Michelle L. James

Preclinical evaluation of Raman nanoparticle biodistribution for their potential use in clinical endoscopy imaging.

A molecular imaging primer: modalities, imaging agents, and applications.

New Positron Emission Tomography (PET) Radioligand for Imaging σ-1 Receptors in Living Subjects.

Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

PET imaging of stroke-induced neuroinflammation in mice using [18F]PBR06.

Integrin-targeted molecular imaging of experimental abdominal aortic aneurysms by (18)F-labeled Arg-Gly-Asp positron-emission tomography.

A 18F-labeled saxitoxin derivative for in vivo PET-MR imaging of voltage-gated sodium channel expression following nerve injury.

Evaluation of σ-1 receptor radioligand 18F-FTC-146 in rats and squirrel monkeys using PET.

Antiviral drug ganciclovir is a potent inhibitor of microglial proliferation and neuroinflammation.

PET imaging of translocator protein (18 kDa) in a mouse model of Alzheimer's disease using N-(2,5-dimethoxybenzyl)-2-18F-fluoro-N-(2-phenoxyphenyl)acetamide.

Further validation to support clinical translation of [(18)F]FTC-146 for imaging sigma-1 receptors.

Microglial malfunction: the third rail in the development of Alzheimer's disease.

PET imaging of tumor glycolysis downstream of hexokinase through noninvasive measurement of pyruvate kinase M2.

Development of [F]DASA-23 for Imaging Tumor Glycolysis Through Noninvasive Measurement of Pyruvate Kinase M2.

Human umbilical cord plasma proteins revitalize hippocampal function in aged mice.

Multimodal assessment of SERS nanoparticle biodistribution post ingestion reveals new potential for clinical translation of Raman imaging.

[F]GE-180 PET Detects Reduced Microglia Activation After LM11A-31 Therapy in a Mouse Model of Alzheimer's Disease.

Imaging B Cells in a Mouse Model of Multiple Sclerosis Using Cu-Rituximab PET.

Visualizing Nerve Injury in a Neuropathic Pain Model with [F]FTC-146 PET/MRI.

[F]FSPG-PET reveals increased cystine/glutamate antiporter (xc-) activity in a mouse model of multiple sclerosis.

Imaging activated T cells predicts response to cancer vaccines.

TSPO-PET Imaging Using [18F]PBR06 is a Potential Translatable Biomarker for Treatment Response in Huntington's Disease: Preclinical Evidence with the p75NTR Ligand LM11A-31.

C-DPA-713 Versus F-GE-180: A Preclinical Comparison of Translocator Protein 18 kDa PET Tracers to Visualize Acute and Chronic Neuroinflammation in a Mouse Model of Ischemic Stroke.

Successful treatment of chronic knee pain following localization by a sigma-1 receptor radioligand and PET/MRI: a case report.

Microglial Modulation as a Target for Chronic Pain: From the Bench to the Bedside and Back.

Longitudinal translocator protein-18 kDa-positron emission tomography imaging of peripheral and central myeloid cells in a mouse model of complex regional pain syndrome.

Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity.

Demarcation of Sepsis-Induced Peripheral and Central Acidosis with pH (Low) Insertion Cycle Peptide.

Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation.

Physiological blood-brain transport is impaired with age by a shift in transcytosis.

Neuroinflammation PET Imaging: Current Opinion and Future Directions.

Training the next generation of radiopharmaceutical scientists.

Simultaneous FDG-PET/MRI detects hippocampal subfield metabolic differences in AD/MCI.

Histologic evaluation of activation of acute inflammatory response in a mouse model following ultrasound-mediated blood-brain barrier using different acoustic pressures and microbubble doses.

Development of a CD19 PET tracer for detecting B cells in a mouse model of multiple sclerosis.

On the consensus nomenclature rules for radiopharmaceutical chemistry - Reconsideration of radiochemical conversion.

Hippocampal subfield imaging and fractional anisotropy show parallel changes in Alzheimer's disease tau progression using simultaneous tau-PET/MRI at 3T.

A Clinical PET Imaging Tracer ([F]DASA-23) to Monitor Pyruvate Kinase M2-Induced Glycolytic Reprogramming in Glioblastoma.

Whole-body PET Imaging of T-cell Response to Glioblastoma.

Tracking Innate Immune Activation in a Mouse Model of Parkinson's Disease Using TREM1 and TSPO PET Tracers.

Approaches for Addressing Challenges in CNS Radiopharmaceutical Design.

Radiosynthesis and initial preclinical evaluation of [C]AZD1283 as a potential P2Y12R PET radiotracer.

ICOS immunoPET enables visualization of activated T cells and early diagnosis of murine acute gastrointestinal GvHD.

Multimodal imaging of capsid and cargo reveals differential brain targeting and liver detargeting of systemically-administered AAVs.