Scott Kitchen

Activation of CD8 T cells induces expression of CD4, which functions as a chemotactic receptor.

The CCR5 and CXCR4 coreceptors--central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection.

CD4 on CD8(+) T cells directly enhances effector function and is a target for HIV infection.

The CD4 molecule on CD8+ T lymphocytes directly enhances the immune response to viral and cellular antigens.

Rapid size dependent deletion of foreign gene sequences inserted into attenuated HIV-1 upon infection in vivo: implications for vaccine development.

Serum levels of the homeostatic B cell chemokine, CXCL13, are elevated during HIV infection.

T lineage differentiation from human embryonic stem cells.

CD4 expression on activated NK cells: ligation of CD4 induces cytokine expression and cell migration.

Enfuvirtide antiretroviral therapy in HIV-1 infection.

Generation of T lineage cells from human embryonic stem cells in a feeder free system.

Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice.

Macrophage differentiation from embryoid bodies derived from human embryonic stem cells.

CD40 ligand (CD154) incorporated into HIV virions induces activation-induced cytidine deaminase (AID) expression in human B lymphocytes.

Stem cell-based approaches to treating HIV infection.

Stem cell-based anti-HIV gene therapy.

In Vivo validation of a bioinformatics based tool to identify reduced replication capacity in HIV-1.

Pre-clinical evaluation of a 213Bi-labeled 2556 antibody to HIV-1 gp41 glycoprotein in HIV-1 mouse models as a reagent for HIV eradication.

In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells.

Stem-cell-based gene therapy for HIV infection.

CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection.

Validation of an HPV16-mediated carcinogenesis mouse model.

Engineering Cellular Resistance to HIV-1 Infection In Vivo Using a Dual Therapeutic Lentiviral Vector.

HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem Cells.

Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary.

Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling.

Type I and Type II Interferon Coordinately Regulate Suppressive Dendritic Cell Fate and Function during Viral Persistence.

HIV-1-Specific Chimeric Antigen Receptors Based on Broadly-Neutralizing Antibodies.

New approaches for the enhancement of chimeric antigen receptors for the treatment of HIV.

Lentiviral Vector-Based Dendritic Cell Vaccine Suppresses HIV Replication in Humanized Mice.