Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis

Hip weakness is a common symptom affecting walking ability in people with multiple sclerosis (MS). It is known that resistance strength training (RST) can ...

Kennedy Krieger Institute

Johns Hopkins University School of Medicine

Attenzione menomazioni seguito di grave trauma cranico (TBI) sono comuni e possono portare a ridotta mobilit&agrave; funzionale ed equilibrio, cos&igrave; come Deficit nei movimenti automatici in precedenza come camminare e salire scale. Lo scopo di questo studio era di determinare la fattibilit&agrave; e potenziale valore di incorporare un cognitivo-motore doppio compito formativo in terapia fisica per un paziente con un grave trauma cranico.

Doppio compito traumatico di formazione per l&#39;equilibrio e la mobilit&agrave; di una persona con gravi lesioni del cervello: un caso di studio.

Attentional impairments following severe traumatic brain injury (TBI) are common and can lead to decreased functional mobility and balance, as well as deficits in previously automatic movements such as walking and stair climbing. The purpose of this case study was to determine the feasibility and potential value of incorporating a cognitive-motor dual-task training program into physical therapy for a patient with a severe TBI.

Dual-task training for balance and mobility in a person with severe traumatic brain injury: a case study.

Troubles attentionnels suite grave traumatisme cr&acirc;nien (TCC) sont fr&eacute;quentes et peuvent conduire &agrave; la diminution de la mobilit&eacute; fonctionnelle et &eacute;quilibre, ainsi que des d&eacute;ficits en mouvements pr&eacute;c&eacute;demment automatiques comme marcher et &agrave; monter des escaliers. Le but de cette &eacute;tude de cas &eacute;tait de d&eacute;terminer la faisabilit&eacute; et le potentiel de valeur d&#39;int&eacute;grer un programme de formation de double t&acirc;che cognitive-moteur physioth&eacute;rapie chez un patient pr&eacute;sentant un TCC s&eacute;v&egrave;re.

Formation pour l&#39;&eacute;quilibre et la mobilit&eacute; chez une personne souffrant de graves traumatismes double t&acirc;che Apoplexie c&eacute;r&eacute;brale : une &eacute;tude de cas.

Clinical intervention trials in people with Huntington disease (HD) have been limited by a lack of reliable and appropriate outcome measures.

Reliability and minimal detectable change of physical performance measures in individuals with pre-manifest and manifest Huntington disease.

To investigate the feasibility, acceptability, and safety of a supervised video game exercise program administered via Dance Dance Revolution in individuals with Huntington's disease.

Video game play (Dance Dance Revolution) as a potential exercise therapy in Huntington's disease: a controlled clinical trial.

Static posture imbalance and gait dysfunction are common in individuals with multiple sclerosis (MS). Although the impact of strength and static balance on walking has been examined, the impact of dynamic standing balance on walking in MS remains unclear.

The impact of dynamic balance measures on walking performance in multiple sclerosis.

Individuals with Huntington's disease (HD) experience balance and gait problems that lead to falls. Clinicians currently have very little information about the reliability and validity of outcome measures to determine the efficacy of interventions that aim to reduce balance and gait impairments in HD. This study examined the reliability and concurrent validity of spatiotemporal gait measures, the Tinetti Mobility Test (TMT), Four Square Step Test (FSST), and Activities-specific Balance Confidence (ABC) Scale in individuals with HD.

Clinimetric properties of the Tinetti Mobility Test, Four Square Step Test, Activities-specific Balance Confidence Scale, and spatiotemporal gait measures in individuals with Huntington's disease.

Chorea may contribute to balance problems and walking difficulties that lead to higher fall rates in individuals with Huntington's disease (HD). Few studies have examined the effects of tetrabenazine (TBZ), an anti-choreic drug, on function and mobility in HD. The purpose of this study was to compare: 1) gait measures in forward walking, 2) balance and mobility measures, and 3) hand and forearm function measures on and off TBZ. We hypothesized that use of TBZ would improve gait, transfers and hand and forearm function. Eleven individuals with HD on stable doses of TBZ were evaluated while off medication and again following resumption of medication. Significant improvements were found on the Unified Huntington's Disease Rating Scale (UHDRS) motor scores, Tinetti Mobility Test (TMT) total (t=4.20, p=0.002) and balance subscale (t=-4.61, p=0.001) scores, and the Five Times Sit-to-Stand test (5TSST, t=3.20, p=.009) when on-TBZ compared to off-TBZ. Spatiotemporal gait measures, the Six Condition Romberg test, and UHDRS hand and forearm function items were not changed by TBZ use. Improved TMT and 5TSST performance when on drug indicates that TBZ use may improve balance and functional mobility in individuals with HD.

Impact of tetrabenazine on gait and functional mobility in individuals with Huntington's disease.

Gait and balance dysfunction frequently occurs early in the multiple sclerosis (MS) disease course. Hence, we sought to determine the longitudinal relationships among quantitative measures of gait and balance in individuals with MS.

Longitudinal relationships among posturography and gait measures in multiple sclerosis.

Sports-related concussions are particularly common during adolescence, a time when even mild brain injuries may disrupt ongoing brain maturation and result in long-term complications. A recent focus on the consequences of repetitive concussions among professional athletes has prompted the development of several new experimental models in rodents, as well as the revision of guidelines for best management of sports concussions. Here, we consider the utility of rodent models to understand the functional consequences and pathobiology of concussions in the developing brain, identifying the unique behavioral and pathological signatures of concussive brain injuries. The impact of repetitive concussions on behavioral consequences and injury progression is also addressed. In particular, we focus on the epidemiological, clinical, and experimental evidence underlying current recommendations for physical and cognitive rest after concussion, and highlight key areas in which further research is needed. Lastly, we consider how best to promote recovery after injury, recognizing that optimally timed, activity-based rehabilitative strategies may hold promise for the adolescent athlete who has sustained single or repetitive concussions. The purpose of this review is to inform the clinical research community as it strives to develop and optimize evidence-based guidelines for the concussed adolescent, in terms of both acute and long-term management.

Repetitive concussions in adolescent athletes - translating clinical and experimental research into perspectives on rehabilitation strategies.

Deficits in motor-cognitive dual tasks (eg, walking while talking) are common in individuals with neurologic conditions. This review was conducted to determine the effectiveness of motor-cognitive dual-task training (DTT) compared with usual care on mobility and cognition in individuals with neurologic disorders.

Motor-Cognitive Dual-Task Training in Persons With Neurologic Disorders: A Systematic Review.

To examine the concurrent validity of the Six-Spot Step Test (SSST) with clinical measures of walking and spatiotemporal measures of gait in multiple sclerosis (MS), and to understand the utility of the SSST in individuals with both low and high levels of disability.

Nora Fritz

Motion Analysis Laboratory

Kennedy Krieger Institute

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis

Nora Fritz

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Motion Analysis Laboratory

Kennedy Krieger Institute

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis

Motion Analysis Laboratory