plate actin and somatic tubulin.

High-throughput chemical screening for antivirulence developmental phenotypes in Trypanosoma brucei.

Biomimetic virus-based colourimetric sensors.

Twist1-induced dissemination preserves epithelial identity and requires E-cadherin.

Exploring the role of CheA3 in Desulfovibrio vulgaris Hildenborough motility.

Identification and X-ray co-crystal structure of a small-molecule activator of LFA-1-ICAM-1 binding.

Novel 1:1 labeling and purification process for C-terminal thioester and single cysteine recombinant proteins using generic peptidic toolbox reagents.

A loss of function analysis of host factors influencing Vaccinia virus replication by RNA interference.

Death and transfiguration in static Staphylococcus epidermidis cultures.

Cellulosic biomass pretreatment and sugar yields as a function of biomass particle size.

Temporal dynamics of fibrolytic and methanogenic rumen microorganisms during in situ incubation of switchgrass determined by 16S rRNA gene profiling.

Electron tomography unravels new insights into fiber cell wall nanostructure; exploring 3D macromolecular biopolymeric nano-architecture of spruce fiber secondary walls.