Jochen Buck

Bicarbonate-regulated soluble adenylyl cyclase.

Bicarbonate-sensing soluble adenylyl cyclase is an essential sensor for acid/base homeostasis.

Modulation of NaCl absorption by [HCO(3)(-)] in the marine teleost intestine is mediated by soluble adenylyl cyclase.

Physiological carbon dioxide, bicarbonate, and pH sensing.

Intracellular cAMP signaling by soluble adenylyl cyclase.

Physiological sensing of carbon dioxide/bicarbonate/pH via cyclic nucleotide signaling.

Metabolic communication between astrocytes and neurons via bicarbonate-responsive soluble adenylyl cyclase.

Neuronal expression of soluble adenylyl cyclase in the mammalian brain.

Pharmacological distinction between soluble and transmembrane adenylyl cyclases.

Compartmentalization of distinct cAMP signaling pathways in mammalian sperm.

Nonpigmented ciliary epithelial cells respond to acetazolamide by a soluble adenylyl cyclase mechanism.

pH sensing via bicarbonate-regulated "soluble" adenylyl cyclase (sAC).

Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate.

A soluble adenylyl cyclase form targets to axonemes and rescues beat regulation in soluble adenylyl cyclase knockout mice.

A mitochondrial CO2-adenylyl cyclase-cAMP signalosome controls yeast normoxic cytochrome c oxidase activity.

Soluble adenylyl cyclase is necessary and sufficient to overcome the block of axonal growth by myelin-associated factors.

The role of soluble adenylyl cyclase in health and disease.

Physiological roles of acid-base sensors.

Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site.

The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein.

Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.

Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models.

Soluble adenylyl cyclase is essential for proper lysosomal acidification.

Differential Intraocular Pressure Measurements by Tonometry and Direct Cannulation After Treatment with Soluble Adenylyl Cyclase Inhibitors.

Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH.

Transient Sperm Starvation Improves the Outcome of Assisted Reproductive Technologies.