Jeffrey M. Peters
Department of Veterinary and Biomedical Sciences
The Pennsylvania State University
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Hepatic regeneration in peroxisome proliferator-activated receptor alpha-null mice after partial hepatectomy.
Hepatology research : the official journal of the Japan Society of Hepatology Jan, 2002 | Pubmed ID: 11804834
Induction of CYP3A expression by dehydroepiandrosterone: involvement of the pregnane X receptor.
Drug metabolism and disposition: the biological fate of chemicals May, 2002 | Pubmed ID: 11950789
Targeted disruption of peroxisomal proliferator-activated receptor beta (delta) results in distinct gender differences in mouse brain phospholipid and esterified FA levels.
Lipids May, 2002 | Pubmed ID: 12056592
Effects of conjugated linoleic acid (CLA) on immune responses, body composition and stearoyl-CoA desaturase.
Canadian journal of applied physiology = Revue canadienne de physiologie appliquee Dec, 2002 | Pubmed ID: 12501000
Bezafibrate is a dual ligand for PPARalpha and PPARbeta: studies using null mice.
Biochimica et biophysica acta Jun, 2003 | Pubmed ID: 12782154
Comprehensive gene expression analysis of peroxisome proliferator-treated immortalized hepatocytes: identification of peroxisome proliferator-activated receptor alpha-dependent growth regulatory genes.
Cancer research Sep, 2003 | Pubmed ID: 14522898
PPARalpha agonist-induced rodent tumors: modes of action and human relevance.
Critical reviews in toxicology , 2003 | Pubmed ID: 14727734
Expression of base excision DNA repair genes is a sensitive biomarker for in vivo detection of chemical-induced chronic oxidative stress: identification of the molecular source of radicals responsible for DNA damage by peroxisome proliferators.
Cancer research Feb, 2004 | Pubmed ID: 14871837
Peroxisome proliferator-activated receptor beta/delta regulates very low density lipoprotein production and catabolism in mice on a Western diet.
The Journal of biological chemistry May, 2004 | Pubmed ID: 15001574
Peroxisome proliferator-activated receptor beta (delta)-dependent regulation of ubiquitin C expression contributes to attenuation of skin carcinogenesis.
The Journal of biological chemistry May, 2004 | Pubmed ID: 15033975
Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis.
Nature medicine May, 2004 | Pubmed ID: 15048110
PPARgamma influences susceptibility to DMBA-induced mammary, ovarian and skin carcinogenesis.
Carcinogenesis Sep, 2004 | Pubmed ID: 15073042
Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated receptor-alpha.
The Journal of biological chemistry Aug, 2004 | Pubmed ID: 15180999
PPARbeta/delta potentiates PPARgamma-stimulated adipocyte differentiation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Sep, 2004 | Pubmed ID: 15247146
Activation of mouse and human peroxisome proliferator-activated receptors (PPARs) by phthalate monoesters.
Toxicological sciences : an official journal of the Society of Toxicology Nov, 2004 | Pubmed ID: 15310864
The United States-Japan workshop on: The role of nuclear receptors in carcinogenesis.
Molecular carcinogenesis Oct, 2004 | Pubmed ID: 15378646
Peroxisome proliferator-activated receptor alpha protects against alcohol-induced liver damage.
Hepatology (Baltimore, Md.) Oct, 2004 | Pubmed ID: 15382117
Role of peroxisome proliferator-activated receptor-alpha (PPARalpha) in bezafibrate-induced hepatocarcinogenesis and cholestasis.
Carcinogenesis Jan, 2005 | Pubmed ID: 15447978
PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine.
Oncogene Nov, 2004 | Pubmed ID: 15480419
Regulation of human apoA-I by gemfibrozil and fenofibrate through selective peroxisome proliferator-activated receptor alpha modulation.
