Division of Immunology and Allergy
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Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases.
Nature reviews. Immunology May, 2006 | Pubmed ID: 16622477
Long sequence duplications, repeats, and palindromes in HIV-1 gp120: length variation in V4 as the product of misalignment mechanism.
Virology Mar, 2010 | Pubmed ID: 20106497
Poxvirus vector-based HIV vaccines.
Current opinion in HIV and AIDS Sep, 2010 | Pubmed ID: 20978379
Modulation of human memory T-cell function by different antigen-presenting cells.
European journal of immunology Mar, 2012 | Pubmed ID: 22144294
The number of Toll-like receptor 9-agonist motifs in the adenovirus genome correlates with induction of dendritic cell maturation by adenovirus immune complexes.
Journal of virology Jun, 2012 | Pubmed ID: 22491454
A Novel HIV Vaccine Adjuvanted by IC31 Induces Robust and Persistent Humoral and Cellular Immunity.
PloS one , 2012 | Pubmed ID: 22848738
NYVAC immunization induces polyfunctional HIV-specific T-cell responses in chronically-infected, ART-treated HIV patients.
European journal of immunology Nov, 2012 | Pubmed ID: 22930439
Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production.
The Journal of experimental medicine Jan, 2013 | Pubmed ID: 23254284
Inadequate T follicular cell help impairs B cell immunity during HIV infection.
Nature medicine Apr, 2013 | Pubmed ID: 23475201
Vaccine and immunotherapeutic interventions.
Current opinion in HIV and AIDS May, 2013 | Pubmed ID: 23478912
Rapid perturbation in viremia levels drives increases in functional avidity of HIV-specific CD8 T cells.
PLoS pathogens , 2013 | Pubmed ID: 23853580
Safety and efficacy of the peptide-based therapeutic vaccine for HIV-1, Vacc-4x: a phase 2 randomised, double-blind, placebo-controlled trial.
The Lancet. Infectious diseases Apr, 2014 | Pubmed ID: 24525316
The immune space: a concept and template for rationalizing vaccine development.
AIDS research and human retroviruses Nov, 2014 | Pubmed ID: 24857015
Immune activation alters cellular and humoral responses to yellow fever 17D vaccine.
The Journal of clinical investigation Jul, 2014 | Pubmed ID: 24911151
Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders.
The Journal of experimental medicine Sep, 2014 | Pubmed ID: 25225461
Combined use of Mycobacterium tuberculosis-specific CD4 and CD8 T-cell responses is a powerful diagnostic tool of active tuberculosis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Feb, 2015 | Pubmed ID: 25362202
The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo.
PLoS pathogens Sep, 2015 | Pubmed ID: 26379282
Immune correlates of vaccine protection against HIV-1 acquisition.
Science translational medicine Oct, 2015 | Pubmed ID: 26491081
A case for preART-adjusted endpoints in HIV therapeutic vaccine trials.
Vaccine Mar, 2016 | Pubmed ID: 26826543
Clinically-relevant threshold of preformed donor-specific anti-HLA antibodies in kidney transplantation.
Human immunology Jun, 2016 | Pubmed ID: 27085791
PD-1(+) and follicular helper T cells are responsible for persistent HIV-1 transcription in treated aviremic individuals.
Nature medicine 07, 2016 | Pubmed ID: 27239760
Therapeutic vaccines and immunological intervention in HIV infection: a paradigm change.
Current opinion in HIV and AIDS 11, 2016 | Pubmed ID: 27607591
Follicular CD8 T cells accumulate in HIV infection and can kill infected cells in vitro via bispecific antibodies.
Science translational medicine 01, 2017 | Pubmed ID: 28100833
B-cell abnormalities and impact on antibody response in HIV infection.
Current opinion in HIV and AIDS May, 2017 | Pubmed ID: 28422784
Mixed Th1 and Th2 Mycobacterium tuberculosis-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania.
PLoS neglected tropical diseases Jul, 2017 | Pubmed ID: 28759590
Targeted Immune Interventions for an HIV-1 Cure.
Trends in molecular medicine 10, 2017 | Pubmed ID: 28890135
Cell-Mediated Immune Predictors of Vaccine Effect on Viral Load and CD4 Count in a Phase 2 Therapeutic HIV-1 Vaccine Clinical Trial.
