Andre F. Palmer

Self-assembled poly(butadiene)-b-poly(ethylene oxide) polymersomes as paclitaxel carriers.

Hemoglobin-based O2 carrier O2 affinity and capillary inlet pO2 are important factors that influence O2 transport in a capillary.

Purification of bovine hemoglobin via fast performance liquid chromatography.

Preparation of ultrapure bovine and human hemoglobin by anion exchange chromatography.

Biocompatible and biodegradable polymersome encapsulated hemoglobin: a potential oxygen carrier.

Site-selective glycosylation of hemoglobin on Cys beta93.

Hemoglobin-based oxygen carrier and convection enhanced oxygen transport in a hollow fiber bioreactor.

Tangential flow filtration of hemoglobin.

Perfluorocarbon facilitated O(2) transport in a hepatic hollow fiber bioreactor.

Purification of hemoglobin by tangential flow filtration with diafiltration.

The quaternary structure of tetrameric hemoglobin regulates the oxygen affinity of polymerized hemoglobin.

Effects of the molecular mass of tense-state polymerized bovine hemoglobin on blood pressure and vasoconstriction.

Mixtures of hemoglobin-based oxygen carriers and perfluorocarbons exhibit a synergistic effect in oxygenating hepatic hollow fiber bioreactors.

Large scale production of vesicles by hollow fiber extrusion: a novel method for generating polymersome encapsulated hemoglobin dispersions.

Tissue oxygenation after exchange transfusion with ultrahigh-molecular-weight tense- and relaxed-state polymerized bovine hemoglobins.

Functional comparison of hemoglobin purified by different methods and their biophysical implications.

Synthesis, biophysical properties and pharmacokinetics of ultrahigh molecular weight tense and relaxed state polymerized bovine hemoglobins.

High throughput assembly of spatially controlled 3D cell clusters on a micro/nanoplatform.

Hemoglobin regulates the metabolic, synthetic, detoxification, and biotransformation functions of hepatoma cells cultured in a hollow fiber bioreactor.

Hemoglobin regulates the metabolic and synthetic function of rat insulinoma cells cultured in a hollow fiber bioreactor.

Polymerization of human hemoglobin using the crosslinker 1,11-bis(maleimido)triethylene glycol for use as an oxygen carrier.

Biophysical properties and oxygenation potential of high-molecular-weight glutaraldehyde-polymerized human hemoglobins maintained in the tense and relaxed quaternary states.

Purification of hemoglobin from red blood cells using tangential flow filtration and immobilized metal ion affinity chromatography.

Effects of T- and R-state stabilization on deoxyhemoglobin-nitrite reactions and stimulation of nitric oxide signaling.

Synthesis and biophysical properties of polymerized human serum albumin.

Development of a dichloroacetic acid-hemoglobin conjugate as a potential targeted anti-cancer therapeutic.

Small-volume resuscitation from hemorrhagic shock using high-molecular-weight tense-state polymerized hemoglobins.

Structure of Greyhound hemoglobin: origin of high oxygen affinity.

Synthesis, biophysical properties, and oxygenation potential of variable molecular weight glutaraldehyde-polymerized bovine hemoglobins with low and high oxygen affinity.

Simple method for preparing poly(ethylene glycol)-surface-conjugated liposome-encapsulated hemoglobins: physicochemical properties, long-term storage stability, and their reactions with O2, CO, and NO.

Liposomes surface conjugated with human hemoglobin target delivery to macrophages.

Small-volume resuscitation from hemorrhagic shock with polymerized human serum albumin.

Simulation of NO and O(2) transport facilitated by polymerized hemoglobin solutions in an arteriole that takes into account wall shear stress-induced NO production.

Hypervolemic infusion of Lumbricus terrestris erythrocruorin purified by tangential-flow filtration.

Down selection of polymerized bovine hemoglobins for use as oxygen releasing therapeutics in a guinea pig model.

Encapsulation of hemoglobin inside liposomes surface conjugated with poly(ethylene glycol) attenuates their reactions with gaseous ligands and regulates nitric oxide dependent vasodilation.

Site-selective glycosylation of hemoglobin with variable molecular weight oligosaccharides: potential alternative to PEGylation.

Hemoglobin encapsulated poly(ethylene glycol) surface conjugated vesicles attenuate vasoactivity of cell-free hemoglobin.

High-efficiency matrix modulus-induced cardiac differentiation of human mesenchymal stem cells inside a thermosensitive hydrogel.

The Reactivity of Polymersome Encapsulated Hemoglobin with Physiologically Important Gaseous Ligands: Oxygen, Carbon Monoxide and Nitric Oxide.

Oxygen delivery during extreme anemia with ultra-pure earthworm hemoglobin.

