Jochen Buck
Department of Pharmacology
Weill Cornell Medical College
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Bicarbonate-regulated soluble adenylyl cyclase.
JOP : Journal of the pancreas Jul, 2001 | Pubmed ID: 11875252
Bicarbonate-sensing soluble adenylyl cyclase is an essential sensor for acid/base homeostasis.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2010 | Pubmed ID: 20018667
Modulation of NaCl absorption by [HCO(3)(-)] in the marine teleost intestine is mediated by soluble adenylyl cyclase.
American journal of physiology. Regulatory, integrative and comparative physiology Jul, 2010 | Pubmed ID: 20410468
Physiological carbon dioxide, bicarbonate, and pH sensing.
Pflugers Archiv : European journal of physiology Nov, 2010 | Pubmed ID: 20683624
Intracellular cAMP signaling by soluble adenylyl cyclase.
Kidney international Jun, 2011 | Pubmed ID: 21490586
Physiological sensing of carbon dioxide/bicarbonate/pH via cyclic nucleotide signaling.
Sensors (Basel, Switzerland) , 2011 | Pubmed ID: 21544217
Metabolic communication between astrocytes and neurons via bicarbonate-responsive soluble adenylyl cyclase.
Neuron Sep, 2012 | Pubmed ID: 22998876
Neuronal expression of soluble adenylyl cyclase in the mammalian brain.
Brain research Jun, 2013 | Pubmed ID: 23611875
Pharmacological distinction between soluble and transmembrane adenylyl cyclases.
The Journal of pharmacology and experimental therapeutics Dec, 2013 | Pubmed ID: 24091307
Compartmentalization of distinct cAMP signaling pathways in mammalian sperm.
The Journal of biological chemistry Dec, 2013 | Pubmed ID: 24129574
Nonpigmented ciliary epithelial cells respond to acetazolamide by a soluble adenylyl cyclase mechanism.
Investigative ophthalmology & visual science Jan, 2014 | Pubmed ID: 24282227
pH sensing via bicarbonate-regulated "soluble" adenylyl cyclase (sAC).
Frontiers in physiology Nov, 2013 | Pubmed ID: 24324443
Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2014 | Pubmed ID: 24567411
A soluble adenylyl cyclase form targets to axonemes and rescues beat regulation in soluble adenylyl cyclase knockout mice.
American journal of respiratory cell and molecular biology Dec, 2014 | Pubmed ID: 24874272
A mitochondrial CO2-adenylyl cyclase-cAMP signalosome controls yeast normoxic cytochrome c oxidase activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Oct, 2014 | Pubmed ID: 25002117
Soluble adenylyl cyclase is necessary and sufficient to overcome the block of axonal growth by myelin-associated factors.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2014 | Pubmed ID: 25009261
The role of soluble adenylyl cyclase in health and disease.
Biochimica et biophysica acta Dec, 2014 | Pubmed ID: 25308880
Physiological roles of acid-base sensors.
Annual review of physiology , 2015 | Pubmed ID: 25340964
Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site.
The Journal of biological chemistry Apr, 2016 | Pubmed ID: 26961873
The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein.
Oncotarget Jul, 2016 | Pubmed ID: 27323809
Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.
Nature chemical biology 10, 2016 | Pubmed ID: 27547922
Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models.
Scientific reports 09, 2016 | Pubmed ID: 27627854
Soluble adenylyl cyclase is essential for proper lysosomal acidification.
The Journal of general physiology 10, 2016 | Pubmed ID: 27670898
Differential Intraocular Pressure Measurements by Tonometry and Direct Cannulation After Treatment with Soluble Adenylyl Cyclase Inhibitors.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 10, 2017 | Pubmed ID: 28686538
Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH.
Science signaling 11, 2018 | Pubmed ID: 30401788
Transient Sperm Starvation Improves the Outcome of Assisted Reproductive Technologies.
Frontiers in cell and developmental biology , 2019 | Pubmed ID: 31750304
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