Tom C. Karagiannis

Epigenetic changes activate widespread signals in response to double-strand breaks.

Plasmid DNA breakage by decay of DNA-associated Auger electron emitters: approaches to analysis of experimental data.

siRNAs: mechanism of RNA interference, in vivo and potential clinical applications.

Radio- and chemo-sensitization of human erythroleukemic K562 cells by the histone deacetylase inhibitor Trichostatin A.

RNA interference and potential therapeutic applications of short interfering RNAs.

The histone deacetylase inhibitor, Trichostatin A, enhances radiation sensitivity and accumulation of gammaH2A.X.

The paradox of histone deacetylase inhibitor-mediated modulation of cellular responses to radiation.

DNA targeted UVA photosensitization: characterization of an extremely photopotent iodinated minor groove binding DNA ligand.

Radioimmunotherapy: Principles, current trends and future directions.

Receptor-mediated DNA-targeted photoimmunotherapy.

Comparison of different classes of radionuclides for potential use in radioimmunotherapy.

Clinical potential of histone deacetylase inhibitors as stand alone therapeutics and in combination with other chemotherapeutics or radiotherapy for cancer.

The epigenetic modifier, valproic acid, enhances radiation sensitivity.

Antibody-based cancer treatment with ultra-short range Auger electron-emitting radionuclides: dual receptor and DNA targeting strategies.

Effect of valproic acid on radiation-induced DNA damage in euchromatic and heterochromatic compartments.

gamma-radiation-induced gammaH2AX formation occurs preferentially in actively transcribing euchromatic loci.

GammaH2AX as a molecular marker of aging and disease.

Methylproamine protects against ionizing radiation by preventing DNA double-strand breaks.

Trichostatin A accentuates doxorubicin-induced hypertrophy in cardiac myocytes.

Protection by methylproamine of irradiated human keratinocytes correlates with reduction of DNA damage.

Genetic and epigenetic events in diabetic wound healing.

Epigenome targeting by probiotic metabolites.

Double-strand breaks and the concept of short- and long-term epigenetic memory.

Evaluation of the efficacy of radiation-modifying compounds using γH2AX as a molecular marker of DNA double-strand breaks.

Effects of oral intake of water in patients with oropharyngeal dysphagia.

Photosensitization by iodinated DNA minor groove binding ligands: Evaluation of DNA double-strand break induction and repair.

Molecular model of naphthalene-induced DNA damage in the murine lung.

Histone deacetylase inhibitors augment doxorubicin-induced DNA damage in cardiomyocytes.

Chromatin modifying agents - the cutting edge of anticancer therapy.

Investigation into the biological properties of the olive polyphenol, hydroxytyrosol: mechanistic insights by genome-wide mRNA-Seq analysis.

Potential non-oncological applications of histone deacetylase inhibitors.

Protective effects of valproic acid against airway hyperresponsiveness and airway remodeling in a mouse model of allergic airways disease.

Utility of γH2AX as a Molecular Marker of DNA Double-Strand Breaks in Nuclear Medicine: Applications to Radionuclide Therapy Employing Auger Electron-Emitting Isotopes.

Influence of Natural and Synthetic Histone Deacetylase Inhibitors on Chromatin.

Histone deacetylases and their role in asthma.