Addition of ascorbic acid solution to stored murine red blood cells increases posttransfusion recovery and decreases microparticles and alloimmunization.

Scaffold architecture controls insulinoma clustering, viability, and insulin production.

Blood substitutes.

Biophysical Properties of Lumbricus terrestris Erythrocruorin and Its Potential Use as a Red Blood Cell Substitute.

Hemoglobin regulates the migration of glioma cells along poly(ε-caprolactone)-aligned nanofibers.

Modeling hemoglobin and hemoglobin:haptoglobin complex clearance in a non-rodent species-pharmacokinetic and therapeutic implications.

Evaluating the capacity to generate and preserve nitric oxide bioactivity in highly purified earthworm erythrocruorin: a giant polymeric hemoglobin with potential blood substitute properties.

Methemoglobin is an endogenous toll-like receptor 4 ligand-relevance to subarachnoid hemorrhage.

Cotransplantation of Polymerized Hemoglobin Reduces β-Cell Hypoxia and Improves β-Cell Function in Intramuscular Islet Grafts.

Haptoglobin Preserves Vascular Nitric Oxide Signaling during Hemolysis.

Transfusion with packed red blood cells while awaiting lung transplantation is associated with reduced survival after lung transplantation.

Quantification of Active Apohemoglobin Heme-Binding Sites via Dicyanohemin Incorporation.

The quaternary state of polymerized human hemoglobin regulates oxygenation of breast cancer solid tumors: A theoretical and experimental study.

Single cell analysis of aged RBCs: quantitative analysis of the aged cells and byproducts.

A Subpopulation of Monocytes in Normal Human Blood Has Significant Magnetic Susceptibility: Quantification and Potential Implications.

An Hb-mediated circulating macrophage contributing to pulmonary vascular remodeling in sickle cell disease.

Haptoglobin administration into the subarachnoid space prevents hemoglobin-induced cerebral vasospasm.

Novel manufacturing method for producing apohemoglobin and its biophysical properties.

Controlled Polymerization and Ultrafiltration Increase the Consistency of Polymerized Hemoglobin for Use as an Oxygen Carrier.

Quantification of the Mean and Distribution of Hemoglobin Content in Normal Human Blood Using Cell Tracking Velocimetry.

Injectable biodegradable bi-layered capsule for sustained delivery of bevacizumab in treating wet age-related macular degeneration.

Resuscitation From Hemorrhagic Shock With Fresh and Stored Blood and Polymerized Hemoglobin.

Poly(ethylene glycol) Surface-Conjugated Apohemoglobin as a Synthetic Heme Scavenger.

Apohemoglobin-haptoglobin complex attenuates the pathobiology of circulating acellular hemoglobin and heme.

Tangential flow filtration of haptoglobin.

Anti-inflammatory effects of haptoglobin on LPS-stimulated macrophages: Role of HMGB1 signaling and implications in chronic wound healing.

Targeted Myoglobin Delivery as a Strategy for Enhancing the Sensitivity of Hypoxic Cancer Cells to Radiation.

Comprehensive characterization of tense and relaxed quaternary state glutaraldehyde polymerized bovine hemoglobin as a function of cross-link density.

Balance between oxygen transport and blood rheology during resuscitation from hemorrhagic shock with polymerized bovine hemoglobin.

Apohemoglobin-haptoglobin complexes attenuate the hypertensive response to low-molecular-weight polymerized hemoglobin.

Hyperferritinemia in critically ill COVID-19 patients - Is ferritin the product of inflammation or a pathogenic mediator?

Polymerized human hemoglobin facilitated modulation of tumor oxygenation is dependent on tumor oxygenation status and oxygen affinity of the hemoglobin-based oxygen carrier.

Tumor vascular status controls oxygen delivery facilitated by infused polymerized hemoglobins with varying oxygen affinity.

Safety profile of high molecular weight polymerized hemoglobins.

Polymerized human hemoglobin increases the effectiveness of cisplatin-based chemotherapy in non-small cell lung cancer.

Vessel-on-a-chip models for studying microvascular physiology, transport, and function in vitro.

Early Intervention in Ischemic Tissue with Oxygen Nanocarriers Enables Successful Implementation of Restorative Cell Therapies.

Synthesis of Hemoglobin-Based Oxygen Carrier Nanoparticles By Desolvation Precipitation.

Purification of Mega-Hemoglobin for Diverse Oxygen Therapeutic Applications.

Resuscitation from hemorrhagic shock after traumatic brain injury with polymerized hemoglobin.

High fat high sucrose diet-induced dyslipidemia in guinea pigs.

Purification and analysis of a protein cocktail capable of scavenging cell-free hemoglobin, heme, and iron.

