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Department of Chemical Engineering
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Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism.
Clinical cancer research : an official journal of the American Association for Cancer Research Apr, 2002 | Pubmed ID: 11948144
Sparse initial entrapment of systemically injected Salmonella typhimurium leads to heterogeneous accumulation within tumors.
Cancer research Sep, 2003 | Pubmed ID: 14500342
Glutathione-mediated delivery and release using monolayer protected nanoparticle carriers.
Journal of the American Chemical Society Feb, 2006 | Pubmed ID: 16433515
Salmonella typhimurium specifically chemotax and proliferate in heterogeneous tumor tissue in vitro.
Biotechnology and bioengineering Jul, 2006 | Pubmed ID: 16470601
Light-regulated release of DNA and its delivery to nuclei by means of photolabile gold nanoparticles.
Angewandte Chemie (International ed. in English) May, 2006 | Pubmed ID: 16572498
Incorporating energy metabolism into a growth model of multicellular tumor spheroids.
Journal of theoretical biology Sep, 2006 | Pubmed ID: 16650438
Estradiol stimulates the biosynthetic pathways of breast cancer cells: detection by metabolic flux analysis.
Metabolic engineering Nov, 2006 | Pubmed ID: 16904360
Flux analysis shows that hypoxia-inducible-factor-1-alpha minimally affects intracellular metabolism in tumor spheroids.
Biotechnology and bioengineering Apr, 2007 | Pubmed ID: 17009333
Profile of a bacterial tumor killer.
Nature biotechnology Dec, 2006 | Pubmed ID: 17160044
Salmonella typhimurium lacking ribose chemoreceptors localize in tumor quiescence and induce apoptosis.
Cancer research Apr, 2007 | Pubmed ID: 17409428
Integrating cell-cycle progression, drug penetration and energy metabolism to identify improved cancer therapeutic strategies.
Journal of theoretical biology Jul, 2008 | Pubmed ID: 18402980
Bacterial therapies: completing the cancer treatment toolbox.
Current opinion in biotechnology Oct, 2008 | Pubmed ID: 18760353
Single-cell analysis demonstrates how nutrient deprivation creates apoptotic and quiescent cell populations in tumor cylindroids.
Biotechnology and bioengineering Nov, 2008 | Pubmed ID: 18814293
A multipurpose microfluidic device designed to mimic microenvironment gradients and develop targeted cancer therapeutics.
Lab on a chip Feb, 2009 | Pubmed ID: 19190790
Efficient gene delivery vectors by tuning the surface charge density of amino acid-functionalized gold nanoparticles.
ACS nano Nov, 2008 | Pubmed ID: 19206385
Active and inactive metabolic pathways in tumor spheroids: determination by GC-MS.
Biotechnology progress May-Jun, 2010 | Pubmed ID: 20014107
Tuning payload delivery in tumour cylindroids using gold nanoparticles.
Nature nanotechnology Jun, 2010 | Pubmed ID: 20383126
Engineering the perfect (bacterial) cancer therapy.
Nature reviews. Cancer Nov, 2010 | Pubmed ID: 20944664
Motility is critical for effective distribution and accumulation of bacteria in tumor tissue.
Integrative biology : quantitative biosciences from nano to macro Feb, 2012 | Pubmed ID: 22193245
Micrometer-scale oxygen delivery rearranges cells and prevents necrosis in tumor tissue in vitro.
Biotechnology progress Dec, 2011 | Pubmed ID: 22228537
University Of Massachusetts Amherst
Bhushan J. Toley*,1,
Dan E. Ganz*,1,
Colin L. Walsh1,
Neil S. Forbes1
1Department of Chemical Engineering, University Of Massachusetts Amherst
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