Arteriosclerosis, thrombosis, and vascular biology Mar, 2005 | Pubmed ID: 15618549
Peroxisome proliferator-activated receptor-beta/delta inhibits epidermal cell proliferation by down-regulation of kinase activity.
The Journal of biological chemistry Mar, 2005 | Pubmed ID: 15632134
Differences in cell proliferation in rodent and human hepatic derived cell lines exposed to ciprofibrate.
Cancer letters May, 2005 | Pubmed ID: 15863271
Peroxisome proliferator-activated receptor-alpha and liver cancer: where do we stand?
Journal of molecular medicine (Berlin, Germany) Oct, 2005 | Pubmed ID: 15976920
Protective effects of a peroxisome proliferator-activated receptor-beta/delta agonist in experimental autoimmune encephalomyelitis.
Journal of neuroimmunology Nov, 2005 | Pubmed ID: 16098614
The role of peroxisome proliferator-activated receptor-beta/delta in epithelial cell growth and differentiation.
Cellular signalling Jan, 2006 | Pubmed ID: 16109478
Evidence that ligand binding is a key determinant of Ah receptor-mediated transcriptional activity.
Archives of biochemistry and biophysics Oct, 2005 | Pubmed ID: 16137638
The aryl hydrocarbon receptor directly regulates expression of the potent mitogen epiregulin.
Toxicological sciences : an official journal of the Society of Toxicology Jan, 2006 | Pubmed ID: 16192470
The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR).
Toxicological sciences : an official journal of the Society of Toxicology Apr, 2006 | Pubmed ID: 16322072
Alterations in skin and stratified epithelia by constitutively activated PPARalpha.
The Journal of investigative dermatology Feb, 2006 | Pubmed ID: 16374467
Inhibition of chemically induced skin carcinogenesis by sulindac is independent of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta).
Carcinogenesis May, 2006 | Pubmed ID: 16418176
PPARdelta regulates glucose metabolism and insulin sensitivity.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2006 | Pubmed ID: 16492734
Ligand activation of peroxisome proliferator-activated receptor beta inhibits colon carcinogenesis.
Cancer research Apr, 2006 | Pubmed ID: 16618765
PPARdelta status and mismatch repair mediated neoplasia in the mouse intestine.
BMC cancer May, 2006 | Pubmed ID: 16672050
Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity.
Journal of lipid research Sep, 2006 | Pubmed ID: 16790840
Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver.
Critical reviews in toxicology May, 2006 | Pubmed ID: 16954067
Sustained formation of alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts in mouse liver by peroxisome proliferators is dependent upon peroxisome proliferator-activated receptor-alpha, but not NADPH oxidase.
Free radical biology & medicine Feb, 2007 | Pubmed ID: 17210446
Ligand activation of peroxisome proliferator-activated receptor-beta/delta(PPARbeta/delta) inhibits cell growth of human N/TERT-1 keratinocytes.
Cellular signalling Jun, 2007 | Pubmed ID: 17254750
PPARalpha and effects of TCE.
Environmental health perspectives Jan, 2007 | Pubmed ID: 17366801
The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta).
Free radical biology & medicine Apr, 2007 | Pubmed ID: 17382197
PPARbeta/delta protects against experimental colitis through a ligand-independent mechanism.
Digestive diseases and sciences Nov, 2007 | Pubmed ID: 17404849
Deregulation of tumor angiogenesis and blockade of tumor growth in PPARbeta-deficient mice.
The EMBO journal Aug, 2007 | Pubmed ID: 17641685
Transcriptional network governing the angiogenic switch in human pancreatic cancer.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2007 | Pubmed ID: 17652168
Growth of transgenic RAF-induced lung adenomas is increased in mice with a disrupted PPARbeta/delta gene.
International journal of oncology Sep, 2007 | Pubmed ID: 17671688
Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands do not potentiate growth of human cancer cell lines.
