Caroline Bonnans

Lipoxins are potential endogenous antiinflammatory mediators in asthma.

15-lipoxygenase: a Janus enzyme?

Lipoxin A4 stimulates a cytosolic Ca2+ increase in human bronchial epithelium.

Severe asthma is associated with a loss of LX4, an endogenous anti-inflammatory compound.

Cyclooxygenase 2 plays a pivotal role in the resolution of acute lung injury.

Diminished lipoxin biosynthesis in severe asthma.

Lipoxin A(4) regulates bronchial epithelial cell responses to acid injury.

Regulation of phosphatidylinositol 3-kinase by polyisoprenyl phosphates in neutrophil-mediated tissue injury.

Lipid mediators as agonists for the resolution of acute lung inflammation and injury.

Synthesis and anti-inflammatory effect of lipoxins in human airway epithelial cells.

Modulation of human airway smooth muscle migration by lipid mediators and Th-2 cytokines.

Thiazolidinediones induce proliferation of human bronchial epithelial cells through the GPR40 receptor.

The wnt target jagged-1 mediates the activation of notch signaling by progastrin in human colorectal cancer cells.

Symplekin promotes tumorigenicity by up-regulating claudin-2 expression.

Pregnane X Receptor (PXR) expression in colorectal cancer cells restricts irinotecan chemosensitivity through enhanced SN-38 glucuronidation.

The endogenous pro-resolving mediators lipoxin A4 and resolvin E1 preserve organ function in allograft rejection.

Essential requirement for β-arrestin2 in mouse intestinal tumors with elevated Wnt signaling.

An ex vivo model of severe asthma using reconstituted human bronchial epithelium.