Hilary Ranson

Evolution of supergene families associated with insecticide resistance.

Heterologous expression of four glutathione transferase genes genetically linked to a major insecticide-resistance locus from the malaria vector Anopheles gambiae.

Malaria parasite and vector genomes: partners in crime.

The Anopheles gambiae glutathione transferase supergene family: annotation, phylogeny and expression profiles.

An adult-specific CYP6 P450 gene is overexpressed in a pyrethroid-resistant strain of the malaria vector, Anopheles gambiae.

The molecular basis of insecticide resistance in mosquitoes.

Characterization of the promoters of Epsilon glutathione transferases in the mosquito Anopheles gambiae and their response to oxidative stress.

The Anopheles gambiae detoxification chip: a highly specific microarray to study metabolic-based insecticide resistance in malaria vectors.

Elevated activity of an Epsilon class glutathione transferase confers DDT resistance in the dengue vector, Aedes aegypti.

An integrated genetic and physical map for the malaria vector Anopheles funestus.

Mosquito glutathione transferases.

Identification and analysis of single nucleotide polymorphisms (SNPs) in the mosquito Anopheles funestus, malaria vector.

Mapping a quantitative trait locus (QTL) conferring pyrethroid resistance in the African malaria vector Anopheles funestus.

Transcription profiling of a recently colonised pyrethroid resistant Anopheles gambiae strain from Ghana.

Detection of knockdown resistance (kdr) mutations in Anopheles gambiae: a comparison of two new high-throughput assays with existing methods.

The Aedes aegypti glutathione transferase family.

Genomic analysis of detoxification genes in the mosquito Aedes aegypti.

Pyrethroid tolerance is associated with elevated expression of antioxidants and agricultural practice in Anopheles arabiensis sampled from an area of cotton fields in Northern Cameroon.

Characterization of knockdown resistance in DDT- and pyrethroid-resistant Culex quinquefasciatus populations from Sri Lanka.

Lessons from the past: managing insecticide resistance in malaria control and eradication programmes.

Quantitative trait loci mapping of genome regions controlling permethrin resistance in the mosquito Aedes aegypti.

Development and application of a simple colorimetric assay reveals widespread distribution of sodium channel mutations in Thai populations of Aedes aegypti.

Expression of the cytochrome P450s, CYP6P3 and CYP6M2 are significantly elevated in multiple pyrethroid resistant populations of Anopheles gambiae s.s. from Southern Benin and Nigeria.

Field-caught permethrin-resistant Anopheles gambiae overexpress CYP6P3, a P450 that metabolises pyrethroids.

Two duplicated P450 genes are associated with pyrethroid resistance in Anopheles funestus, a major malaria vector.

Recent rapid rise of a permethrin knock down resistance allele in Aedes aegypti in México.

Exploring the molecular basis of insecticide resistance in the dengue vector Aedes aegypti: a case study in Martinique Island (French West Indies).

Insecticide resistance in Anopheles gambiae: data from the first year of a multi-country study highlight the extent of the problem.

Plasmodium infection alters Anopheles gambiae detoxification gene expression.

Transcriptomics and disease vector control.

Pyrethroid resistance in Aedes aegypti from Grand Cayman.

A simple colorimetric assay for specific detection of glutathione-S transferase activity associated with DDT resistance in mosquitoes.

Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control?

Mosquito age and susceptibility to insecticides.

Anopheles gambiae distribution and insecticide resistance in the cities of Douala and Yaoundé (Cameroon): influence of urban agriculture and pollution.

Extensive permethrin and DDT resistance in Anopheles arabiensis from eastern and central Sudan.

Dynamics of insecticide resistance in malaria vectors in Benin: first evidence of the presence of L1014S kdr mutation in Anopheles gambiae from West Africa.

Transcription of detoxification genes after permethrin selection in the mosquito Aedes aegypti.

Aging partially restores the efficacy of malaria vector control in insecticide-resistant populations of Anopheles gambiae s.l. from Burkina Faso.

