Katrin Zeilinger

Three-dimensional co-culture of primary human liver cells in bioreactors for in vitro drug studies: effects of the initial cell quality on the long-term maintenance of hepatocyte-specific functions.

Recovery of preservation-injured primary human hepatocytes and nonparenchymal cells to tissuelike structures in large-scale bioreactors for liver support: an initial transmission electron microscopy study.

Porcine endogenous retroviruses: no infection in patients treated with a bioreactor based on porcine liver cells.

Extracorporeal liver support based on primary human liver cells and albumin dialysis--treatment of a patient with primary graft non-function.

Use of primary human liver cells originating from discarded grafts in a bioreactor for liver support therapy and the prospects of culturing adult liver stem cells in bioreactors: a morphologic study.

Time course of primary liver cell reorganization in three-dimensional high-density bioreactors for extracorporeal liver support: an immunohistochemical and ultrastructural study.

Evaluation of primary human liver cells in bioreactor cultures for extracorporeal liver support on the basis of urea production.

Bioartificial liver systems: why, what, whither?

Evaluation and optimization of hepatocyte culture media factors by design of experiments (DoE) methodology.

Isolation and characterization of adult human liver progenitors from ischemic liver tissue derived from therapeutic hepatectomies.

Effect of human patient plasma ex vivo treatment on gene expression and progenitor cell activation of primary human liver cells in multi-compartment 3D perfusion bioreactors for extra-corporeal liver support.

Dynamic 3D culture promotes spontaneous embryonic stem cell differentiation in vitro.

The Characterization Tool: A knowledge-based stem cell, differentiated cell, and tissue database with a web-based analysis front-end.

Molecular characterization of cultured adult human liver progenitor cells.

Three-dimensional perfusion bioreactor culture supports differentiation of human fetal liver cells.

Interwoven four-compartment capillary membrane technology for three-dimensional perfusion with decentralized mass exchange to scale up embryonic stem cell culture.

Lidocaine/monoethylglycinexylidide test, galactose elimination test, and sorbitol elimination test for metabolic assessment of liver cell bioreactors.

HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro.

Feasibility of using sodium chloride as a tracer for the characterization of the distribution of matter in complex multi-compartment 3D bioreactors for stem cell culture.

Optimization of a serum-free culture medium for mouse embryonic stem cells using design of experiments (DoE) methodology.

Scaling down of a clinical three-dimensional perfusion multicompartment hollow fiber liver bioreactor developed for extracorporeal liver support to an analytical scale device useful for hepatic pharmacological in vitro studies.

Cytochrome P450-dependent metabolism in HepaRG cells cultured in a dynamic three-dimensional bioreactor.

In-depth physiological characterization of primary human hepatocytes in a 3D hollow-fiber bioreactor.

Cell therapeutic options in liver diseases: cell types, medical devices and regulatory issues.

Perfusion circuit concepts for hollow-fiber bioreactors used as in vitro cell production systems or ex vivo bioartificial organs.

Toward preclinical predictive drug testing for metabolism and hepatotoxicity by using in vitro models derived from human embryonic stem cells and human cell lines - a report on the Vitrocellomics EU-project.

Compartmental hollow fiber capillary membrane-based bioreactor technology for in vitro studies on red blood cell lineage direction of hematopoietic stem cells.

Active wound dressing with artificial capillaries for temporary wound irrigation and skin cell supply.

Analysis of drug metabolism activities in a miniaturized liver cell bioreactor for use in pharmacological studies.

Phenotypical characterization of 6-21-week gestational age human dermis and epidermal cell isolation methods for in vitro studies on epidermal progenitors.

Serum-free culture of primary human hepatocytes in a miniaturized hollow-fibre membrane bioreactor for pharmacological in vitro studies.

State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology.

Featured Article: Isolation, characterization, and cultivation of human hepatocytes and non-parenchymal liver cells.

Feasibility study of an active wound dressing based on hollow fiber membranes in a porcine wound model.

Periodic harvesting of embryonic stem cells from a hollow-fiber membrane based four-compartment bioreactor.

Subtoxic Concentrations of Hepatotoxic Drugs Lead to Kupffer Cell Activation in a Human In Vitro Liver Model: An Approach to Study DILI.