Giuseppe Pantaleo

Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases.

Long sequence duplications, repeats, and palindromes in HIV-1 gp120: length variation in V4 as the product of misalignment mechanism.

Poxvirus vector-based HIV vaccines.

Modulation of human memory T-cell function by different antigen-presenting cells.

The number of Toll-like receptor 9-agonist motifs in the adenovirus genome correlates with induction of dendritic cell maturation by adenovirus immune complexes.

A Novel HIV Vaccine Adjuvanted by IC31 Induces Robust and Persistent Humoral and Cellular Immunity.

NYVAC immunization induces polyfunctional HIV-specific T-cell responses in chronically-infected, ART-treated HIV patients.

Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production.

Inadequate T follicular cell help impairs B cell immunity during HIV infection.

Vaccine and immunotherapeutic interventions.

Rapid perturbation in viremia levels drives increases in functional avidity of HIV-specific CD8 T cells.

Safety and efficacy of the peptide-based therapeutic vaccine for HIV-1, Vacc-4x: a phase 2 randomised, double-blind, placebo-controlled trial.

The immune space: a concept and template for rationalizing vaccine development.

Immune activation alters cellular and humoral responses to yellow fever 17D vaccine.

Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders.

Combined use of Mycobacterium tuberculosis-specific CD4 and CD8 T-cell responses is a powerful diagnostic tool of active tuberculosis.

The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo.

Immune correlates of vaccine protection against HIV-1 acquisition.

A case for preART-adjusted endpoints in HIV therapeutic vaccine trials.

Clinically-relevant threshold of preformed donor-specific anti-HLA antibodies in kidney transplantation.

PD-1(+) and follicular helper T cells are responsible for persistent HIV-1 transcription in treated aviremic individuals.

Therapeutic vaccines and immunological intervention in HIV infection: a paradigm change.

Follicular CD8 T cells accumulate in HIV infection and can kill infected cells in vitro via bispecific antibodies.

B-cell abnormalities and impact on antibody response in HIV infection.

Mixed Th1 and Th2 Mycobacterium tuberculosis-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania.

Targeted Immune Interventions for an HIV-1 Cure.

Cell-Mediated Immune Predictors of Vaccine Effect on Viral Load and CD4 Count in a Phase 2 Therapeutic HIV-1 Vaccine Clinical Trial.

HIV-1 Envelope Glycoproteins from Diverse Clades Differentiate Antibody Responses and Durability among Vaccinees.

Immunogenicity of NYVAC Prime-Protein Boost Human Immunodeficiency Virus Type 1 Envelope Vaccination and Simian-Human Immunodeficiency Virus Challenge of Nonhuman Primates.

Hyperglycaemia is inversely correlated with live M. bovis BCG-specific CD4 T cell responses in Tanzanian adults with latent or active tuberculosis.

CD32 and PD-1 Lymph Node CD4 T Cells Support Persistent HIV-1 Transcription in Treated Aviremic Individuals.

TLR3 agonist and CD40-targeting vaccination induces immune responses and reduces HIV-1 reservoirs.

Immunogenicity and safety of double versus standard dose of the seasonal influenza vaccine in solid-organ transplant recipients: A randomized controlled trial.

Comparative analysis and generation of a robust HIV-1 DNA quantification assay.

Antibodies to and reproductive health issues in women with SLE: a case-control study.

HIV Infection Functionally Impairs Mycobacterium tuberculosis-Specific CD4 and CD8 T-Cell Responses.

Re-boost immunizations with the peptide-based therapeutic HIV vaccine, Vacc-4x, restores geometric mean viral load set-point during treatment interruption.

Detection of antisense protein (ASP) RNA transcripts in individuals infected with human immunodeficiency virus type 1 (HIV-1).

Multi-arm, multi-stage randomised controlled trials for evaluating therapeutic HIV cure interventions.

Tumor suppression of novel anti-PD-1 antibodies mediated through CD28 costimulatory pathway.

Lymph node migratory dendritic cells modulate HIV-1 transcription through PD-1 engagement.

Safety and tolerance of lymph node biopsies from chronic HIV-1 volunteers in rural Tanzania.

DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial.

Safety and immunogenicity of a multivalent HIV vaccine comprising envelope protein with either DNA or NYVAC vectors (HVTN 096): a phase 1b, double-blind, placebo-controlled trial.

Development of a novel human phage display-derived anti-LAG3 scFv antibody targeting CD8 T lymphocyte exhaustion.

Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.

Antigenic competition in CD4 T cell responses in a randomized, multicenter, double-blind clinical HIV vaccine trial.