Carcinogenesis Dec, 2007 | Pubmed ID: 17693664
COX-2 suppresses tissue factor expression via endocannabinoid-directed PPARdelta activation.
The Journal of experimental medicine Sep, 2007 | Pubmed ID: 17724132
Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signaling mechanisms.
Carcinogenesis Jan, 2008 | Pubmed ID: 17893232
Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver.
The Journal of biological chemistry Dec, 2007 | Pubmed ID: 17962186
Peroxisome proliferator-activated receptor-beta/delta protects against chemically induced liver toxicity in mice.
Hepatology (Baltimore, Md.) Jan, 2008 | Pubmed ID: 18038451
Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands inhibit growth of UACC903 and MCF7 human cancer cell lines.
Toxicology Jan, 2008 | Pubmed ID: 18054822
Quantitative expression patterns of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) protein in mice.
Biochemical and biophysical research communications Jul, 2008 | Pubmed ID: 18442472
A Role for PPARbeta/delta in Tumor Stroma and Tumorigenesis.
PPAR research , 2008 | Pubmed ID: 18497874
Role of peroxisome-proliferator-activated receptor beta/delta (PPARbeta/delta) in gastrointestinal tract function and disease.
Clinical science (London, England : 1979) Aug, 2008 | Pubmed ID: 18616431
Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) attenuates carbon tetrachloride hepatotoxicity by downregulating proinflammatory gene expression.
Toxicological sciences : an official journal of the Society of Toxicology Oct, 2008 | Pubmed ID: 18622026
Ligand activation of peroxisome proliferator-activated receptor-beta/delta inhibits cell proliferation in human HaCaT keratinocytes.
Molecular pharmacology Nov, 2008 | Pubmed ID: 18687807
Peroxisome proliferator-activated receptor-delta agonist enhances vasculogenesis by regulating endothelial progenitor cells through genomic and nongenomic activations of the phosphatidylinositol 3-kinase/Akt pathway.
Circulation Sep, 2008 | Pubmed ID: 18711014
Nrf2- and PPAR alpha-mediated regulation of hepatic Mrp transporters after exposure to perfluorooctanoic acid and perfluorodecanoic acid.
Toxicological sciences : an official journal of the Society of Toxicology Dec, 2008 | Pubmed ID: 18757529
Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta) inhibits chemically induced skin tumorigenesis.
Carcinogenesis Dec, 2008 | Pubmed ID: 18799709
Effect of ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in human lung cancer cell lines.
Toxicology Dec, 2008 | Pubmed ID: 18950674
PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer.
Prostaglandins & other lipid mediators Apr, 2009 | Pubmed ID: 19101649
Regulation of peroxisome proliferator-activated receptor-alpha by MDM2.
Toxicological sciences : an official journal of the Society of Toxicology Mar, 2009 | Pubmed ID: 19103650
Regulation of peroxisome proliferator-activated receptors by e6-associated protein.
PPAR research , 2008 | Pubmed ID: 19107217
Differential hepatic effects of perfluorobutyrate mediated by mouse and human PPAR-alpha.
Toxicological sciences : an official journal of the Society of Toxicology Jul, 2009 | Pubmed ID: 19359353
Regulation of peroxisome proliferator-activated receptor-beta/delta by the APC/beta-CATENIN pathway and nonsteroidal antiinflammatory drugs.
Molecular carcinogenesis Oct, 2009 | Pubmed ID: 19415698
Sorting out the functional role(s) of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in cell proliferation and cancer.
Biochimica et biophysica acta Dec, 2009 | Pubmed ID: 19505534
Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) inhibits cell growth in a mouse mammary gland cancer cell line.
Cancer letters Feb, 2010 | Pubmed ID: 19660859
Ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase-2 enhances inhibition of skin tumorigenesis.
Toxicological sciences : an official journal of the Society of Toxicology Jan, 2010 | Pubmed ID: 19748995
Regulation of oligodendrocyte progenitor cell maturation by PPARδ: effects on bone morphogenetic proteins.