Cytochrome b mutation Y268S conferring atovaquone resistance phenotype in malaria parasite results in reduced parasite bc1 catalytic turnover and protein expression.

Identification and validation of a gene causing cross-resistance between insecticide classes in Anopheles gambiae from Ghana.

Footprints of positive selection associated with a mutation (N1575Y) in the voltage-gated sodium channel of Anopheles gambiae.

Insecticide resistance in Culex quinquefasciatus from Zanzibar: implications for vector control programmes.

Detoxification enzymes associated with insecticide resistance in laboratory strains of Anopheles arabiensis of different geographic origin.

Gene amplification, ABC transporters and cytochrome P450s: unraveling the molecular basis of pyrethroid resistance in the dengue vector, Aedes aegypti.

Three years of insecticide resistance monitoring in Anopheles gambiae in Burkina Faso: resistance on the rise?

Multiple-insecticide resistance in Anopheles gambiae mosquitoes, Southern Côte d'Ivoire.

Pyrethroid resistance in Anopheles gambiae, in Bomi County, Liberia, compromises malaria vector control.

Additional selection for insecticide resistance in urban malaria vectors: DDT resistance in Anopheles arabiensis from Bobo-Dioulasso, Burkina Faso.

Dissecting the mechanisms responsible for the multiple insecticide resistance phenotype in Anopheles gambiae s.s., M form, from Vallée du Kou, Burkina Faso.

Identifying permethrin resistance loci in malaria vectors by genetic mapping.

Temephos resistance in Aedes aegypti in Colombia compromises dengue vector control.

Differential transcription profiles in Aedes aegypti detoxification genes after temephos selection.

The dynamics of pyrethroid resistance in Anopheles arabiensis from Zanzibar and an assessment of the underlying genetic basis.

Microarray and RNAi analysis of P450s in Anopheles gambiae male and female steroidogenic tissues: CYP307A1 is required for ecdysteroid synthesis.

Combining organophosphate treated wall linings and long-lasting insecticidal nets for improved control of pyrethroid resistant Anopheles gambiae.

A single mutation in the GSTe2 gene allows tracking of metabolically based insecticide resistance in a major malaria vector.

CYP6 P450 enzymes and ACE-1 duplication produce extreme and multiple insecticide resistance in the malaria mosquito Anopheles gambiae.

Identification of carboxylesterase genes implicated in temephos resistance in the dengue vector Aedes aegypti.

Metabolic and target-site mechanisms combine to confer strong DDT resistance in Anopheles gambiae.

The Sticky Resting Box, a new tool for studying resting behaviour of Afrotropical malaria vectors.

Insecticide resistance in Anopheles arabiensis in Sudan: temporal trends and underlying mechanisms.

Underpinning sustainable vector control through informed insecticide resistance management.

Molecular characterization of DDT resistance in Anopheles gambiae from Benin.

Increased pyrethroid resistance in malaria vectors and decreased bed net effectiveness, Burkina Faso.

Islands and stepping-stones: comparative population structure of Anopheles gambiae sensu stricto and Anopheles arabiensis in Tanzania and implications for the spread of insecticide resistance.

Dissecting the organ specificity of insecticide resistance candidate genes in Anopheles gambiae: known and novel candidate genes.

Long-term trends in Anopheles gambiae insecticide resistance in Côte d'Ivoire.

Long-lasting insecticide-treated house screens and targeted treatment of productive breeding-sites for dengue vector control in Acapulco, Mexico.

The recent escalation in strength of pyrethroid resistance in Anopheles coluzzi in West Africa is linked to increased expression of multiple gene families.

The AvecNet Trial to assess whether addition of pyriproxyfen, an insect juvenile hormone mimic, to long-lasting insecticidal mosquito nets provides additional protection against clinical malaria over current best practice in an area with pyrethroid-resistant vectors in rural Burkina Faso: study protocol for a randomised controlled trial.

Contrasting patterns of insecticide resistance and knockdown resistance (kdr) in the dengue vectors Aedes aegypti and Aedes albopictus from Malaysia.

