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Department of Molecular Medicine
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Incorporation of oxidatively modified 2'-deoxynucleotide triphosphates by HIV-1 RT on RNA and DNA templates.
Chemical research in toxicology May, 2002 | Pubmed ID: 12018986
A structural model of the constitutive androstane receptor defines novel interactions that mediate ligand-independent activity.
Molecular and cellular biology Aug, 2002 | Pubmed ID: 12101224
Stability, miscoding potential, and repair of 2'-deoxyxanthosine in DNA: implications for nitric oxide-induced mutagenesis.
Biochemistry Apr, 2003 | Pubmed ID: 12653565
DNA damage and mutations induced by arachidonic acid peroxidation.
Biochemistry Dec, 2003 | Pubmed ID: 14690412
Peroxyl radical mediated oxidative DNA base damage: implications for lipid peroxidation induced mutagenesis.
Biochemistry Dec, 2004 | Pubmed ID: 15581346
Novel conjugates of epitope fusion peptides with CpG-ODN display enhanced immunogenicity and HIV recognition.
Vaccine May, 2005 | Pubmed ID: 15837369
Nucleotide excision repair eliminates unique DNA-protein cross-links from mammalian cells.
The Journal of biological chemistry Aug, 2007 | Pubmed ID: 17507378
Advanced glycation end products of DNA: quantification of N2-(1-Carboxyethyl)-2'-deoxyguanosine in biological samples by liquid chromatography electrospray ionization tandem mass spectrometry.
Chemical research in toxicology Nov, 2008 | Pubmed ID: 18808156
Nucleotide sequence context influences HIV replication fidelity by modulating reverse transcriptase binding and product release.
Bioscience trends Aug, 2007 | Pubmed ID: 20103867
Mutagenic potential of DNA glycation: miscoding by (R)- and (S)-N2-(1-carboxyethyl)-2'-deoxyguanosine.
Biochemistry Mar, 2010 | Pubmed ID: 20143879
Mutagenesis and repair induced by the DNA advanced glycation end product N2-1-(carboxyethyl)-2'-deoxyguanosine in human cells.
Biochemistry Mar, 2011 | Pubmed ID: 21355561
Differential cytostatic and cytotoxic action of Metallocorroles against human cancer cells: potential platforms for anticancer drug development.
Chemical research in toxicology Feb, 2012 | Pubmed ID: 22185566
Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal.
The Journal of clinical investigation Jun, 2012 | Pubmed ID: 22585572
Genetic mutations and tissue type lead to heterogeneous metabolic profiles in tumors.
Neurosurgery Jun, 2012 | Pubmed ID: 22596009
Glyoxalase 1 and its substrate methylglyoxal are novel regulators of seizure susceptibility.
Epilepsia Apr, 2013 | Pubmed ID: 23409935
Human breast cancer metastases to the brain display GABAergic properties in the neural niche.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2014 | Pubmed ID: 24395782
Role of the neural niche in brain metastatic cancer.
Cancer research Aug, 2014 | Pubmed ID: 25035392
A cytotoxic and cytostatic gold(III) corrole.
Chemical communications (Cambridge, England) Nov, 2014 | Pubmed ID: 25252099
Beckman Research Institute of the City of Hope
Grace Y. Tang1,
Melanie A. Pribisko1,
Ryan K. Henning1,
Punnajit Lim2,
John Termini2,
Harry B. Gray1,
Robert H. Grubbs1
1Division of Chemistry and Chemical Engineering, California Institute of Technology,
2Department of Molecular Medicine, Beckman Research Institute of the City of Hope
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