ASN neuro Jan, 2010 | Pubmed ID: 20001953
A natural propenoic acid derivative activates peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta).
Life sciences Mar, 2010 | Pubmed ID: 20153754
Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-beta/delta antagonist GSK3787.
Molecular pharmacology Sep, 2010 | Pubmed ID: 20516370
Synthesis of isosteric selenium analog of the PPARbeta/delta agonist GW501516 and comparison of biological activity.
Bioorganic & medicinal chemistry letters Jul, 2010 | Pubmed ID: 20542425
Effect of prenatal peroxisome proliferator-activated receptor alpha (PPARalpha) agonism on postnatal development.
Toxicology Sep, 2010 | Pubmed ID: 20637823
Xenobiotic metabolism, disposition, and regulation by receptors: from biochemical phenomenon to predictors of major toxicities.
Toxicological sciences : an official journal of the Society of Toxicology Mar, 2011 | Pubmed ID: 21059794
Chemoprevention of chemically induced skin tumorigenesis by ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase 2.
Molecular cancer therapeutics Dec, 2010 | Pubmed ID: 21159610
PPARβ/δ activation induces enteroendocrine L cell GLP-1 production.
Gastroenterology May, 2011 | Pubmed ID: 21300064
Functional characterization of peroxisome proliferator-activated receptor-β/δ expression in colon cancer.
Molecular carcinogenesis Nov, 2011 | Pubmed ID: 21400612
Stable over-expression of PPARβ/δ and PPARγ to examine receptor signaling in human HaCaT keratinocytes.
Cellular signalling Dec, 2011 | Pubmed ID: 21843636
PPAR action in insulin resistance unraveled by metabolomics: potential clinical implications.
Genome medicine Aug, 2011 | Pubmed ID: 21861850
Why toxic equivalency factors are not suitable for perfluoroalkyl chemicals.
Chemical research in toxicology Oct, 2011 | Pubmed ID: 21913657
Immunomodulatory action of dietary fish oil and targeted deletion of intestinal epithelial cell PPARδ in inflammation-induced colon carcinogenesis.
American journal of physiology. Gastrointestinal and liver physiology Jan, 2012 | Pubmed ID: 21940900
NTP-CERHR expert panel report on the developmental toxicity of soy infant formula.
Birth defects research. Part B, Developmental and reproductive toxicology Oct, 2011 | Pubmed ID: 21948615
Dissecting the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) in colon, breast, and lung carcinogenesis.
Cancer metastasis reviews Dec, 2011 | Pubmed ID: 22037942
The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention.
Nature reviews. Cancer Mar, 2012 | Pubmed ID: 22318237
Peroxisome proliferator-activated receptor β/δ cross talks with E2F and attenuates mitosis in HRAS-expressing cells.
Molecular and cellular biology Jun, 2012 | Pubmed ID: 22473992
Modulation of gastrointestinal inflammation and colorectal tumorigenesis by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ).
Drug discovery today. Disease mechanisms , 2011 | Pubmed ID: 22611424
A species difference in the peroxisome proliferator-activated receptor α-dependent response to the developmental effects of perfluorooctanoic acid.
Toxicological sciences : an official journal of the Society of Toxicology Feb, 2013 | Pubmed ID: 23143925
Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4.
BMC genomics , 2012 | Pubmed ID: 23176727
Metabolomics: an essential tool to understand the function of peroxisome proliferator-activated receptor alpha.
Toxicologic pathology Feb, 2013 | Pubmed ID: 23197196
Cholestasis induces reversible accumulation of periplakin in mouse liver.
BMC gastroenterology Jul, 2013 | Pubmed ID: 23849208
PPARβ/δ modulates ethanol-induced hepatic effects by decreasing pyridoxal kinase activity.
Toxicology Sep, 2013 | Pubmed ID: 23851158
Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study.
