Jeffrey M. Peters

Hepatic regeneration in peroxisome proliferator-activated receptor alpha-null mice after partial hepatectomy.

Induction of CYP3A expression by dehydroepiandrosterone: involvement of the pregnane X receptor.

Targeted disruption of peroxisomal proliferator-activated receptor beta (delta) results in distinct gender differences in mouse brain phospholipid and esterified FA levels.

Effects of conjugated linoleic acid (CLA) on immune responses, body composition and stearoyl-CoA desaturase.

Bezafibrate is a dual ligand for PPARalpha and PPARbeta: studies using null mice.

Comprehensive gene expression analysis of peroxisome proliferator-treated immortalized hepatocytes: identification of peroxisome proliferator-activated receptor alpha-dependent growth regulatory genes.

PPARalpha agonist-induced rodent tumors: modes of action and human relevance.

Expression of base excision DNA repair genes is a sensitive biomarker for in vivo detection of chemical-induced chronic oxidative stress: identification of the molecular source of radicals responsible for DNA damage by peroxisome proliferators.

Peroxisome proliferator-activated receptor beta/delta regulates very low density lipoprotein production and catabolism in mice on a Western diet.

Peroxisome proliferator-activated receptor beta (delta)-dependent regulation of ubiquitin C expression contributes to attenuation of skin carcinogenesis.

Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis.

PPARgamma influences susceptibility to DMBA-induced mammary, ovarian and skin carcinogenesis.

Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated receptor-alpha.

PPARbeta/delta potentiates PPARgamma-stimulated adipocyte differentiation.

Activation of mouse and human peroxisome proliferator-activated receptors (PPARs) by phthalate monoesters.

The United States-Japan workshop on: The role of nuclear receptors in carcinogenesis.

Peroxisome proliferator-activated receptor alpha protects against alcohol-induced liver damage.

Role of peroxisome proliferator-activated receptor-alpha (PPARalpha) in bezafibrate-induced hepatocarcinogenesis and cholestasis.

PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine.

Regulation of human apoA-I by gemfibrozil and fenofibrate through selective peroxisome proliferator-activated receptor alpha modulation.

Peroxisome proliferator-activated receptor-beta/delta inhibits epidermal cell proliferation by down-regulation of kinase activity.

Differences in cell proliferation in rodent and human hepatic derived cell lines exposed to ciprofibrate.

Peroxisome proliferator-activated receptor-alpha and liver cancer: where do we stand?

Protective effects of a peroxisome proliferator-activated receptor-beta/delta agonist in experimental autoimmune encephalomyelitis.

The role of peroxisome proliferator-activated receptor-beta/delta in epithelial cell growth and differentiation.

Evidence that ligand binding is a key determinant of Ah receptor-mediated transcriptional activity.

The aryl hydrocarbon receptor directly regulates expression of the potent mitogen epiregulin.

The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR).

Alterations in skin and stratified epithelia by constitutively activated PPARalpha.

Inhibition of chemically induced skin carcinogenesis by sulindac is independent of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta).

PPARdelta regulates glucose metabolism and insulin sensitivity.

Ligand activation of peroxisome proliferator-activated receptor beta inhibits colon carcinogenesis.

PPARdelta status and mismatch repair mediated neoplasia in the mouse intestine.

Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity.

Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver.

Sustained formation of alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts in mouse liver by peroxisome proliferators is dependent upon peroxisome proliferator-activated receptor-alpha, but not NADPH oxidase.

Ligand activation of peroxisome proliferator-activated receptor-beta/delta(PPARbeta/delta) inhibits cell growth of human N/TERT-1 keratinocytes.

PPARalpha and effects of TCE.

The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta).

PPARbeta/delta protects against experimental colitis through a ligand-independent mechanism.

Deregulation of tumor angiogenesis and blockade of tumor growth in PPARbeta-deficient mice.

Transcriptional network governing the angiogenic switch in human pancreatic cancer.

Growth of transgenic RAF-induced lung adenomas is increased in mice with a disrupted PPARbeta/delta gene.

Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands do not potentiate growth of human cancer cell lines.

COX-2 suppresses tissue factor expression via endocannabinoid-directed PPARdelta activation.

Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signaling mechanisms.

Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver.

Peroxisome proliferator-activated receptor-beta/delta protects against chemically induced liver toxicity in mice.

Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands inhibit growth of UACC903 and MCF7 human cancer cell lines.

Quantitative expression patterns of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) protein in mice.

A Role for PPARbeta/delta in Tumor Stroma and Tumorigenesis.

Role of peroxisome-proliferator-activated receptor beta/delta (PPARbeta/delta) in gastrointestinal tract function and disease.

Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) attenuates carbon tetrachloride hepatotoxicity by downregulating proinflammatory gene expression.

Ligand activation of peroxisome proliferator-activated receptor-beta/delta inhibits cell proliferation in human HaCaT keratinocytes.

Peroxisome proliferator-activated receptor-delta agonist enhances vasculogenesis by regulating endothelial progenitor cells through genomic and nongenomic activations of the phosphatidylinositol 3-kinase/Akt pathway.

