Ralph P. Mason

Differential oxygen dynamics in two diverse Dunning prostate R3327 rat tumor sublines (MAT-Lu and HI) with respect to growth and respiratory challenge.

Interplay of tumor vascular oxygenation and tumor pO2 observed using near-infrared spectroscopy, an oxygen needle electrode, and 19F MR pO2 mapping.

Quantitative assessment of tumor oxygen dynamics: molecular imaging for prognostic radiology.

Dynamic breast tumor oximetry: the development of prognostic radiology.

Correlation of tumor oxygen dynamics with radiation response of the dunning prostate R3327-HI tumor.

Dynamic response of breast tumor oxygenation to hyperoxic respiratory challenge monitored with three oxygen-sensitive parameters.

Tumor oxygen dynamics: correlation of in vivo MRI with histological findings.

Molecular imaging in prostate cancer.

Tumor oximetry: comparison of 19F MR EPI and electrodes.

Oxygenation in a human tumor xenograft: manipulation through respiratory challenge and antibody-directed infarction.

Tumor oxygen dynamics: comparison of 19F MR EPI and frequency domain NIR spectroscopy.

Biodistribution of phosphodiester and phosphorothioate siRNA.

Novel NMR approach to assessing gene transfection: 4-fluoro-2-nitrophenyl-beta-D-galactopyranoside as a prototype reporter molecule for beta-galactosidase.

Near-infrared spectroscopy and imaging of tumor vascular oxygenation.

Measuring changes in tumor oxygenation.

Comparison of BOLD contrast and Gd-DTPA dynamic contrast-enhanced imaging in rat prostate tumor.

Validating bioluminescence imaging as a high-throughput, quantitative modality for assessing tumor burden.

Novel NMR platform for detecting gene transfection: synthesis and evaluation of fluorinated phenyl beta-D-galactosides with potential application for assessing LacZ gene expression.

19F: a versatile reporter for non-invasive physiology and pharmacology using magnetic resonance.

Tumor physiologic response to combretastatin A4 phosphate assessed by MRI.

Continuous low-dose (metronomic) chemotherapy on rat prostate tumors evaluated using MRI in vivo and comparison with histology.

Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma.

Synthesis and evaluation of novel enhanced gene reporter molecules: detection of beta-galactosidase activity using 19F NMR of trifluoromethylated aryl beta-D-galactopyranosides.

Tumour oxygen dynamics measured simultaneously by near-infrared spectroscopy and 19F magnetic resonance imaging in rats.

Novel 1H NMR approach to quantitative tissue oximetry using hexamethyldisiloxane.

Synthesis and characterization of novel lacZ gene reporter molecules: detection of beta-galactosidase activity by 19F nuclear magnetic resonance of polyglycosylated fluorinated vitamin B6.

Prevention of thiazide-induced hypokalemia without magnesium depletion by potassium-magnesium-citrate.

Synthesis and evaluation of a novel gene reporter molecule: detection of beta-galactosidase activity using 19F NMR of a fluorinated vitamin B6 conjugate+.

Imaging beta-galactosidase activity using 19F chemical shift imaging of LacZ gene-reporter molecule 2-fluoro-4-nitrophenol-beta-D-galactopyranoside.

Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy.

The use of histone deacetylase inhibitor FK228 and DNA hypomethylation agent 5-azacytidine in human bladder cancer therapy.

Correlation of radiation response with tumor oxygenation in the Dunning prostate R3327-AT1 tumor.

19F-NMR detection of lacZ gene expression via the enzymic hydrolysis of 2-fluoro-4-nitrophenyl beta-D-galactopyranoside in vivo in PC3 prostate tumor xenografts in the mouse.

Physical principles of quantitative nuclear magnetic resonance oximetry.

Antivascular effects of combretastatin A4 phosphate in breast cancer xenograft assessed using dynamic bioluminescence imaging and confirmed by MRI.

A 19F-NMR approach using reporter molecule pairs to assess beta-galactosidase in human xenograft tumors in vivo.

Vascular imaging of solid tumors in rats with a radioactive arsenic-labeled antibody that binds exposed phosphatidylserine.

Pten haploinsufficiency accelerates formation of high-grade astrocytomas.

Evaluation of red CdTe and near infrared CdHgTe quantum dots by fluorescent imaging.

Exploring feasibility of multicolored CdTe quantum dots for in vitro and in vivo fluorescent imaging.

Molecular imaging of hypoxia.

Proton imaging of siloxanes to map tissue oxygenation levels (PISTOL): a tool for quantitative tissue oximetry.

Development of aliphatic biodegradable photoluminescent polymers.

Comparison of 1H blood oxygen level-dependent (BOLD) and 19F MRI to investigate tumor oxygenation.

High-throughput quantitative bioluminescence imaging for assessing tumor burden.

In vitro and In vivo Assessment of CdTe and CdHgTe Toxicity and Clearance.

Dynamic near-infrared optical imaging of 2-deoxyglucose uptake by intracranial glioma of athymic mice.

S-Gal, a novel 1H MRI reporter for beta-galactosidase.

Imaging beta-galactosidase activity in human tumor xenografts and transgenic mice using a chemiluminescent substrate.

Upregulation of TRAG3 gene in urothelial carcinoma of the bladder.

On the potential for molecular imaging with Cerenkov luminescence.

A perspective on vascular disrupting agents that interact with tubulin: preclinical tumor imaging and biological assessment.

In vivo near-infrared spectroscopy and magnetic resonance imaging monitoring of tumor response to combretastatin A-4-phosphate correlated with therapeutic outcome.

Hexamethyldisiloxane-based nanoprobes for (1) H MRI oximetry.

Quantitative tissue oxygen measurement in multiple organs using 19F MRI in a rat model.