Critical reviews in toxicology Jan, 2014 | Pubmed ID: 24180432
Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis.
The Journal of pharmacology and experimental therapeutics Feb, 2014 | Pubmed ID: 24309559
Targeting estrogen receptor-β for the prevention of nonmelanoma skin cancer.
Cancer prevention research (Philadelphia, Pa.) Feb, 2014 | Pubmed ID: 24464730
Activation of peroxisome proliferator-activated receptor-β/δ (PPAR-β/δ) inhibits human breast cancer cell line tumorigenicity.
Molecular cancer therapeutics Apr, 2014 | Pubmed ID: 24464939
Modulation of aryl hydrocarbon receptor (AHR)-dependent signaling by peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in keratinocytes.
Carcinogenesis Jul, 2014 | Pubmed ID: 24639079
The nuclear receptor peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) promotes oncogene-induced cellular senescence through repression of endoplasmic reticulum stress.
The Journal of biological chemistry Jul, 2014 | Pubmed ID: 24898257
Comparative in vivo and in vitro analysis of possible estrogenic effects of perfluorooctanoic acid.
Toxicology Dec, 2014 | Pubmed ID: 25456267
M-CSF from Cancer Cells Induces Fatty Acid Synthase and PPARβ/δ Activation in Tumor Myeloid Cells, Leading to Tumor Progression.
Cell reports Mar, 2015 | Pubmed ID: 25753425
Targeting Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) for Cancer Chemoprevention.
Current pharmacology reports , 2015 | Pubmed ID: 26000234
Peroxisome Proliferator-activated Receptor-D (PPARD) Coordinates Mouse Spermatogenesis by Modulating Extracellular Signal-regulated Kinase (ERK)-dependent Signaling.
The Journal of biological chemistry Sep, 2015 | Pubmed ID: 26242735
Inhibition of testicular embryonal carcinoma cell tumorigenicity by peroxisome proliferator-activated receptor-β/δ- and retinoic acid receptor-dependent mechanisms.
Oncotarget Nov, 2015 | Pubmed ID: 26431381
Establishing the Role of PPARβ/δ in Carcinogenesis.
Trends in endocrinology and metabolism: TEM Nov, 2015 | Pubmed ID: 26490384
The Ron Receptor Tyrosine Kinase Regulates Macrophage Heterogeneity and Plays a Protective Role in Diet-Induced Obesity, Atherosclerosis, and Hepatosteatosis.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2016 | Pubmed ID: 27233965
Editor's Highlight: Perfluorooctane Sulfonate-Choline Ion Pair Formation: A Potential Mechanism Modulating Hepatic Steatosis and Oxidative Stress in Mice.
Toxicological sciences : an official journal of the Society of Toxicology Sep, 2016 | Pubmed ID: 27413108
Ligand activation of peroxisome proliferator-activated receptor-β/δ suppresses liver tumorigenesis in hepatitis B transgenic mice.
Toxicology Jul, 2016 | Pubmed ID: 27427494
PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration.
Aging Sep, 2016 | Pubmed ID: 27622388
Regulation of Cytochrome P450 2B10 (CYP2B10) Expression in Liver by Peroxisome Proliferator-activated Receptor-β/δ Modulation of SP1 Promoter Occupancy.
The Journal of biological chemistry Nov, 2016 | Pubmed ID: 27765815
Omics Approaches To Probe Microbiota and Drug Metabolism Interactions.
Chemical research in toxicology Dec, 2016 | Pubmed ID: 27782392
Peroxisome proliferator-activated receptor-β/δ modulates mast cell phenotype.
Immunology Apr, 2017 | Pubmed ID: 27935639
Peroxisome proliferator-activated receptor-β/δ inhibits human neuroblastoma cell tumorigenesis by inducing p53- and SOX2-mediated cell differentiation.
Molecular carcinogenesis Dec, 2016 | Pubmed ID: 27996177
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