Nrf2- and PPAR alpha-mediated regulation of hepatic Mrp transporters after exposure to perfluorooctanoic acid and perfluorodecanoic acid.

Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta) inhibits chemically induced skin tumorigenesis.

Effect of ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in human lung cancer cell lines.

PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer.

Regulation of peroxisome proliferator-activated receptor-alpha by MDM2.

Regulation of peroxisome proliferator-activated receptors by e6-associated protein.

Differential hepatic effects of perfluorobutyrate mediated by mouse and human PPAR-alpha.

Regulation of peroxisome proliferator-activated receptor-beta/delta by the APC/beta-CATENIN pathway and nonsteroidal antiinflammatory drugs.

Sorting out the functional role(s) of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in cell proliferation and cancer.

Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) inhibits cell growth in a mouse mammary gland cancer cell line.

Ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase-2 enhances inhibition of skin tumorigenesis.

Regulation of oligodendrocyte progenitor cell maturation by PPARδ: effects on bone morphogenetic proteins.

A natural propenoic acid derivative activates peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta).

Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-beta/delta antagonist GSK3787.

Synthesis of isosteric selenium analog of the PPARbeta/delta agonist GW501516 and comparison of biological activity.

Effect of prenatal peroxisome proliferator-activated receptor alpha (PPARalpha) agonism on postnatal development.

Xenobiotic metabolism, disposition, and regulation by receptors: from biochemical phenomenon to predictors of major toxicities.

Chemoprevention of chemically induced skin tumorigenesis by ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase 2.

PPARβ/δ activation induces enteroendocrine L cell GLP-1 production.

Functional characterization of peroxisome proliferator-activated receptor-β/δ expression in colon cancer.

Stable over-expression of PPARβ/δ and PPARγ to examine receptor signaling in human HaCaT keratinocytes.

PPAR action in insulin resistance unraveled by metabolomics: potential clinical implications.

Why toxic equivalency factors are not suitable for perfluoroalkyl chemicals.

Immunomodulatory action of dietary fish oil and targeted deletion of intestinal epithelial cell PPARδ in inflammation-induced colon carcinogenesis.

NTP-CERHR expert panel report on the developmental toxicity of soy infant formula.

Dissecting the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) in colon, breast, and lung carcinogenesis.

The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention.

Peroxisome proliferator-activated receptor β/δ cross talks with E2F and attenuates mitosis in HRAS-expressing cells.

Modulation of gastrointestinal inflammation and colorectal tumorigenesis by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ).

A species difference in the peroxisome proliferator-activated receptor α-dependent response to the developmental effects of perfluorooctanoic acid.

Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4.

Metabolomics: an essential tool to understand the function of peroxisome proliferator-activated receptor alpha.

Cholestasis induces reversible accumulation of periplakin in mouse liver.

PPARβ/δ modulates ethanol-induced hepatic effects by decreasing pyridoxal kinase activity.

Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study.

Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis.

Targeting estrogen receptor-β for the prevention of nonmelanoma skin cancer.

Activation of peroxisome proliferator-activated receptor-β/δ (PPAR-β/δ) inhibits human breast cancer cell line tumorigenicity.

Modulation of aryl hydrocarbon receptor (AHR)-dependent signaling by peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in keratinocytes.

The nuclear receptor peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) promotes oncogene-induced cellular senescence through repression of endoplasmic reticulum stress.

Comparative in vivo and in vitro analysis of possible estrogenic effects of perfluorooctanoic acid.

M-CSF from Cancer Cells Induces Fatty Acid Synthase and PPARβ/δ Activation in Tumor Myeloid Cells, Leading to Tumor Progression.

Targeting Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) for Cancer Chemoprevention.

Peroxisome Proliferator-activated Receptor-D (PPARD) Coordinates Mouse Spermatogenesis by Modulating Extracellular Signal-regulated Kinase (ERK)-dependent Signaling.

Inhibition of testicular embryonal carcinoma cell tumorigenicity by peroxisome proliferator-activated receptor-β/δ- and retinoic acid receptor-dependent mechanisms.

Establishing the Role of PPARβ/δ in Carcinogenesis.

The Ron Receptor Tyrosine Kinase Regulates Macrophage Heterogeneity and Plays a Protective Role in Diet-Induced Obesity, Atherosclerosis, and Hepatosteatosis.

Editor's Highlight: Perfluorooctane Sulfonate-Choline Ion Pair Formation: A Potential Mechanism Modulating Hepatic Steatosis and Oxidative Stress in Mice.

Ligand activation of peroxisome proliferator-activated receptor-β/δ suppresses liver tumorigenesis in hepatitis B transgenic mice.

PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration.

Regulation of Cytochrome P450 2B10 (CYP2B10) Expression in Liver by Peroxisome Proliferator-activated Receptor-β/δ Modulation of SP1 Promoter Occupancy.

Omics Approaches To Probe Microbiota and Drug Metabolism Interactions.

Peroxisome proliferator-activated receptor-β/δ modulates mast cell phenotype.

Peroxisome proliferator-activated receptor-β/δ inhibits human neuroblastoma cell tumorigenesis by inducing p53- and SOX2-mediated cell differentiation.