Maria Luisa Mangoni

Effect of natural L- to D-amino acid conversion on the organization, membrane binding, and biological function of the antimicrobial peptides bombinins H.

Temporins, anti-infective peptides with expanding properties.

Biological characterization and modes of action of temporins and bombinins H, multiple forms of short and mildly cationic anti-microbial peptides from amphibian skin.

Lipopolysaccharide, a key molecule involved in the synergism between temporins in inhibiting bacterial growth and in endotoxin neutralization.

Temporins and their synergism against Gram-negative bacteria and in lipopolysaccharide detoxification.

Short native antimicrobial peptides and engineered ultrashort lipopeptides: similarities and differences in cell specificities and modes of action.

Host-defense peptides: from biology to therapeutic strategies.

A lesson from Bombinins H, mildly cationic diastereomeric antimicrobial peptides from Bombina skin.

Esculentin-1a(1-21)NH2: a frog skin-derived peptide for microbial keratitis.

Synergistic fungicidal activity of the lipopeptide bacillomycin D with amphotericin B against pathogenic Candida species.

Fighting microbial infections: A lesson from amphibian skin-derived esculentin-1 peptides.

The Frog Skin-Derived Antimicrobial Peptide Esculentin-1a(1-21)NH2 Promotes the Migration of Human HaCaT Keratinocytes in an EGF Receptor-Dependent Manner: A Novel Promoter of Human Skin Wound Healing?

Naturally Occurring Peptides from Rana temporaria: Antimicrobial Properties and More.

D-Amino acids incorporation in the frog skin-derived peptide esculentin-1a(1-21)NH2 is beneficial for its multiple functions.

Overcoming barriers in Pseudomonas aeruginosa lung infections: Engineered nanoparticles for local delivery of a cationic antimicrobial peptide.

Editorial: Antimicrobial Peptides in Medicinal Chemistry: Advances and Applications.

Conformational Analysis of the Host-Defense Peptides Pseudhymenochirin-1Pb and -2Pa and Design of Analogues with Insulin-Releasing Activities and Reduced Toxicities.

NMR structure and binding of esculentin-1a (1-21)NH2 and its diastereomer to lipopolysaccharide: Correlation with biological functions.

Antimicrobial peptides and wound healing: biological and therapeutic considerations.

Purification, Conformational Analysis, and Properties of a Family of Tigerinin Peptides from Skin Secretions of the Crowned Bullfrog Hoplobatrachus occipitalis.

Esculentin-1a-Derived Peptides Promote Clearance of Pseudomonas aeruginosa Internalized in Bronchial Cells of Cystic Fibrosis Patients and Lung Cell Migration: Biochemical Properties and a Plausible Mode of Action.

Gold-nanoparticles coated with the antimicrobial peptide esculentin-1a(1-21)NHas a reliable strategy for antipseudomonal drugs.

Effects of Aib residues insertion on the structural-functional properties of the frog skin-derived peptide esculentin-1a(1-21)NH.

Cell-Density Dependence of Host-Defense Peptide Activity and Selectivity in the Presence of Host Cells.

Methods for In Vitro Analysis of Antimicrobial Activity and Toxicity of Anti-keratitis Peptides: Bacterial Viability in Tears, MTT, and TNF-α Release Assays.

Methods for In Vivo/Ex Vivo Analysis of Antimicrobial Peptides in Bacterial Keratitis: siRNA Knockdown, Colony Counts, Myeloperoxidase, Immunostaining, and RT-PCR Assays.

Cytotoxic peptides with insulin-releasing activities from skin secretions of the Italian stream frog Rana italica (Ranidae).

In vivo therapeutic efficacy of frog skin-derived peptides against Pseudomonas aeruginosa-induced pulmonary infection.

Glycine-replaced derivatives of [Pro,DLeu]TL, a temporin L analogue: Evaluation of antimicrobial, cytotoxic and hemolytic activities.

Membrane perturbing activities and structural properties of the frog-skin derived peptide Esculentin-1a(1-21)NHand its Diastereomer Esc(1-21)-1c: Correlation with their antipseudomonal and cytotoxic activity.

Peptidomic analysis of skin secretions of the Mexican burrowing toad Rhinophrynus dorsalis (Rhinophrynidae): Insight into the origin of host-defense peptides within the Pipidae and characterization of a proline-arginine-rich peptide.

Esculentin-1a derived peptides kill Pseudomonas aeruginosa biofilm on soft contact lenses and retain antibacterial activity upon immobilization to the lens surface.

Assessment of the potential of temporin peptides from the frog Rana temporaria (Ranidae) as anti-diabetic agents.