Structural Stability and Biophysical Properties of the Mega-Protein Erythrocruorin Are Regulated by Polyethylene Glycol Surface Coverage.

Immunomagnetic sequential ultrafiltration (iSUF) platform for enrichment and purification of extracellular vesicles from biofluids.

Polymerized albumin restores impaired hemodynamics in endotoxemia and polymicrobial sepsis.

Magnetophoretic and spectral characterization of oxyhemoglobin and deoxyhemoglobin: Chemical versus enzymatic processes.

Biophysical properties of tense quaternary state polymerized human hemoglobins bracketed between 500 kDa and 0.2 μm in size.

Tangential flow filtration facilitated fractionation and PEGylation of low and high-molecular weight polymerized hemoglobins and their biophysical properties.

Modern cross-linking strategies for synthesizing acellular hemoglobin-based oxygen carriers.

Mathematical model of NO and O2 transport in an arteriole facilitated by hemoglobin based O2 carriers.

Erythrocytes Are Oxygen-Sensing Regulators of the Cerebral Microcirculation.

Mixtures of tense and relaxed state polymerized human hemoglobin regulate oxygen affinity and tissue construct oxygenation.

Intrinsically magnetic susceptibility in human blood and its potential impact on cell separation: Non-classical and intermediate monocytes have the strongest magnetic behavior in fresh human blood.

Attenuating ischemia-reperfusion injury with polymerized albumin.

Polymerized Hemoglobin With Increased Molecular Size Reduces Toxicity in Healthy Guinea Pigs.

Enhanced Photodynamic Therapy Using the Apohemoglobin-Haptoglobin Complex as a Carrier of Aluminum Phthalocyanine.

Potential of cell tracking velocimetry as an economical and portable hematology analyzer.

Scalable manufacturing platform for the production of methemoglobin as a non-oxygen carrying control material in studies of cell-free hemoglobin solutions.

Lyophilized annelid mega-hemoglobin retains its' quaternary structure and oxygen equilibrium properties after room temperature storage for over 6 months.

Tangential flow filtration facilitated washing of human red blood cells: A proof-of-concept study.

Scalable production and complete biophysical characterization of poly(ethylene glycol) surface conjugated liposome encapsulated hemoglobin (PEG-LEH).

An immunogold single extracellular vesicular RNA and protein ( SERP) biochip to predict responses to immunotherapy in non-small cell lung cancer patients.

Scalable manufacturing platform for the production of PEGylated heme albumin.

Pilot scale production and characterization of next generation high molecular weight and tense quaternary state polymerized human hemoglobin.

Apohemoglobin-haptoglobin complex alleviates iron toxicity in mice with β-thalassemia via scavenging of cell-free hemoglobin and heme.

Sustained release of heme-albumin as a potential novel therapeutic approach for age-related macular degeneration.

Safety and efficacy of human polymerized hemoglobin on guinea pig resuscitation from hemorrhagic shock.

Biophysical Analysis and Preclinical Pharmacokinetics-Pharmacodynamics of Tangential Flow Filtration Fractionated Polymerized Human Hemoglobin as a Red Blood Cell Substitute.

Photocatalytic Synthesis of a Polydopamine-Coated Acellular Mega-Hemoglobin as a Potential Oxygen Therapeutic with Antioxidant Properties.

ZIF-8 metal organic framework nanoparticle loaded with tense quaternary state polymerized bovine hemoglobin: potential red blood cell substitute with antioxidant properties.

Biocompatibility of the oxygen carrier polymerized human hemoglobin towards HepG2/C3A cells.

Polymerized human hemoglobin with low and high oxygen affinity in trauma models.

Engineering Therapeutics to Detoxify Hemoglobin, Heme, and Iron.

ICAM-1-decorated extracellular vesicles loaded with miR-146a and drive immunomodulation and hinder tumor progression in a murine model of breast cancer.

The Molecular Size of Bioengineered Oxygen Carriers Determines Tissue Oxygenation in a Hypercholesterolemia Guinea Pig Model of Hemorrhagic Shock and Resuscitation.

Engineering a tunable micropattern-array assay to sort single extracellular vesicles and particles to detect RNA and protein in situ.

Polymerized Human Hemoglobin-Based Oxygen Carrier Preserves Lung Allograft Function During Normothermic Ex Vivo Lung Perfusion.

Macrophage modulation by polymerized hemoglobins: Potential as a wound-healing therapy.

Toxic side-effects of diaspirin cross-linked human hemoglobin are attenuated by the apohemoglobin-haptoglobin complex.

Novel high molecular weight polymerized hemoglobin in a non-obese model of cardiovascular and metabolic dysfunction.

Integrated Antigenic and Nucleic Acid Detection in Single Virions and Extracellular Vesicles with Viral Content.