EBioMedicine Oct, 2017 | Pubmed ID: 28970080
HIV-1 Envelope Glycoproteins from Diverse Clades Differentiate Antibody Responses and Durability among Vaccinees.
Journal of virology 04, 2018 | Pubmed ID: 29386288
Immunogenicity of NYVAC Prime-Protein Boost Human Immunodeficiency Virus Type 1 Envelope Vaccination and Simian-Human Immunodeficiency Virus Challenge of Nonhuman Primates.
Journal of virology 04, 2018 | Pubmed ID: 29437967
Hyperglycaemia is inversely correlated with live M. bovis BCG-specific CD4 T cell responses in Tanzanian adults with latent or active tuberculosis.
Immunity, inflammation and disease 06, 2018 | Pubmed ID: 29642283
CD32 and PD-1 Lymph Node CD4 T Cells Support Persistent HIV-1 Transcription in Treated Aviremic Individuals.
Journal of virology 10, 2018 | Pubmed ID: 29976671
TLR3 agonist and CD40-targeting vaccination induces immune responses and reduces HIV-1 reservoirs.
The Journal of clinical investigation 10, 2018 | Pubmed ID: 30148455
Immunogenicity and safety of double versus standard dose of the seasonal influenza vaccine in solid-organ transplant recipients: A randomized controlled trial.
Vaccine 10, 2018 | Pubmed ID: 30181045
Comparative analysis and generation of a robust HIV-1 DNA quantification assay.
Journal of virological methods 01, 2019 | Pubmed ID: 30326210
Antibodies to and reproductive health issues in women with SLE: a case-control study.
Lupus science & medicine , 2018 | Pubmed ID: 30538819
HIV Infection Functionally Impairs Mycobacterium tuberculosis-Specific CD4 and CD8 T-Cell Responses.
Journal of virology 03, 2019 | Pubmed ID: 30541853
Re-boost immunizations with the peptide-based therapeutic HIV vaccine, Vacc-4x, restores geometric mean viral load set-point during treatment interruption.
PloS one , 2019 | Pubmed ID: 30699178
Detection of antisense protein (ASP) RNA transcripts in individuals infected with human immunodeficiency virus type 1 (HIV-1).
The Journal of general virology May, 2019 | Pubmed ID: 30896385
Multi-arm, multi-stage randomised controlled trials for evaluating therapeutic HIV cure interventions.
The lancet. HIV May, 2019 | Pubmed ID: 31047670
Tumor suppression of novel anti-PD-1 antibodies mediated through CD28 costimulatory pathway.
The Journal of experimental medicine Jul, 2019 | Pubmed ID: 31123083
Lymph node migratory dendritic cells modulate HIV-1 transcription through PD-1 engagement.
PLoS pathogens Jul, 2019 | Pubmed ID: 31329640
Safety and tolerance of lymph node biopsies from chronic HIV-1 volunteers in rural Tanzania.
BMC research notes Sep, 2019 | Pubmed ID: 31492170
DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial.
The Journal of clinical investigation Nov, 2019 | Pubmed ID: 31566579
Safety and immunogenicity of a multivalent HIV vaccine comprising envelope protein with either DNA or NYVAC vectors (HVTN 096): a phase 1b, double-blind, placebo-controlled trial.
The lancet. HIV Nov, 2019 | Pubmed ID: 31601541
Development of a novel human phage display-derived anti-LAG3 scFv antibody targeting CD8 T lymphocyte exhaustion.
BMC biotechnology 10, 2019 | Pubmed ID: 31623599
Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.
Cell host & microbe 11, 2019 | Pubmed ID: 31653484
Antigenic competition in CD4 T cell responses in a randomized, multicenter, double-blind clinical HIV vaccine trial.
Science translational medicine Nov, 2019 | Pubmed ID: 31748227
Antonio Mancarella1,
Francesco A. Procopio1,
Tilmann Achsel2,
Elisa De Crignis3,
Brian T. Foley4,
Giampietro Corradin5,
Claudia Bagni2,
Giuseppe Pantaleo1,
Cecilia Graziosi1
1Division of Immunology and Allergy, Lausanne University Hospital,
2Department of Fundamental Neuroscience, University of Lausanne,
3Department of Biochemistry, Erasmus Medical Center,
4Theoretical Biology and Biophysics Group, Los Alamos National Laboratories,
5Department of Biochemistry, University of Lausanne
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