To assess whether addition of pyriproxyfen to long-lasting insecticidal mosquito nets increases their durability compared to standard long-lasting insecticidal mosquito nets: study protocol for a randomised controlled trial.

When a discriminating dose assay is not enough: measuring the intensity of insecticide resistance in malaria vectors.

National malaria vector control policy: an analysis of the decision to scale-up larviciding in Nigeria.

Electrostatic coating enhances bioavailability of insecticides and breaks pyrethroid resistance in mosquitoes.

Detection of G119S ace-1 (R) mutation in field-collected Anopheles gambiae mosquitoes using allele-specific loop-mediated isothermal amplification (AS-LAMP) method.

Insecticide Resistance in African Anopheles Mosquitoes: A Worsening Situation that Needs Urgent Action to Maintain Malaria Control.

Averting a malaria disaster: will insecticide resistance derail malaria control?

Status of insecticide resistance in high-risk malaria provinces in Afghanistan.

An Operational Framework for Insecticide Resistance Management Planning.

Functional and immunohistochemical characterization of CCEae3a, a carboxylesterase associated with temephos resistance in the major arbovirus vectors Aedes aegypti and Ae. albopictus.

Spatial and Temporal Trends in Insecticide Resistance among Malaria Vectors in Chad Highlight the Importance of Continual Monitoring.

Delayed mortality effects cut the malaria transmission potential of insecticide-resistant mosquitoes.

Cytochrome P450 associated with insecticide resistance catalyzes cuticular hydrocarbon production in Anopheles gambiae.

Challenges and opportunities associated with the introduction of next-generation long-lasting insecticidal nets for malaria control: a case study from Burkina Faso.

The impact of pyrethroid resistance on the efficacy and effectiveness of bednets for malaria control in Africa.

Influence of the agrochemicals used for rice and vegetable cultivation on insecticide resistance in malaria vectors in southern Côte d'Ivoire.

Pyriproxyfen is metabolized by P450s associated with pyrethroid resistance in An. gambiae.

Fit for purpose: do we have the right tools to sustain NTD elimination?

Current and Future Prospects for Preventing Malaria Transmission via the Use of Insecticides.

Corrigendum to "Functional and immunohistochemical characterization of CCEae3a, a carboxylesterase associated with temephos resistance in the major arbovirus vectors Aedes aegypti and Ae. albopictus" [Insect Biochem. Mol. Biol. 74 (July 2016) 61-67].

The transcription factor Maf-S regulates metabolic resistance to insecticides in the malaria vector Anopheles gambiae.

House screening with insecticide-treated netting provides sustained reductions in domestic populations of Aedes aegypti in Merida, Mexico.

Insecticide-resistant malaria vectors must be tackled.

Efficacy of Olyset Duo, a bednet containing pyriproxyfen and permethrin, versus a permethrin-only net against clinical malaria in an area with highly pyrethroid-resistant vectors in rural Burkina Faso: a cluster-randomised controlled trial.

Unexpectedly high Plasmodium sporozoite rate associated with low human blood index in Anopheles coluzzii from a LLIN-protected village in Burkina Faso.

Piperonyl butoxide (PBO) combined with pyrethroids in insecticide-treated nets to prevent malaria in Africa.

Anopheline species composition and the 1014F-genotype in different ecological settings of Burkina Faso in relation to malaria transmission.

A testing cascade to identify repurposed insecticides for next-generation vector control tools: screening a panel of chemistries with novel modes of action against a malaria vector.

Mosquitoes cloak their legs to resist insecticides.

Characterisation of Anopheles strains used for laboratory screening of new vector control products.

Assessing the impact of the addition of pyriproxyfen on the durability of permethrin-treated bed nets in Burkina Faso: a compound-randomized controlled trial.

Barrier bednets target malaria vectors and expand the range of usable insecticides.

Functional genetic validation of key genes conferring insecticide resistance in the major African malaria vector, .

A sensory appendage protein protects malaria vectors from pyrethroids.

Anopheles gambiae populations from Burkina Faso show minimal delayed mortality after exposure to insecticide-treated nets.